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Radially patterned polycaprolactone nanofibers as an active wound dressing agent

Shin D, Kim MS, Yang CE, Lee WJ, Roh TS, Baek W

BACKGROUND: The objectives of this study were to design polycaprolactone nanofibers with a radial pattern using a modified electrospinning method and to evaluate the effect of radial nanofiber deposition on...
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Electrospun Collagen Nanofibers and Their Applications in Skin Tissue Engineering

Law JX, Liau LL, Saim A, Yang Y, Idrus R

Electrospinning is a simple and versatile technique to fabricate continuous fibers with diameter ranging from micrometers to a few nanometers. To date, the number of polymers that have been electrospun...
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Hybrid Additive Microfabrication Scaffold Incorporated with Highly Aligned Nanofibers for Musculoskeletal Tissues

Sooriyaarachchi D, Minière H, Maharubin , Tan GZ

BACKGROUND: Latest tissue engineering strategies for musculoskeletal tissues regeneration focus on creating a biomimetic microenvironment closely resembling the natural topology of extracellular matrix. This paper presents a novel musculoskeletal tissue...
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A Comparison of the Effects of Silica and Hydroxyapatite Nanoparticles on Poly(ε-caprolactone)-Poly(ethylene glycol)-Poly(ε-caprolactone)/Chitosan Nanofibrous Scaffolds for Bone Tissue Engineering

Raeisdasteh Hokmabad V, Davaran S, Aghazadeh , Alizadeh E, Salehi R, Ramazani A

BACKGROUND: The major challenge of tissue engineering is to develop constructions with suitable properties which would mimic the natural extracellular matrix to induce the proliferation and differentiation of cells. Poly(ε-caprolactone)-poly(ethylene...
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The influence of substrate topography and biomaterial substance on skin wound healing

Ghanavati , Neisi N, Bayati V, Makvandi M

Tissue engineering is a new field of which the main purpose is to regenerate and repair the damaged tissues. Scaffolds serve as three dimensional matrices for neo-organogenesis and their substance...
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Chitosan-Poly(Vinyl Alcohol) Nanofibers by Free Surface Electrospinning for Tissue Engineering Applications

Agrawal P, Pramanik K

Deformities in tissues and organs can be treated by using tissue engineering approach offering the development of biologically functionalized scaffolds from a variety of polymer blends which mimic the extracellular...
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Efficacy and Safety of the Electrospun Nanofibrous Adhesion Barrier for Laparoscopic Surgery in a Rabbit Model

Lee YW, Chu B, Lee YG, Kim NH, Kim JH, Kim KI, Kwon SW

PURPOSE: Most recently developed anti-adhesive membranes are not suitable for laparoscopic surgery due to weak mechanical properties or adhesive characteristics. To overcome these problems, we prepared electrospun bioabsorbable nanofibrous poly...
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Engineered M13 Nanofiber Accelerates Ischemic Neovascularization by Enhancing Endothelial Progenitor Cells

Lee JH, Kim SW, Ji ST, Kim YJ, Jang WB, Oh JW, Kim J, Yoo SY, Beak SH, Kwon SM

Dysfunction or loss of blood vessel causes several ischemic diseases. Although endothelial progenitor cells (EPCs) are a promising source for cell-based therapy, ischemia-induced pathophysiological condition limits the recovery rate by...
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Effects of Nanofiber Alignment and Strain Direction on Cellular Activities of Human ACL Fibroblasts

Lee CH, Shin HJ, Cho IH, Kang YM, Kim IA, Shin JW

  • KMID: 2042106
  • J Korean Orthop Res Soc.
  • 2004 Apr;7(1):1-12.
PURPOSE: The effects of fiber alignment and direction of mechanical strain on the ECM generation of human ACL fibroblast were assessed. MATERIALS AND METHODS: The aligned nanofiber was fabricated using electrospinning...
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Hybrid Nanofiber Scaffold-Based Direct Conversion of Neural Precursor Cells/Dopamine Neurons

Lim MS, Ko SH, Kim MS, Lee B, Jung HS, Kim K, Park CH

The concept of cellular reprogramming was developed to generate induced neural precursor cells (iNPCs)/dopaminergic (iDA) neurons using diverse approaches. Here, we investigated the effects of various nanoscale scaffolds (fiber, dot,...
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Effect of different sterilization methods on the surface morphology of PPDO-hybrid-PLGA nanofiber scaffold and attachments of PC12 cell

Lee J, Min H, Jung J, Kang N

  • KMID: 1485747
  • J Korean Assoc Oral Maxillofac Surg.
  • 2008 Dec;34(6):635-639.
OBJECTIVES: the effect of different sterilization methods on the surface morphology of PPDO-hybrid-PLGA nanofiber scaffold and attachments of PC12 cell were investigated. METHODS: Poly (p-dioxone)-hybrid-Poly (lactide-glycolide) (PPDO-hybrid-PLGA) nanofiber scaffold, fabricated in...
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The Study of the Regeneration of Nucleus Pulposususing Nanofiber-based Scaffold : In Vitro and Animal Study

Choi JS, An KC, Jang JH, Shin JW, Kim YJ

  • KMID: 2398744
  • J Korean Orthop Assoc.
  • 2006 Aug;41(4):721-729.
PURPOSE: To investigate the potential of nucleus pulposus (NP) regeneration with a nanofiber-based scaffold inserted in the degenerative disc. MATERIALS AND METHODS: A nanofiber scaffold was fabricated using an electrospinning technique....
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Development of the Three-Dimensional Perfusion Culture Technology for the Salivary Ductal Cells

Kim JW, Kim JM, Choi JS

BACKGROUND AND OBJECTIVES: Salivary hypofunction is one of the common side effects after radioiodine therapy, and its pathophysiology is salivary ductal stenosis resulting from ductal cell injury. This study aimed...
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A study on the biodegradable novel chitosan nanofiber membrane as a possible tool for guided bone regeneration

Shin SY, Park HN, Kim KH, Lee SJ, Park YJ, Ku Y, Rhyu IC, Han SB, Chung CP

  • KMID: 2321577
  • J Korean Acad Periodontol.
  • 2004 Sep;34(3):543-549.
Chitosan has been widely researched as bone substitution materials and membranes in orthopedic/periodontal applications. Chitosan nanofiber membrane was fabricated by chitosan nanofiber using electrospinning technique. The structure of the membrane...
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Effects of Poly-N-acetyl Glucosamine(pGlcNAc) Patch on Wound Healing in db/db Mouse

Yang HJ, Yoon CS

  • KMID: 2098569
  • J Korean Soc Plast Reconstr Surg.
  • 2008 Mar;35(2):121-126.
PURPOSE: Poly-N-acetyl glucosamine(PGlcNAc) nanofiber-based materials, produced by a marine microalga, have been characterized as effective hemostatic and angiogenic agents. The similarity between PGlcNAc patch and the natural extracellular matrix allows...
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Growth Behavior of Endothelial Cells According to Electrospun poly(D,L-Lactic-Co-Glycolic Acid) Fiber Diameter as a Tissue Engineering Scaffold

Ko YG, Park JH, Lee JB, Oh HH, Park WH, Cho D, Kwon OH

Investigating the effect of electrospun fiber diameter on endothelial cell proliferation provides an important guidance for the design of a fabric scaffold. In this study, we prepared biodegradable poly(D,L-lactic-co-glycolic acid)...
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