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Predicting the Role of Osteal Macrophages and Osteocytes in Bone Tissue Network Using a Mathematical Modeling

Hwang SJ

The aim of this study was to investigate the role of osteal macrophages (osteomac) and osteocytes in bone remodeling using a mathematical model. We constructed the bone system with pre-osteoblasts,...
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Osteoblasts Are the Centerpiece of the Metastatic Bone Microenvironment

Jeong HM, Cho SW, Park SI

The tumor microenvironment is comprised of diverse stromal cell populations in addition to tumor cells. Increasing evidence now clearly supports the role of microenvironment stromal cells in tumor progression and...
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Factors and Mechanisms Involved in the Coupling from Bone Resorption to Formation: How Osteoclasts Talk to Osteoblasts

Ikeda K, Takeshita

Bone remodeling is the fundamental means by which the quality as well as quantity of the skeleton is maintained throughout adult life. When bone remodeling goes awry, a metabolic bone...
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The Effect of High Molecular Hyaluronic Acid on Bone Formation in Human Fetal Osteoblasts

Lee KS, Kim HA, Kim YS, You HK, Shin HS

No abstract available.
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Comparison of Bone Formation between Allogenic Periosteum-Derived Mesenchymal Stem Cells and Cultured Osteoblasts Transplanted into Long-Bone Defects of Rabbits

Kim HT, Lee CB, Youn MS, Lee JS, Jun ES, Chang HK

  • KMID: 2199065
  • J Korean Orthop Res Soc.
  • 2008 Oct;11(2):72-83.
PURPOSE: To analyze the bone formation between allogenic periosteum-derived mesenchymal stem cells and cultured osteoblasts transplanted into rabbit long-bone defects. MATERIALS AND METHODS: Forty white rabbits were grouped according to the...
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Effects of Mitomycin C on Cultured Rabbit Osteoblasts

Suh WJ, Chung WS

  • KMID: 2206043
  • J Korean Ophthalmol Soc.
  • 2001 Oct;42(10):1464-1469.
PURPOSE: To evaluate the effect of mitomycin C (MMC) on osteotomy site as an adjunctive therapeutic agent during dacryocystorhinostomy, the effect of MMC on cultured rabbit osteoblasts was tested. METHODS:...
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Study on the Biological Characteristics of Cultured Osteoblasts Derived from Alveolar Bone

Lee YB, Lee SJ, You SJ, Kim HA, You HK, Shin HS

Osteoblasts from alveolar bone may have an important role in the bone regeneration for periodontium, but their culture and characterization are not determined yet. The purpose of this study was...
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Interaction of Mesenchymal Stem Cells and Osteoblasts for in vitro Osteogenesis

Kim H, Lee JH, Suh H

It has recently been reported that bone marrow-derived mesenchymal stem cells (MSCs), which are systemically administrated to different species, undergo site-specific differentiation. This suggests that the tissue specific cells may...
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Induction of osteoclastogenesis-inducing cytokines and invasion by alive Aggregatibacter actinomycetemcomitans in osteoblasts

Choi HK, Lee YS, Kim MY, Kim KD, Cha JH, Yoo YJ

Osteoblasts regulate osteoclastogenesis by production of various cytokines. Aggregatibacter(A) actinomycetemcomitans is one of periodontopathogens which invades gingival tissue. Therefore, clarifying the effect of alive A. actinomycetemcomitans on osteoblasts is important...
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Effects of Reactive Oxygen Species on ATP-induced intracellular Ca2+ Activity in Osteoblasts

Kim JH, Kwon TD, Nam SH, Suh CK, Hong YW

BACKGORUND: The physiological activity of osteoblsts is known to be closely related to increased intracellular Ca2+ activity ([Ca2+ ]i) in osteoblasts. The cellular regulation of ([Ca2+ ]i) in osteoblasts...
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The Effect of Mitomycin C on Cultured Human Osteoblasts

Lee JH, Chung WS, Son JH

  • KMID: 2206690
  • J Korean Ophthalmol Soc.
  • 2003 Sep;44(9):2122-2127.
PURPOSE: To evaluate the effect of mitomycin-C (MMC) on osteotomy site as an adjunctive therapy for dacryocystorhinostomy, the effect of MMC on cultured human osteoblasts was tested. METHODS: Cultured osteoblasts...
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Clinical Applications of Autologous Cultured Osteoblasts: Case Report

Kim SJ, Ok IY, Chang CH, Kim YS, Jang JD, Bahk WJ, Lee JH

We treated 3 cases of fracture and 1 case of avascular necrosis of femoral head using autologous cultured osteoblasts injection. The stromal cells from the bone marrow were cultured to...
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The Biocompatibility of Human Osteoblasts to Porous Coated Nickel-Titanium Alloy (porous NiTi alloy) with Thermal Shape Memory

Chung DH, Kwon SY, Chung JW, Kim JC, Kang JW, Rhee SK

  • KMID: 2104903
  • J Korean Orthop Res Soc.
  • 2002 Oct;5(2):151-161.
PURPOSE: This research is to clarify utilization and efficiency of porous coated NiTi alloy by observing its affinity on human osteoblast. In this study, the biocompatibility of porous NiTi alloy...
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H2O2 Enhances Ca2+ Release from Osteoblast Internal Stores

Nam SH, Jung SY, Yoo CM, Ahn EH, Suh CK

The physiological activity of osteoblasts is known to be closely related to increased intracellular Ca2+ activity ([Ca2+]i) in osteoblasts. The cellular regulation of [Ca2+]i in osteoblasts is mediated by Ca2+...
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Immunocytochemical Study on Vimentin Expression in Osteoblasts and Osteocytes of Rat

Ryu SW, Song JY, Park JJ, Yoon JR

  • KMID: 1883449
  • Chonnam Med J.
  • 2004 Dec;40(4):180-185.
The osteoblast and osteocyte processes are filled with densely packed filaments, most of which have been previously shown to be actin microfilaments. However, the appearance of 10 nm diameter filaments...
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Luteolin Induces the Differentiation of Osteoblasts

Ko SY

  • KMID: 1457182
  • Int J Oral Biol.
  • 2010 Sep;35(3):99-106.
Luteolin is a flavonoid that exists in a glycosylated form in celery and green pepper. Flavonoids possess antioxidant and anti-inflammatory properties and can reduce the expression of key inflammatory molecules...
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The Affinitty of Human Osteoblast to A-W Glass Ceramics

Choi NY, Kim YS, Song HS

  • KMID: 2199185
  • J Korean Orthop Res Soc.
  • 1998 Oct;1(2):230-238.
The purpose of this study was to evaluate the biocompatibility of polystyrene, titanium, and A-W ceramic focusing on the affinity of osteoblasts to the metals. Human osteoblasts were cultivated with...
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Osteoimmunology: A Brief Introduction

Greenblatt MB, Shim JH

Recent investigations have demonstrated extensive reciprocal interactions between the immune and skeletal systems, resulting in the establishment of osteoimmunology as a cross-disciplinary field. Here we highlight core concepts and recent...
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Effects of Cervi Parvum Cornu on Cell Cycle Regulation in Human Fetal Osteoblasts

Yang DS, Kim HA, Hyun HN, You HK, Kim YC, Shin HS

Recently, many natural medicines, whose advantages are less side effects and possibility of long-term use, have been studied for their capacity, their anti-bacterial and anti-inflammatory effects and regenerative potential of...
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In Vitro Biological Activity of Osteoblasts on Nickel-Titanium Shape Memory Alloy

Kim YS, Rhee SK, Sohn JM, Chung JW, Choi DW, Kwon SY

  • KMID: 1828542
  • J Korean Orthop Res Soc.
  • 2001 Oct;4(2):177-182.
The unique properties of the nickel-titanium shape memory alloy (NiTi) have provided the enabling technology and potential for many applications in the orthopaedic and dental fields. In this study,...
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