- A Case of Pathologic Splenic Rupture as the Initial Manifestation of Acute Myeloid Leukemia M2
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Han JS, Oh SY, Kim SH, Kwon HC, Hong SH, Han JY, Park KJ, Kim HJ
- KMID: 1779620
- Yonsei Med J.
- 2010 Jan;51(1):138-140.
- doi: 10.3349/ymj.2010.51.1.138
A pathologic splenic rupture refers to a rupture without trauma. A splenic rupture as the initial manifestation of acute myeloid leukemia is extremely rare. In this study, we described a... -
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- Myelodysplasia-Related Features of Acute Myeloid Leukemia Evolving From Philadelphia-Negative Myeloproliferative Neoplasms
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Kim JR, Cho YU, Bae MH, Kim B, Jang S, Seo EJ, Chi HS, Park CJ
- KMID: 2373561
- Ann Lab Med.
- 2016 Jul;36(4):377-379.
- doi: 10.3343/alm.2016.36.4.377
No abstract available. -
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- A Case of Lineage Switch from Acute Lymphoblastic Leukemia to Acute Myeloid Leukemia
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Chung HJ, Park CJ, Jang S, Chi HS, Seo EJ, Seo JJ
- KMID: 1781467
- Korean J Lab Med.
- 2007 Apr;27(2):102-105.
- doi: 10.3343/kjlm.2007.27.2.102
Lineage switch from acute lymphoblastic leukemia (ALL) to acute myeloid leukemia (AML) is very rare. We report a case of a 9 yr-old ALL patient relapsed as acute myelomonocytic leukemia.... -
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- MLL-SEPT5 Fusion Transcript in Two de novo Acute Myeloid Leukemia Patients With t(11;22)(q23;q11)
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Wang N, Wu X, Sheng G, Ma L, Wen L, Yao H, Chen S
- KMID: 2373585
- Ann Lab Med.
- 2016 Sep;36(5):501-503.
- doi: 10.3343/alm.2016.36.5.501
No abstract available. -
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- Lineage Switch at Relapse of Childhood Acute Leukemia: A Report of Four Cases
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Park M, Koh KN, Kim BE, Im HJ, Jang S, Park CJ, Chi HS, Seo JJ
- KMID: 1785972
- J Korean Med Sci.
- 2011 Jun;26(6):829-831.
- doi: 10.3346/jkms.2011.26.6.829
Lineage switch in acute leukemia is an uncommon event at relapse, and therefore rarely reported in the literature. Here, we have described the clinical laboratory features of four cases in... -
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- Cell Population Data NE-SFL and MO-WX From Sysmex XN-3000 Can Provide Additional Information for Exclusion of Acute Promyelocytic Leukemia From Other Acute Myeloid Leukemias: A Preliminary Study
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Park SH, Kim HH, Kim IS, Yi J, Chang CL, Lee EY
- KMID: 2373602
- Ann Lab Med.
- 2016 Nov;36(6):607-610.
- doi: 10.3343/alm.2016.36.6.607
No abstract available. -
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- Clinical Utility of Fluorescence in-situ Hybridization Profile Test in Detecting Genetic Aberrations in Acute Leukemia
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Kim SR, Kim HJ, Kim SH
- KMID: 1077410
- Korean J Lab Med.
- 2009 Oct;29(5):371-378.
- doi: 10.3343/kjlm.2009.29.5.371
BACKGROUND: Cytogenetic abnormalities are one of the most reliable prognostic factors in acute leukemia. Combination of conventional chromosome analysis (CCA) and FISH provides higher sensitivity in detecting these genetic abnormalities,... -
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- Acute Myeloid Leukemia With MLL Rearrangement and CD4+/CD56+ Expression can be Misdiagnosed as Blastic Plasmacytoid Dendritic Cell Neoplasm: Two Case Reports
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Lee JM, Kim IS, Lee JN, Park SH, Kim HH, Chang CL, Lee EY, Kim HR, Oh SH, Song SA
- KMID: 2373582
- Ann Lab Med.
- 2016 Sep;36(5):494-497.
- doi: 10.3343/alm.2016.36.5.494
No abstract available. -
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- Clinical Characteristics of 75 Patients with Leukemia Cutis
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Kang YS, Kim HS, Park HJ, Lee JY, Kim HO, Cho BK, Park YM
- KMID: 1786972
- J Korean Med Sci.
- 2013 Apr;28(4):614-619.
- doi: 10.3346/jkms.2013.28.4.614
Leukemia cutis (LC) is defined as a neoplastic leukocytic infiltration of the skin. Few clinical studies are available on recent trends of LC in Korea. The purpose of this study... -
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- Three-way Translocation of MLL/MLLT3, t(1;9;11)(p34.2;p22;q23), in a Pediatric Case of Acute Myeloid Leukemia
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Jun KR, Lee JN, Park JA, Kim HR, Shin JH, Oh SH, Lee JY, Song SA
- KMID: 1094354
- Korean J Lab Med.
- 2011 Apr;31(2):127-129.
- doi: 10.3343/kjlm.2011.31.2.127
The chromosome band 11q23 is a common target region of chromosomal translocation in different types of leukemia, including infantile leukemia and therapy-related leukemia. The target gene at 11q23, MLL, is... -
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- The First Korean Case of Childhood Acute Myeloid Leukemia with Inv(11)(p15q22)/NUP98-DDX10 Rearrangement: A Rare but Recurrent Genetic Abnormality
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Choi R, Jang MA, Yoo KH, Lee ST, Kim HJ, Kim SH
- KMID: 2129577
- Ann Lab Med.
- 2014 Nov;34(6):478-480.
- doi: 10.3343/alm.2014.34.6.478
No abstract available. -
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- Characteristics of Acute Myeloid Leukemia without HLA-DR Expression
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Moon H, Lee S, Huh J, Chung WS
- KMID: 1781528
- Korean J Lab Med.
- 2007 Oct;27(5):313-317.
- doi: 10.3343/kjlm.2007.27.5.313
BACKGROUND: HLA-DR negativity is known to be useful for distinguishing acute promyelocytic leukemia (APL) from other subtypes of AML, but non-APL cases without HLA-DR antigen expression have been reported.... -
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- Overexpression of X-linked Inhibitor of Apoptosis Protein (XIAP) is an Independent Unfavorable Prognostic Factor in Childhood de Novo Acute Myeloid Leukemia
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Sung KW, Choi J, Hwang YK, Lee SJ, Kim HJ, Kim JY, Cho EJ, Yoo KH, Koo HH
- KMID: 1779191
- J Korean Med Sci.
- 2009 Aug;24(4):605-613.
- doi: 10.3346/jkms.2009.24.4.605
The overexpression of X-linked inhibitor of apoptosis protein (XIAP), a member of IAP family protein, is intuitively expected to be associated with unfavorable clinical features in malignancies; however, there have... -
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- Therapy-Related Myeloid Neoplasms in 39 Korean Patients: A Single Institution Experience
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Huh HJ, Lee SH, Yoo KH, Sung KW, Koo HH, Kim K, Jang JH, Jung C, Kim SH, Kim HJ
- KMID: 1781307
- Ann Lab Med.
- 2013 Mar;33(2):97-104.
- doi: 10.3343/alm.2013.33.2.97
BACKGROUND: Therapy-related myeloid neoplasms (t-MN) occur as late complications of cytotoxic therapy. This study reviewed clinical and cytogenetic characteristics of patients with t-MN at a single institution in Korea. METHODS: The... -
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- Clinical Significance of Previously Cryptic Copy Number Alterations and Loss of Heterozygosity in Pediatric Acute Myeloid Leukemia and Myelodysplastic Syndrome Determined Using Combined Array Comparative Genomic Hybridization plus Single-Nucleotide Polymorphism Microarray Analyses
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Koh KN, Lee JO, Seo EJ, Lee SW, Suh JK, Im HJ, Seo JJ
- KMID: 1789951
- J Korean Med Sci.
- 2014 Jul;29(7):926-933.
- doi: 10.3346/jkms.2014.29.7.926
The combined array comparative genomic hybridization plus single-nucleotide polymorphism microarray (CGH+SNP microarray) platform can simultaneously detect copy number alterations (CNA) and copy-neutral loss of heterozygosity (LOH). Eighteen children with acute... -
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- Ring Chromosome 5 in Acute Myeloid Leukemia Defined by Whole-genome Single Nucleotide Polymorphism Array
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Huh J, Mun YC, Chung WS, Seong CM
- KMID: 1380093
- Ann Lab Med.
- 2012 Jul;32(4):307-311.
- doi: 10.3343/alm.2012.32.4.307
Chromosomes forming a corresponding ring cannot be clearly defined by conventional cytogenetics or FISH. Karyotypic analyses using whole-genome single nucleotide polymorphism arrays (SNP-A) may result in the identification of previously... -
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- Minimal Residual Disease Detection in Acute Leukemia Patients by Flow Cytometric Assay of Cross-lineage Antigen Expression
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Cho YU, Park CJ, Cha CH, Chi HS, Jang S, Kim MJ, Lee KH, Lee JH, Lee JH, Seo JJ, Im HJ
- KMID: 1781655
- Korean J Lab Med.
- 2010 Dec;30(6):533-539.
- doi: 10.3343/kjlm.2010.30.6.533
BACKGROUND: It has been demonstrated that flow cytometric detection of minimal residual disease (MRD) has a prognostic significance in the treatment of patients with acute leukemia. We investigated the significance... -
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- Additional Genomic Aberrations Identified by Single Nucleotide Polymorphism Array-Based Karyotyping in an Acute Myeloid Leukemia Case with Isolated del(20q) Abnormality
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Hahm C, Mun YC, Seong CM, Chung WS, Huh J
- KMID: 2434489
- Ann Lab Med.
- 2012 Nov;32(6):445-449.
Prognosis is known to be better in cases with isolated chromosomal abnormalities than in those with complex karyotypes. Accordingly, del(20q) as an isolated abnormality must be distinguished from cases in... -
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- Incidences and Prognostic Impact of c-KIT, WT1, CEBPA, and CBL Mutations, and Mutations Associated With Epigenetic Modification in Core Binding Factor Acute Myeloid Leukemia: A Multicenter Study in a Korean Population
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Park SH, Lee HJ, Kim IS, Kang JE, Lee EY, Kim HJ, Kim YK, Won JH, Bang SM, Kim H, Song MK, Chung JS, Shin HJ
- KMID: 2363200
- Ann Lab Med.
- 2015 May;35(3):288-297.
- doi: 10.3343/alm.2015.35.3.288
BACKGROUND: To identify potential molecular prognostic markers in core binding factor (CBF) AML, we analyzed incidences and prognostic impacts of mutations in c-KIT, WT1, CEBPA, CBL, and a number of... -
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