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Bone Morphogenetic Protein 2-Conjugated Silica Particles Enhanced Early Osteogenic Differentiation of Adipose Stem Cells on the Polycaprolactone Scaffold

Kim KJ, Choi MS, Shim JH, Rhie JW

BACKGROUND: Silica particles (SPs) induce cell proliferation and osteogenic differentiation. We reported that SPs in the scaffold induced early stage osteogenic differentiation. METHODS: A polycaprolactone (PCL) scaffold was fabricated with a...
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Silencing of LncRNA-ANCR Promotes the Osteogenesis of Osteoblast Cells in Postmenopausal Osteoporosis via Targeting EZH2 and RUNX2

Cai N, Li C, Wang F

PURPOSE: This study aimed to explore the effects and mechanisms of long non-coding RNA (lncRNA) anti-differentiation non-coding RNA (ANCR) on the osteogenesis of osteoblast cells in postmenopausal osteoporosis (PMOP). MATERIALS AND...
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Successful Treatment of Genital Warts with Ingenol Mebutate Monitored with Optical Coherence Tomography and Reflectance Confocal Microscopy

Reinholz M, Clanner-Engelshofen BM, Heppt MV, Hirai Y, Ruzicka T, Berking C, von Braunmühl T

Ingenol mebutate (IM) is approved for the treatment of actinic keratosis and induces cell death in precancerous lesions. The efficacy of IM in the treatment of genital warts was investigated...
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Monitoring Glutathione Dynamics and Heterogeneity in Living Stem Cells

Jeong EM, Shin JW, Lim J, Kim JH, Kang H, Yin Y, Kim HM, Kim Y, Kim SG, Kang HS, Shin DM, Choi K, Kim IG

Glutathione (GSH) is a major antioxidant in cells, and plays vital roles in the cellular defense against oxidants and in the regulation of redox signals. In a previous report, we...
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Comparative evaluation of marginal and internal fit of metal copings fabricated by various CAD/CAM methods

Jeong SJ, Cho HW, Jung JH, Kim JM, Kim YL

PURPOSE: The purpose of the present study was to compare the accuracy of four different metal copings fabricated by CAD/CAM technology and to evaluate clinical effectiveness. MATERIALS AND METHODS: Composite resin...
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Human spermatozoa anti-proprotein convertase subtilisin/kexin type 4 synthesis using New Zealand rabbit for novel immunocontraception in males

Dahril , Aulanni'am , Keumala V, Mustafa A

PURPOSE: Proprotein convertase subtilisin/kexin type 4 (PCSK4, a 54-kDa protease) is expressed in the plasma membrane of the acrosome in human spermatozoa. It plays a critical role in penetrating the...
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Effect of apoptosis on G361 cells by Cimicifuga rhizoma extract

Choi BB, Kim GC, Hong JW, Park SR

OBJECTIVES: To investigate whether the cytotoxic effect of Cimicifuga rhizoma extract is associated with cell death in the human keratinocyte (HaCaT) and human melanoma cell lines (G361). METHODS: Apoptosis induced by...
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Clinical Evaluation for Diabetic Neuropathy

Sohn EH

Diabetic polyneuropathy (DPN) causes neuropathic pain with reduced quality of life as well as diabetic foot ulceration which sometimes resulted in amputation. Early detection and improved knowledge of pathogenic pathways...
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Effect of dentin surface treatment and exclusive primer on bond strength of a self-adhesive resin cement

Lim GE, Son SA, Park JK

The purpose of this study was to evaluate the effect of different dentin surface treatments on the bond strength of self-adhesive resin cement (G-CEM one). Human permanent molars were sectioned...
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Application of Autofluorescence for Confocal Microscopy to Aid in Archaeoparasitological Analyses

Morrow JJ, Elowsky C

Confocal laser scanning microscopy (CLSM) was used to examine archaeoparasitological specimens from coprolites associated with La Cueva de los Muertos Chiquitos (CMC) located near present-day Durango, Mexico. The eggs for...
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Development of Macroporous Chitosan Scaffolds for Eyelid Tarsus Tissue Engineering

Sun MT, O'Connor A, Milne I, Biswas D, Casson R, Wood J, Selva D

BACKGROUND: Reconstruction of large eyelid defects remains challenging due to the lack of suitable eyelid tarsus tissue substitutes. We aimed to evaluate a novel bioengineered chitosan scaffold for use as...
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Utilization of Resin Infiltration for the Minimally Invasive Composite Restoration

Kim H, Park S, Jeong T, Kim S

This study was aimed to assess the new trial for minimal cavity preparation in composite restoration combined with resin infiltration, focusing at application sequence. 32 human primary molars with early carious...
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Respiratory syncytial virus increases eosinophil extracellular traps in a murine model of asthma

Silveira J, Antunes GL, Gassen RB, Breda RV, Stein RT, Pitrez PM, da Cunha A

BACKGROUND: Respiratory viral infections are the leading cause of asthma exacerbations. Eosinophil activation results in the formation of eosinophil extracellular traps (EETs), which release web-like structures of DNA and proteins...
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The bactericidal effect of an atmospheric-pressure plasma jet on Porphyromonas gingivalis biofilms on sandblasted and acid-etched titanium discs

Lee JY, Kim KH, Park SY, Yoon SY, Kim GH, Lee YM, Rhyu IC, Seol YJ

PURPOSE: Direct application of atmospheric-pressure plasma jets (APPJs) has been established as an effective method of microbial decontamination. This study aimed to investigate the bactericidal effect of direct application of...
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Surface alterations following instrumentation with a nylon or metal brush evaluated with confocal microscopy

Kim YS, Park JB, Ko Y

PURPOSE: Surface alterations of titanium discs following instrumentation with either a nylon brush or a metal brush were evaluated. METHODS: A total of 27 titanium discs with 3 surface types (9...
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A Modified Pretreatment with Deproteinization for Resin Infiltration in Early Childhood Caries

Nam S, Shin J, Jeong T, Kim S, Kim J

This study aimed to evaluate surface morphology and resin tag penetration of resin infiltration into primary anterior teeth after enamel deproteinization with sodium hypochlorite (NaOCl) prior to phosphoric acid (H₃PO₄)...
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Diagnosing Diabetic Neuropathy: Something Old, Something New

Petropoulos IN, Ponirakis , Khan A, Almuhannadi H, Gad H, Malik RA

There are potentially many ways of assessing diabetic peripheral neuropathy (DPN). However, they do not fulfill U.S. Food and Drug Administration (FDA) requirements in relation to their capacity to assess...
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The Different Expression Patterns of HSP22, a Late Embryogenesis Abundant-like Protein, in Hypertrophic H9C2 Cells Induced by NaCl and Angiotensin II

Sung JH, Song A, Park T, Kim E, Lee S

BACKGROUND: High-NaCl diet is a contributing factor for cardiac hypertrophy. The role of HSP22 as a protective protein during cardiac hypertrophy due to hypernatremia is unclear. Accordingly, this study aimed...
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Modulation of Electroosmotic Flow through Skin: Effect of Poly(Amidoamine) Dendrimers

Kim HJ, Oh SY

The objective of this work is to evaluate the effect of polyamidoamine (PAMAM) dendrimers on electroosmotic flow (EOF) through skin. The effect of size and concentration of dendrimer was studied,...
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Influence of size and insertion depth of irrigation needle on debris extrusion and sealer penetration

Uzunoglu-Özyürek E, Karaaslan , Türker SA, Özçelik

OBJECTIVES: To determine the effect of size and insertion depth of irrigation needle on the amount of apical extruded debris and the amount of penetration depth of sealer using a...
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