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A Novel PA-X Protein Translated from Influenza A Virus Segment 3

Lee I, Kim JI, Park MS

The pathogenicity of influenza A viruses is a multigenic trait, which is orchestrated by the global networks between eight viral genomic constituents and their cellular interacting partners. A recent report...
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An Universal Approach to Getting Ahead for Influenza B Vaccines

Kim JI, Park MS

Cross-reactive neutralizing antibodies against influenza A viruses have received attention for their potentials for prophylactic and therapeutic. These antibodies usually bind to relatively conserved stem domains of influenza hemagglutinin, one...
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Regulation of Obesity and Non-alcoholic Fatty Liver Diseases by Modulation of the Gut Microbiota Through Inflammasome; its Mechanism and Potential for Clinical Use

Nam JH

The revelation that gut microbes are associated with the pathogenesis of human diseases such as obesity, colon cancer, inflammatory bowel disease and liver-related diseases has resulted in the role of...
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Bacterial 23S Ribosomal RNA, a Ligand for Toll-like Receptor 13

Manzoor Z, Koh YS

Toll-like receptors are required for detection of pathogen-associated molecular patterns and play critical roles in protection of host from infection. Murine TLR13 was recently reported to be involved in recognition...
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Detection of Neutralizing Antibody Against Japanese Encephalitis Virus in Wild Boars of Korea

Yang DK, Kim HH, Hyun BH, Lim SI, Nam YK, Nah JJ, Song JY

Several species of animals, including horses and pigs, can be infected with Japanese encephalitis virus (JEV). Wild boars (Sus scrofa) are also considered to be an effective amplifying host for...
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Inhibition of Transfer Infection of Epstein-Barr Virus to Epithelial Cells by Integrin beta6 siRNA

Kim SY, Lee SK

Epstein-Barr virus (EBV) establishes a latent infection in greater than 90% of the world's adult population and associates with various tumors. EBV primarily infects epithelial cells and B cell in...
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Detection of Adeno-associated Virus from Semen Suffering with Male Factor Infertility and Having Their Conception Partners with Recurrent Miscarriages

Kim CH, Kim JH, Kim HJ, Kim KW, Lee JY, Yang SH, Choe J, Hwang D, Kim KC, Hwang ES

Adeno-associated virus (AAV) and human papillomavirus (HPV) DNAs were found in abnormal quality semen, early abortus and female genital tissues. It was suggested that they might cause male infertility and...
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Generation and Biological Characterization of a Neutralization-Resistant Mutant of Newcastle Disease Virus

Park MJ, Kye SJ, Kim JY, Kim S, Seul HJ, Park CK, Choi KS

A neutralization-resistant mutant of Newcastle disease virus (NDV) Kr005 strain belonging to class II genotype VII was generated using a neutralizing monoclonal antibody and its biological effects were assessed. The...
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Isolation and Cloning of an ABC Transporter-Like Gene of Haemophilus parasuis and Its Use in a New Diagnostic PCR

Kim H, Cho Y, Shin S, Kang S, Kwon OB, Hahn TW

The aim of this study was to identify a new gene of Haemophilus parasuis that could be used to develop a polymerase chain reaction (PCR) test for this porcine pathogen....
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Characterization of Bacterial Community Contaminating Floor of A Hot and Dry Sauna

Lee JY, Park DH

The purpose of this study was to examine profile of bacteria contaminated in a dry sauna. Bacteria sampled from the floor of the dry sauna (75~80degrees C) were separated and...
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Comparison of the Antibiotic Resistance of Helicobacter pylori Isolated in Jinju Over a 15-year Period

Seo JH, Koo SI, Youn HS, Jun JS, Lim JY, Park CH, Woo HO, Kang HL, Baik SC, Lee WK, Cho MJ, Rhee KH

The aims of this study were to investigate the changing pattern of Helicobacter pylori antibiotic resistance in Jinju over a 15-year period. H. pylori strains were isolated from 170 adults...
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Coordinate Regulation of Vibrio vulnificus Heme Receptor HupA Expression by Cyclic AMP-receptor Protein and Ferric Uptake Regulator

Kim SP, Lee GW, Kim CM, Shin SH

Vibrio vulnificus causes rapid progressing fulminant infections in susceptible individuals, especially those with elevated serum iron levels. This ferrophilic bacterium can directly acquire iron from heme-containing proteins, such as, hemoglobin,...
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Antiviral Agents Against Influenza Viruses

Park S, Kim JI, Park MS

In annual epidemics and occasional pandemics, influenza viruses cause acute respiratory illnesses in infected humans. Vaccines and antiviral drugs are two main arsenals available for a fight against influenza viruses....
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Cellular and Systemic Interactions of Orientia tsutsugamushi with Mammalian Host

Kim SY, Choi MS, Cho NH

Scrub typhus is an acute febrile illness caused by Orientia tsutsugamushi infection and one of main causes of febrile illness in the Asia-Pacific region. It has been estimated that one...
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Application of Metagenomic Techniques: Understanding the Unrevealed Human Microbiota and Explaining the in Clinical Infectious Diseases

Kim W

Uncultured microorganisms comprise the majority of the planet's biological diversity. In many environments, as many as 99% of the microorganisms cannot be cultured by standard techniques, and the uncultured fraction...
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