J Korean Ophthalmol Soc.  2013 Nov;54(11):1783-1787. 10.3341/jkos.2013.54.11.1783.

Confocal Microscopic Findings in Posterior Polymorphous Corneal Dystrophy

Affiliations
  • 1Department of Ophthalmology, Pusan National University Hospital, Pusan National University & Medical Research Institute School of Medicine, Busan, Korea. jongsool@pusan.ac.kr

Abstract

PURPOSE
To analyze the features of corneal tissue in patients with posterior polymorphous corneal dystrophy (PPMD) using in vivo confocal microscopy (IVCM).
CASE SUMMARY
Three patients with clinically diagnosed PPMD were examined using IVCM. Cross-sectioned corneal images of the corneal epithelium, Bowman's layer, stromal layer, Descemet's membrane, and endothelium were evaluated. IVCM demonstrated a depressed crater-like lesion, hyper-dense streak-like lesion, and surface irregularity of the corneal endothelium. Endothelial hypo-reflective vesicular and band-like lesions were also found. Pleomorphism and polymegathism were present with guttae and hyper-reflective endothelial nuclei.
CONCLUSIONS
IVCM is a non-invasive and effective tool to diagnose PPMD.

Keyword

Confocal microscopy; Posterior polymorphous corneal dystrophy

MeSH Terms

Corneal Dystrophies, Hereditary
Descemet Membrane
Endothelium
Endothelium, Corneal
Epithelium, Corneal
Humans
Microscopy, Confocal
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