- In Vivo Generation of Organs by Blastocyst Complementation: Advances and Challenges
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Founta KM, Papanayotou C
- KMID: 2529783
- Int J Stem Cells.
- 2022 May;15(2):113-121.
- doi: 10.15283/ijsc21122
The ultimate goal of regenerative medicine is to replace damaged cells, tissues or whole organs, in order to restore their proper function. Stem cell related technologies promise to generate transplants... -
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- The Differentiation of Pluripotent Stem Cells towards Endothelial Progenitor Cells – Potential Application in Pulmonary Arterial Hypertension
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Qin K, Lei J, Yang J
- KMID: 2529784
- Int J Stem Cells.
- 2022 May;15(2):122-135.
- doi: 10.15283/ijsc21044
Background and Objectives: Endothelial progenitor cells (EPCs) and endothelial cells (ECs) have been applied in the clinic to treat pulmonary arterial hypertension (PAH), a disease characterized by disordered pulmonary vasculature.... -
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- Psoriatic Serum Induce an Abnormal Inflammatory Phenotype and a Decreased Immunosuppressive Function of Mesenchymal Stem Cells
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Wang F, Hou R, Li J, Zhao X, Wang Q, Zhang K, Li X
- KMID: 2529787
- Int J Stem Cells.
- 2022 May;15(2):155-163.
- doi: 10.15283/ijsc20210
Background and Objectives: Mesenchymal stem cells (MSCs) have immunomodulatory function and participate in the pathogenesis of many immunoregulation-related diseases, including psoriasis. Previously, we found that MSCs from psoriatic lesions overexpress... -
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- Reduced Osteogenic Differentiation Potential In Vivo in Acute Myeloid Leukaemia Patients Correlates with Decreased BMP4 Expression in Mesenchymal Stromal Cells
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Azevedo PL, Dias RB, Nogueira LP, Maradei S, Bigni R, Aragao JSR, Abdelhay E, Binato R
- KMID: 2529837
- Int J Stem Cells.
- 2022 May;15(2):227-232.
- doi: 10.15283/ijsc21138
The osteogenic differentiation potential of mesenchymal stromal cells (hMSCs) is an essential process for the haematopoiesis and the maintenance of haematopoietic stem cells (HSCs). Therefore, the aim of this work... -
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- BMP‑6 Attenuates Oxygen and Glucose Deprivation-Induced Apoptosis in Human Neural Stem Cells through Inhibiting p38 MAPK Signaling Pathway
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Wang L, Chen Y, Wei L, He J
- KMID: 2529786
- Int J Stem Cells.
- 2022 May;15(2):144-154.
- doi: 10.15283/ijsc21093
Background and Objectives: Neural stem cells (NSCs) remain in the mammalian brain throughout life and provide a novel therapeutic strategy for central nervous system (CNS) injury. Bone morphogenetic protein-6 (BMP-6)... -
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- Single-Cell RNA Sequencing of Bone Marrow Mesenchymal Stem Cells from the Elderly People
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Zhu D, Gao J, Tang C, Xu Z, Sun T
- KMID: 2529789
- Int J Stem Cells.
- 2022 May;15(2):173-182.
- doi: 10.15283/ijsc21042
Background and Objectives: Bone marrow mesenchymal stem cells (BMSCs) show considerable promise in regenerative medicine. Many studies demonstrated that BMSCs cultured in vitro were highly heterogeneous and composed of diverse... -
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- Evaluation of the Potential Effects of Retinol and Alginate/Gelatin-Based Scaffolds on Differentiation Capacity of Mouse Mesenchymal Stem Cells (MSCs) into Retinal Cells
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Haghighat M, Iranbakhsh A, Baharara J, Ebadi M, Sotoodehnejadnematalahia F
- KMID: 2529790
- Int J Stem Cells.
- 2022 May;15(2):183-194.
- doi: 10.15283/ijsc21062
Background and Objectives: Retinal stem cells (RSCs) resided in ciliary epithelium have shown to possess a high ca-pacity to self-renew and differentiate into retinal cells. RSCs could be induced to... -
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- Pharmaceutical Activation of Nrf2 Accelerates Diabetic Wound Healing by Exosomes from Bone Marrow Mesenchymal Stem Cells
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Wang L, Cai Y, Zhang Q, Zhang Y
- KMID: 2529788
- Int J Stem Cells.
- 2022 May;15(2):164-172.
- doi: 10.15283/ijsc21067
Background and Objectives: Despite advances in wound treatments, chronic diabetic wounds remain a significant medi-cal challenge. Exosomes from mesenchymal stem cells (MSCs) and small molecule activators of nuclear factor erythroid... -
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- Effects and Mechanisms of Bone Marrow Mesenchymal Stem Cell Transplantation for Treatment of Ischemic Stroke in Hypertensive Rats
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Liu Y, Zhao Y, Min Y, Guo K, Chen Y, Huang Z, Long C
- KMID: 2529836
- Int J Stem Cells.
- 2022 May;15(2):217-226.
- doi: 10.15283/ijsc21136
Background and Objectives: Stroke is the most common cause of human death and functional disability, resulting in more than 5 million deaths worldwide each year. Bone marrow mesenchymal stem cells... -
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- Human Umbilical Cord Mesenchymal Stem Cells Improve the Necrosis and Osteocyte Apoptosis in Glucocorticoid-Induced Osteonecrosis of the Femoral Head Model through Reducing the Macrophage Polarization
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Tian G, Liu C, Gong Q, Yu Z, Wang H, Zhang D, Cong H
- KMID: 2529834
- Int J Stem Cells.
- 2022 May;15(2):195-202.
- doi: 10.15283/ijsc21120
Background and Objectives: Apoptosis is an outstanding determinant of glucocorticoid (GC)-induced osteonecrosis of the femoral head (ONFH). Human umbilical cord mesenchymal stem cells (hUC-MSCs) have been demonstrated to be associated... -
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- Evaluation of Circulating Endothelial Progenitor Cells in Abdominal Aortic Aneurysms after Endovascular Aneurysm Repair
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Wu W, Zhang J, Shao L, Huang H, Meng Q, Shen Z, Teng X
- KMID: 2529785
- Int J Stem Cells.
- 2022 May;15(2):136-143.
- doi: 10.15283/ijsc21027
Background and Objectives: Circulating endothelial progenitor cells (EPCs) participate in vascular repair and predict cardiovascular outcomes. The aim of this study was to investigate the correlation between EPCs and abdominal... -
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- Diesel Exhaust Particles Impair Therapeutic Effect of Human Wharton’s Jelly-Derived Mesenchymal Stem Cells against Experimental Colitis through ROS/ERK/cFos Signaling Pathway
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Park HS, Oh MK, Lee JW, Chae DH, Joo H, Kang JY, An HB, Yu A, Park JH, Yoo HM, Jung HJ, Choi U, Jung JW, Kim IS, Oh IH, Yu KR
- KMID: 2529835
- Int J Stem Cells.
- 2022 May;15(2):203-216.
- doi: 10.15283/ijsc21178
Background and Objectives: Epidemiological investigations have shown positive correlations between increased diesel exhaust particles (DEP) in ambient air and adverse health outcomes. DEP are the major constituent of particulate atmospheric... -
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