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The Amniotic Fluid Proteome Differs Significantly between Donor and Recipient Fetuses in Pregnancies Complicated by Twin-to-Twin Transfusion Syndrome

Kim SM, Cho BK, Kim BJ, Lee HY, Norwitz ER, Kang MJ, Lee SM, Park CW, Jun JK, Yi EC, Park JS

BACKGROUND: Twin-to-twin transfusion syndrome (TTTS) is a serious complication of monochorionic twin pregnancies. It results from disproportionate blood supply to each fetus caused by abnormal vascular anastomosis within the placenta....
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Proteome Analysis of Alkylhydroxide Peroxidase-Deficient Isogenic Mutant of Helicobacter pylori 26695

Lee WK, Baik SC, Shin MK, Jung M, Park JS, Ha JH, Lee DH, Kim MJ, Shin JI, Kang HL

In order to investigate the antioxidant effect of alkylhydroxide peroxidase (ahpC) of Helicobacter pylori (H. pylori) 26695, an ahpC-deficient mutant (H. pylori 26695 ahpC::cat) was generated. ahpC-deficient mutant was grown...
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Memantine Improves Cognitive Function and Alters Hippocampal and Cortical Proteome in Triple Transgenic Mouse Model of Alzheimer's Disease

Zhou X, Wang L, Xiao W, Su Z, Zheng C, Zhang Z, Wang Y, Xu B, Yang X, Hoi MP

Memantine is a non-competitive N-methyl-D-aspartate receptor (NMDAR) antagonist clinically approved for moderate-to-severe Alzheimer's disease (AD) to improve cognitive functions. There is no report about the proteomic alterations induced by memantine...
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Mining the Proteome of Fusobacterium nucleatum subsp. nucleatum ATCC 25586 for Potential Therapeutics Discovery: An In Silico Approach

Habib AM, Islam MS, Sohel M, Mazumder M, Sikder MO, Shahik SM

The plethora of genome sequence information of bacteria in recent times has ushered in many novel strategies for antibacterial drug discovery and facilitated medical science to take up the challenge...
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Proteome Analysis of a Catalase-deficient Isogenic Mutant of Helicobacter pylori 26695

Kang HL, Lee SG, Park JS, Song JY, Cho MJ, Baik SC, Youn HS, Seo JH, Rhee KH, Lee WK

Helicobacter pylori, a gram-negative bacterium, is a causative agent of gastroduodenal diseases of human. Human immune system produces harmful reactive oxygen species to kill this bacterium that locates the microaerophilic...
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hpvPDB: An Online Proteome Reserve for Human Papillomavirus

Kumar S, Jena L, Daf S, Mohod K, Goyal P, Varma AK

Human papillomavirus (HPV) infection is the leading cause of cancer mortality among women worldwide. The molecular understanding of HPV proteins has significant connotation for understanding their intrusion in the host...
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Comparison of Proteome Component of Helicobacter pylori in Different Atmospheric CO2 Concentration

Lee SG, Kim KM, Park JW, Kwon YC, Song JY, Bae DW, Youn HS, Seo JH, Baik SC, Lee WK, Cho MJ, Rhee KH, Kang HL

Helicobacter pylori is a spiral, slow growing gram-negative microaerophilic bacterium. It has been shown to be the etiological agent of gastroduodenal diseases, such as chronic gastritis, gastric and duodenal ulcers,...
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Application of Hemin-Agarose Affinity Chromatography to Enrich Proteome Components of Helicobacter pylori Strain 26695

Kang HL, Baik SC

  • KMID: 1574111
  • J Bacteriol Virol.
  • 2005 Jun;35(2):77-85.
The whole cell extract of Helicobacter pylori strain 26695 was treated with the hemin-agarose resin and the bound fraction was analyzed by 2-Dimensional electrophoresis. The 2-D-PAGE-displayed spots were eluted and...
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The shear stress proteome of chondrocytes

Kim SY, Kim SG, Choi JY, Nahm DS

  • KMID: 2183841
  • J Korean Assoc Maxillofac Plast Reconstr Surg.
  • 2005 Jan;27(1):9-15.
The objective of this study is screening the shear stress related proteins in chondrocytes using twodimensional electrophresis and MALDI-TOF. C-28/I2 cell line were grown The fluid-induced shear stress (FISS) was...
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Proteome Analysis of Differential Protein Expression in Cervical Cancer Cells after Paclitaxel Treatment

Yim EK, Bae JS, Lee SB, Lee KH, Kim CJ, Namkoong S, Um SJ, Park JS

  • KMID: 2166132
  • Cancer Res Treat.
  • 2004 Dec;36(6):395-399.
PURPOSE: It is well known that infection with HPV (human papillomavirus) is the main cause of cervical cancer and certain types of HPV are recognized as carcinogens. At present, there...
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Analysis of the Cell Lysate Proteome of a Korean Mycobacterium tuberculosis Isolate K01 with H37Rv and H37Ra Strains

Ryu SW, Park SC, Bang MN, Han SS, Park YK, Park SN, Shim YS, Kang S, Bai GH

  • KMID: 2055002
  • J Bacteriol Virol.
  • 2004 Jun;34(2):107-112.
Despite recent economic prosperity, Korea still has high prevalence of tuberculosis. Molecular biologic characterization of Korean Mycobacterium tuberculosis strains might provide a deeper understanding of the forces contributing to the...
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Comparison of Serum Proteome Maps of Children with Kawasaki Disease

Baek SY, Lee YM, Lee KH, Kim DS

  • KMID: 2140982
  • Korean J Pediatr.
  • 2004 Jan;47(1):81-89.
PURPOSE: Kawasaki disease is a systemic vasculitis observed in children under five years of age and the leading cause of pediatric acquired heart disease, but its pathophysiology is still not...
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Identification of Proteome Molecules by Proteomics Using Two-Dimensional Gel Electrophoresis and MALDI-TOF MS

Song EJ, Lee KJ

  • KMID: 2038543
  • Korean J Infect Dis.
  • 2001 Dec;33(6):470-476.
Genomic technologies have enabled rapid accumulation of information from complex biological systems over the last two decades. The complete DNA sequence is now known for many organism and the informational...
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