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Transcriptome Analysis Identifies Altered Biological Processes and Novel Markers in Human Immunodeficiency Virus-1 Long-Term Non-Progressors

Lee D, Yoon CH, Choi SY, Kim JE, Cho YK, Choi BS, Park J

Background: The latent reservoir of Human Immunodificiency Virus-1 (HIV-1) has been a major barrier to the complete eradication of HIV-1 and the development of HIV therapy. Longterm non-progressors (LTNPs) are...
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Mini-Screws-Only Fixation Method for Small Fragments of Medial Malleolus Fractures

Choi BS, Lee SH, Kim MB, Lee YH

Background: Open reduction and internal fixation is the standard treatment for a displaced medial malleolus fracture (MMFx), achieving ankle stability and bony union to prevent post-traumatic arthritis. Previous fixation techniques...
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Successful treatment with vedolizumab in an adolescent with Crohn disease who had developed active pulmonary tuberculosis while receiving infliximab

Choi S, Choi BS, Choe BH, Kang B

Vedolizumab (VDZ) has been approved for the treatment of inflammatory bowel diseases (IBDs) in patients aged ≥18 years. We report a case of a pediatric patient with Crohn disease (CD)...
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Changes in the Occurrence of Gastrointestinal Infections after COVID-19 in Korea

Ahn SY, Park JY, Lim IS, Chae SA, Yun SW, Lee NM, Kim SY, Choi BS, Yi DY

Background: After the global epidemic of coronavirus disease 2019 (COVID-19), lifestyle changes to curb the spread of COVID-19 (e.g., wearing a mask, hand washing, and social distancing) have also affected...
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L-carnitine treatment attenuates renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction

Zhao HY, Li HY, Jin J, Jin JZ, Zhang LY, Xuan MY, Jin XM, Jiang YJ, Zheng HL, Jin YS, Jin YJ, Choi BS, Yang CW, Piao SG, Li C

Background/Aims: Accumulating evidence indicates that L-carnitine (LC) protects against multiorgan damage through its antioxidant properties and preservation of the mitochondria. Little information is available about the effects of LC on...
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Eosinophils and childhood asthma

Choi BS

Eosinophils are a type of granulocyte with eosinophilic granules in the cytoplasm that play an important role in allergic and parasitic diseases. Eosinophils are important in the pathogenesis of asthma,...
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Main epidemiological characteristics and natural history of pediatric allergic rhinitis

Kim M, Kim HH, Kim HB, Rha YH, Park Y, Sung M, Shin YH, Yum HY, Lee KS, Lee YJ, Chun YH, Jee HM, Choi BS, Choi SH, Park YM, on behalf of the Rhinitis Study Group in the Korean Academy of Pediatric Allergy and Respiratory Diseases

Allergic rhinitis (AR) is one of the most common allergic diseases characterized by stuffy nose, rhinorrhea, sneezing, and itching. Researchers have indicated an increase in the prevalence of AR and...
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Prevalence and risk factors of hyperkalemia early period after kidney transplantation

Lee S, Kim KM, Kim MH, Shin JH, Lim J, Hwang JK, Choi BS, Kim BS, Ban TH

Background: Electrolyte abnormality after kidney transplantation (KT) is common complications owing to immunosuppressive agents, prophylactic antibiotics, anti-hypertensive agents and uncontrolled diabetes. Hyperkalemia is a fatal electrolyte abnormality that often leads...
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Delayed Lesions on Diffusion-Weighted Imaging in Initially Lesion-Negative Stroke Patients

Kim K, Kim BJ, Huh J, Yang SK, Yang MH, Han MK, Jung C, Choi BS, Kim JH, Bae HJ

Background and Purpose Lesions on diffusion-weighted imaging (DWI) occasionally appear on follow-up magnetic resonance imaging (MRI) among initially DWI-negative but clinically suspicious stroke patients. We established the prevalence of positive...
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Development of donepezil-induced hypokalemia following treatment of cognitive impairment

Kim D, Yoon HE, Park HS, Shin SJ, Choi BS, Kim BS, Ban TH

Donepezil is a cholinesterase inhibitor used extensively to treat Alzheimer disease. The increased cholinergic activity is associated with adverse effects, therefore gastrointestinal symptoms, including nausea, vomiting, and diarrhea, are common....
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A Review of HPV Prevalence Research

Seong J, Ryou S, Choi BS

Human papillomavirus is known to be a major cause of cervical cancer. More than 190 HPV genotypes have been identified and classified into a high-risk group (18 genotypes) and a...
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Current Status of the Estimation on the Number of People Who Living with HIV and the Rate of Undiagnosed Cases

Yoo M, Yoon CH, Choi BS

Human immunodeficiency virus (HIV) is a major public health issue worldwide. As of 2018, 37.9 million people worldwide live with HIV, 1.7 million of which are new HIV infections, and...
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Clinical Evaluation of Atlas and Deep Learning-based Automatic Contouring of Multiple Organs at Risk and Clinical Target Volumes for Breast Cancer

Choi MS, Choi BS, Chung SY, Kim N, Chun J, Kim YB, Chang JS, Kim JS

  • KMID: 2510083
  • Prog Med Phys.
  • 2020 Sep;31(S1):S42.
Purpose: Advancements of radiotherapy developments for breast cancer may render more precise and conformal radiotherapy, designed to target the tumor and avoid normal organs on a much more individualized level....
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A Comparative Study on the Cognitive and Clinical Characteristics of Childhood/Adolescent- and Adult-Onset of Bipolar Disorder

Kim H, Huh SY, Kim SG, Kim JH, Jung WY, Yu Er, Choi BS, Kim DW, Yoon DU

  • KMID: 2503854
  • J Korean Soc Biol Ther Psychiatry.
  • 2020 Jun;26(2):154-161.
Objectives:Childhood/adolescent-onset of bipolar disorder presents functional impairments on emotional, academic, and social aspects. These impairments could continue into adulthood. However, there are few studies comparing cognitive function between childhood/adolescent- and...
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Concurrent and Adjuvant Temozolomide for Newly Diagnosed Grade IIIGliomas without 1p/19q Co-deletion: A Randomized, Open-Label,Phase 2 Study (KNOG-1101 Study)

Hwang K, Kim TM, Park CK, Chang JH, Jung TY, Kim JH, Nam DH, Kim SH, Yoo H, Hong YK, Kim EY, Lee DE, Joo J, Kim YJ, Choe G, Choi BS, Kang SG, Kim JH, Kim CY

Purpose We investigated the efficacy of temozolomide during and after radiotherapy in Korean adults with anaplastic gliomas without 1p/19q co-deletion. Materials and Methods This was a randomized, open-label, phase 2 study and notably the...
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Hyperkalemia developed from atorvastatin after kidney transplantation: a case report

Ban TH, Choi BS, Kim MH, Hwang JK, Lim J

Background: Hyperkalemia early after kidney transplantation (KT) is one of common complications owing to immunosuppressive agents, prophylactic antibiotics, and uncontrolled diabetes. However, it is difficult to predict that uncommon origins...
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Changes in Urine Osmolal Concentration with Lithium Treatment in Children and Youth with Bipolar Disorder

Jeong JW, Choi BS, Kim DW, Yu ER, Huh SY, Kim SG, Kim JH

Objectives Bipolar disorder has a high rate of recurrence, which can cause problems such as declines in cognitive and social functions. Lithium is the primary medication for preventing recurrence, but the...
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The Impact of Emotional Exhaustion on Psychological Factors in Workers with Secondary Traumatic Experiences: A Multi-Group Path Analysis

Jin MJ, Kim JS, Lee HS, Kwon YJ, Shim SH, Choi BS, Lee DW, Paik JW, Lee BC, Jung SW, Lee HY

Objective The objective of the present study was to explore causal pathways to understand how second traumatic experiences could affect the development of emotional exhaustion and psychiatric problems. Methods A total...
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Correlations of induced sputum eosinophils with blood allergic markers in pediatric asthma and eosinophilic bronchitis

Park BG, Kim H, Kwon JE, Kim DS, Choe JY, Ahn JY, Choi BS

Purpose: Induced sputum eosinophil count is useful for the evaluation and diagnosis of asthma and eosinophilic bronchitis (EB). The aim of this study was to evaluate the correlation of induced sputum...
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Clinical Characteristics of High-Grade Glioma with Primary Leptomeningeal Seeding at Initial Diagnosis in a Single Center Study

Kwon JE, Hwang K, Go KO, Wee CW, Kim IA, Kim YJ, Choe G, Choi BS, Han JH, Kim CY

Background High-grade glioma (HGG) with primary leptomeningeal seeding (PLS) at initial diagnosis is rare. The purpose of this study was to identify its clinical features and to describe the clinical...
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