J Bacteriol Virol.  2012 Dec;42(4):357-358. 10.4167/jbv.2012.42.4.357.

Bacterial 23S Ribosomal RNA, a Ligand for Toll-like Receptor 13

• Manzoor Z
• Koh YS

• KMID: 2168672
• DOI: http://doi.org/10.4167/jbv.2012.42.4.357

Abstract

Toll-like receptors are required for detection of pathogen-associated molecular patterns and play critical roles in protection of host from infection. Murine TLR13 was recently reported to be involved in recognition of bacterial 23S ribosomal RNA sequence that is the binding site of different antibiotics.

Keyword

Toll-like receptor; Toll-like receptor 13; Bacterial ribosomal RNA; Staphylococcus aureus

MeSH Terms

Anti-Bacterial Agents
Binding Sites
RNA, Ribosomal, 23S
Staphylococcus aureus
Toll-Like Receptors
Anti-Bacterial Agents
RNA, Ribosomal, 23S
Toll-Like Receptors

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