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Effects of cisplatin on photosensitizer-mediated photodynamic therapy in breast tumor-bearing nude mice

Ahn TG, Jung JM, Lee EJ, Choi JH

OBJECTIVE: This study aimed to evaluate the potential effects of cisplatin on photodynamic therapy (PDT) in breast cancer using a breast tumor-bearing mouse model. METHODS: In this study, breast tumor (experimental...
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Local Subcutaneous Injection of Erythropoietin Might Improve Fat Graft Survival, Whereas Continuous Infusion Using an Osmotic Pump Device Was Harmful by Provoking an Overwhelming Foreign Body Reaction in a Nude Mouse Model

Kim EK, Lee Y, Lee HJ, Hong JP

BACKGROUND: Since the survival of grafted fat requires successful revascularization, we hypothesized that local delivery of erythropoietin (EPO), a hemangiogenic and antiapoptotic factor, might enhance the survival of fat grafts...
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The Feasibility of Platelet-Rich Fibrin Matrix Filler in a Nude Mouse Model

Jeon HJ, Kim DK, Lee JW, Choi KY, Chung HY, Cho BC, Shin JH, Lee SR, Yang JD

BACKGROUND: In contrast to fillers made from artificial substances, platelet-rich fibrin matrix (PRFM) filler does not cause hypersensitivity reactions or foreign body reactions. PRFM is also highly accessible in terms...
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Hydrogel and Platelet-Rich Plasma Combined Treatment to Accelerate Wound Healing in a Nude Mouse Model

Park YG, Lee IH, Park ES, Kim JY

BACKGROUND: Platelet-rich plasma (PRP) contains high concentrations of growth factors involved in wound healing. Hydrogel is a 3-dimensional, hydrophilic, high-molecular, reticular substance generally used as a dressing formulation to accelerate...
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Loquat (Eriobotrya japonica) leaf extract inhibits the growth of MDA-MB-231 tumors in nude mouse xenografts and invasion of MDA-MB-231 cells

You MK, Kim MS, Jeong KS, Kim E, Kim YJ, Kim HA

BACKGROUND/OBJECTIVES: The present study was conducted to examine the inhibitory effect of loquat leaves on MDA-MB-231 cell proliferation and invasion. MATERIALS/METHODS: Female athymic nude mice were given a subcutaneous (s.c.) inoculation...
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Bone Induction by Demineralized Dentin Matrix in Nude Mouse Muscles

Kim KW

  • KMID: 1704507
  • Maxillofac Plast Reconstr Surg.
  • 2014 Mar;36(2):50-56.
PURPOSE: This study examined the osteoinductive activity of demineralized human dentin matrix for nude mice. METHODS: Twenty healthy nude mice weighing about 15 to 20 g were used for study. Demineralized...
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The Schedule Dependency for Induction of Thymidine Phosphorylase Activity and the Enhancement of Capecitabine Efficacy by Docetaxel on the SNU-484 Gastric Cancer Cell Line That was Injected into Xenografted Nude Mice

Suh SB, Suh BJ, Kim JH, Yoo HJ

  • KMID: 2211126
  • J Korean Surg Soc.
  • 2007 Oct;73(4):294-301.
PURPOSE: Docetaxel (Taxotere(R)) and capecitabine are used in combination to treat advanced gastric cancer. Thymidine phosphorylase (TP) is an essential enzyme for the activation of capecitabine in tumors. This study...
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Osteogenic Differentiation of Human Adipose-derived Stem Cells within PLGA(Poly(D,L-lactic-co-glycolic acid)) Scaffold in the Nude Mouse

Yoo G, Cho SD, Byeon JH, Rhie JW

  • KMID: 2203231
  • J Korean Soc Plast Reconstr Surg.
  • 2007 Mar;34(2):141-148.
PURPOSE: The object of this study was to evaluate the development of continuous osteogenic differentiation and bone formation after the subcutaneous implantation of the tissue-engineered bone, in vitro. METHODS: Human adipose-derived...
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The Effect of Combination Therapy with Radiation and Selective Cyclooxygenase-2 Inhibitor on Xenografted Human Oral Cavity Squamous Cell Carcinoma in Nude Mice

Kim JH, Park SY, Kim HJ, Kim KB, Yang HS, Lee KS, Lee HJ, Ji YH

  • KMID: 2276625
  • Korean J Otolaryngol-Head Neck Surg.
  • 2006 Apr;49(4):420-425.
BACKGROUND AND OBJECTIVES: It is known that tumor cells over-expressing COX-2 have resistance to many anticancer treatments. Among those treatments, along with surgery and chemotherapy, radiation therapy plays a significant...
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Effect of the combined use of bone morphogenetic protein and platelet-derived growth factor on bone formation in nude mouse

Lee SH, Choi BH, Zhu SJ, Huh JY, Jung JH, Kim BY

Bone morphogenetic protein(BMP) and platelet-derived growth factor(PDGF) have been demonstrated tostimulate bone formation when applied locally in vivo. To explore whether or not the combined use of BMP and PDGF...
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The Effects of Dexamethasone on the Expansion and Transdifferentiation of Transplanted Porcine Neonatal Pancreas Cell Clusters into beta-cells in Normal Nude Mice

Yang JH, Suh SH, Jeon SY, Hong OK, Yoon KH

  • KMID: 2008164
  • J Korean Diabetes Assoc.
  • 2004 Oct;28(5):356-366.
BACKGROUND: Several studies have suggested that glucocorticoid has an influence on the development and function of the -cells. Thus, we undertook this study to determine whether exposure to dexamethasone...
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The inductive capacity of primary cultured oral mucosal keratinocytes in skin wound healing of athymic nude mice

Kim HS, Kim NH, Kim J, Cha IH

  • KMID: 1961096
  • J Korean Assoc Oral Maxillofac Surg.
  • 2004 Aug;30(4):308-315.
AIM: The aim of this study was to investigate the mechanism of promoted skin wound healing in skin defects with primary cultured oral mucosal keratinocytes. MATERIALS AND METHODS: Thirty adult female...
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Blood viscosity change in oral squamous cell carcinoma xenotransplanted nude mice

Myoung H, Lee JH, Choung PH, Kim MJ

  • KMID: 2190420
  • J Korean Assoc Oral Maxillofac Surg.
  • 2004 Apr;30(2):81-84.
It is well known that malignant tumor have hypoxic cell fraction, which is radio resistant and is one of the most important cause of local recurrence after radiotherapy. One of...
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Effect of Paclitaxel on PC-3 Cell Line Xenografted into Athymic Nude Mice

Kang SH, Cheon J, Yoon DK

  • KMID: 1764825
  • Korean J Urol.
  • 2004 Mar;45(3):263-267.
PURPOSE: Hormone-refractory prostate cancer(HRPC) is the terminal step in the natural history of prostate cancer, for which no chemotherapeutic agents have been shown to impact on the clinical outcomes. However,...
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Bone Formation by rhBMP-7 Transduced HEK 293 Cells in Nude Mouse

Jeong SY, Chang WT, Chang YS, Ahn MH, Kim JR, Song IH

To induce bone formation at ectopic site by tissue engineering and gene therapy, we transplanted collagen sponges containing rhBMP-7 transduced HEK 293 cells in the hypodermis of nude mice. Bone...
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Effect of Selective Cyclooxygenase-2 Inhibitor on Apoptosis of the Human Prostate Cancer Cell Xenografted in Nude Mice

Oh SY, Shin JH, Ahn JH, Noh BS, Ahn SH, Kim TH, Myoung SC, Kim YS, Bang HW, Lee TJ

  • KMID: 2293302
  • Korean J Urol.
  • 2003 Oct;44(10):1050-1057.
PURPOSE: Cyclooxygenase (COX)-2, an inducible enzyme that catalyzes the formation of prostaglandins from arachidonic acid, is overexpressed in various cancers, including prostate cancer, and cell lines. COX-2 has been reported...
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An experimental study on the therapeutic effect of ABNOBAviscum. on oral squamous cell carcinoma xenografted in nude mice

Jang MJ, Lee JH, Kim CH

  • KMID: 2183951
  • J Korean Assoc Maxillofac Plast Reconstr Surg.
  • 2003 Sep;25(5):383-397.
In recent studies, the treatment for oral cancer with chemotherapeutic agent is evaluated as an effective method to reduce cancer proliferation. However, minimization of serious side effects, such as bone...
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The Effect of Meloxicam on Tumor Growth and Angiogenesis of Human Gatric Cancer Cell Line Xenograft in Nude Mice

Lee YJ, Sim WJ, Cha SJ, Chi KC, Park SJ, Lim HM, Park SI, Lee TJ, Park ES

  • KMID: 2324957
  • J Korean Surg Soc.
  • 2001 Nov;61(5):465-473.
PURPOSE: In general, tumor growth is dependent on angiogenesis. COX, known as modulator of angiogenesis, consists of two at least isozymes constitutive COX-1 and stress- induced COX-2. The latter is...
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In Vivo Image and Biodistribution of 123I-15-(p-iodophenyl)-3-R , S - methylpentadecanoic acid ( BMIPP ) in Liposarcoma Bearing Nude Mice

Lee TS, Suh YS, Choi CW, Woo KS, Chung WS, Lim SJ, Lim SM, Awh OD

  • KMID: 1646917
  • Korean J Nucl Med.
  • 2001 Oct;35(5):324-333.
No abstract available.
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Anti-Tumor and Anti-Angiogenic Effect of Thalidomide on Oral Squamous Cell Carcinoma Xenografts in Nude Mice

Kim SG, Myoung H, Kim MJ

  • KMID: 2328356
  • J Korean Assoc Oral Maxillofac Surg.
  • 2001 Aug;27(4):330-336.
Angiogenesis is an essential process for the growth, invasion and metastasis of cancer. However, it is uncertain that antiangiogenic effects can be a major treatment strategy of oral cancer. The...
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