- Lo and Behold, the Lab-Grown Organs Have Arrived!
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Kim J
- KMID: 2526733
- Int J Stem Cells.
- 2022 Feb;15(1):1-2.
- doi: 10.15283/ijsc22026
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- Region Specific Brain Organoids to Study Neurodevelopmental Disorders
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Susaimanickam PJ, Kiral FR, Park IH
- KMID: 2526736
- Int J Stem Cells.
- 2022 Feb;15(1):26-40.
- doi: 10.15283/ijsc22006
Region specific brain organoids are brain organoids derived by patterning protocols using extrinsic signals as opposed to cerebral organoids obtained by self-patterning. The main focus of this review is to... -
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- A Simple Method for Generating Cerebral Organoids from Human Pluripotent Stem Cells
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Hong YJ, Lee Sb, Choi J, Yoon SH, Do JT
- KMID: 2526741
- Int J Stem Cells.
- 2022 Feb;15(1):95-103.
- doi: 10.15283/ijsc21195
Background and Objectives: In recent years, brain organoid technologies have been the most innovative advance in neural differentiation research. In line with this, we optimized a method to establish cerebral organoids... -
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- Engineering the Extracellular Matrix for Organoid Culture
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Heo JH, Kang D, Seo SJ, Jin Y
- KMID: 2526738
- Int J Stem Cells.
- 2022 Feb;15(1):60-69.
- doi: 10.15283/ijsc21190
Organoids show great potential in clinical translational research owing to their intriguing properties to represent a near physiological model for native tissues. However, the dependency of organoid generation on the... -
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- Direct Conversion to Achieve Glial Cell Fates: Oligodendrocytes and Schwann Cells
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Yun W, Kim YJ, Lee G
- KMID: 2526735
- Int J Stem Cells.
- 2022 Feb;15(1):14-25.
- doi: 10.15283/ijsc22008
Glia have been known for its pivotal roles in physiological and pathological conditions in the nervous system. To study glial biology, multiple approaches have been applied to utilize glial cells... -
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- Generation of Highly Expandable Intestinal Spheroids Composed of Stem Cells
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Kwon O, Kwon O, Yu WD, Yu WD, Son YS, Son YS, Jung KB, Jung KB, Lee H, Lee H, Son MY, Son MY
- KMID: 2526742
- Int J Stem Cells.
- 2022 Feb;15(1):104-111.
- doi: 10.15283/ijsc21209
Many of early findings regarding intestinal stem cells (ISCs) and their niche in the human intestine have relied on colorectal cancer cell lines and labor-intensive and time-consuming mouse models. However,... -
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- Engineering Brain Organoids: Toward Mature Neural Circuitry with an Intact Cytoarchitecture
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Jang H, Kim SH, Koh Y, Yoon KJ
- KMID: 2526737
- Int J Stem Cells.
- 2022 Feb;15(1):41-59.
- doi: 10.15283/ijsc22004
The emergence of brain organoids as a model system has been a tremendously exciting development in the field of neuroscience. Brain organoids are a gateway to exploring the intricacies of... -
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- Generation of Cortical Brain Organoid with Vascularization by Assembling with Vascular Spheroid
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Kook MG, Lee SE, Shin N, Kong D, Kim DH, Kim MS, Kang HK, Choi SW, Kang KS
- KMID: 2526740
- Int J Stem Cells.
- 2022 Feb;15(1):85-94.
- doi: 10.15283/ijsc21157
Background and Objectives: Brain organoids have the potential to improve our understanding of brain development and neurological disease. Despite the importance of brain organoids, the effect of vascularization on brain... -
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- From the Dish to the Real World: Modeling Interactions between the Gut and Microorganisms in Gut Organoids by Tailoring the Gut Milieu
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Park NY, Koh A
- KMID: 2526739
- Int J Stem Cells.
- 2022 Feb;15(1):70-84.
- doi: 10.15283/ijsc21243
The advent of human intestinal organoid systems has revolutionized the way we understand the interactions between the human gut and microorganisms given the host tropism of human microorganisms. The gut... -
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- Organoid Studies in COVID-19 Research
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Kim J, Koo BK, Clevers H
- KMID: 2526734
- Int J Stem Cells.
- 2022 Feb;15(1):3-13.
- doi: 10.15283/ijsc21251
The current COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has completely changed human life for more than two years. Upon the emergence of this new lethal... -
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