- IL-4/IL-13 Cytokine and Receptor in Asthma
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Yang ES
- KMID: 2314355
- Pediatr Allergy Respir Dis.
- 2005 Mar;15(1):1-11.
Asthma is a chronic allergic inflammatory disease of lung. The initiation and progression of asthma is dependent on the cytokines interleukin (IL) -4 and IL-13 acting through related receptor complexes.... -
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- Analysis of Cytokines in Sera from Type 1 Diabetic Patients at Diagnosis
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Yoon IS, Shin CH, Yang SW
- KMID: 1450618
- J Korean Soc Pediatr Endocrinol.
- 2011 Apr;16(1):13-19.
- doi: 10.6065/jkspe.2011.16.1.13
PURPOSE: Diverse cytokines influence the pathogenesis of type 1 diabetes mellitus (T1DM) in different ways. We studied the profile of cytokines in sera from type 1 diabetic patients at diagnosis. METHODS:... -
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- Studies on the Role of Interleukin-4 and Interleukin-13 in the Pathogenesis of Minimal Change Nephrotic Syndrome
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Cho BS
- KMID: 1989743
- Korean J Nephrol.
- 2001 May;20(3):375-380.
Minmal change nephrotic syndrome(MCNS) has been often associated with elevated IgE levels and referred to involve immune dysfunction. We have reported that MCNS may be a T-cell disorder involving abnormal... -
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- Sinensetin Inhibits Interleukin-6 in Human Mast Cell - 1 Via Signal Transducers and Activators of the Transcription 3 (STAT3) and Nuclear Factor Kappa B (NF-κB) Pathways
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Chae HS, Kim YM, Chin YW
- KMID: 2376491
- Nat Prod Sci.
- 2017 Mar;23(1):1-4.
- doi: 10.20307/nps.2017.23.1.1
Sinensetin, a pentamethoxyflavone, is known to exert various pharmacological activities including anti-angiogenesis, anti-diabetic and anti-inflammatory activities. However, its effects on the human mast cell - 1 (HMC-1) mediated inflammatory mechanism... -
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- Interleukin-4 Receptor Expression on Human Renal Cell Carcinoma Cell Lines by a Reverse Transcription-Polymerase Chain Reaction
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Cheon J, Chung DJ, Choi JB, Koh SK, Sohn JW
- KMID: 1913970
- Korean J Urol.
- 1995 Feb;36(2):121-127.
Recently interleukin-4 (IL-4) has been suggested to be a promising therapeutic agent for the malignant tumors of both murine and human origin. The effect of IL-4 is mediated by IL-4... -
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- Studies on the Determining Factors at Each Stage of Germinal Center B Cell Differentiation
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Choe JS, Choi YS
- KMID: 1550787
- Korean J Immunol.
- 1999 Jun;21(2):159-164.
To delineate the individual role of follicular dendritic cells (FDC) and T cells at each stage of GC B cell differentiation at the clonal level and to analyze the signals... -
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- Effects of L-ascorbic acid on the production of pro-inflammatory and anti-inflammatory cytokines in C57BL/6 mouse splenocytes
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Kong EH, Ma SY, Jeong JY, Kim KH
- KMID: 2308536
- Kosin Med J.
- 2015 Jun;30(1):41-49.
- doi: 10.7180/kmj.2015.30.1.41
OBJECTIVE: The imbalance between pro-inflammatory and anti-inflammatory cytokines may underlie different pain states. Although ascorbic acid is the most important physiological antioxidant that affects host defense mechanisms and immune homeostasis,... -
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- Studies on the role of interleukin-4 and Fc epsilon RII in the pathogenesis of minimal change nephrotic syndrome
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Cho BS, Lee CE, Pyun KH
- KMID: 1421936
- J Korean Med Sci.
- 1992 Dec;7(4):343-348.
- doi: 10.3346/jkms.1992.7.4.343
Childhood minimal change nephrotic syndrome (MCNS) has often been associated with allergic symptoms such as urticaria, bronchial asthma, atopic dermatitis, allergic rhinitis and elevated IgE levels and referred to... -
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- Essential roles for ID-1 motif of interleukin-4 receptor alpha chain in interleukin-4 signaling
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Youn J, Lee KH, Hwang WY, Paik DJ, Chung HS
- KMID: 2285854
- J Asthma Allergy Clin Immunol.
- 2003 Jun;23(2):372-384.
BACKGROUND: Interleukin (IL)-4 is a pleiotropic cytokine that plays an important role in the pathogenesis of the allergic inflammation and asthma. Upon IL-4 receptor (IL-4R) engagement, a variety of signaling... -
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- Moderate Exercise Enhances the Production of Interferon-γ and Interleukin-12 in Peripheral Blood Mononuclear Cells
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Zamani A, Salehi I, Alahgholi-Hajibehzad M
- KMID: 2383357
- Immune Netw.
- 2017 Jun;17(3):186-191.
- doi: 10.4110/in.2017.17.3.186
The purpose of this study was to explore the effect of two months moderate exercise on levels of IFN-γ, IL-12, IL-6 and IL-4 in serum and supernatants of in vitro... -
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- Association of Plasma Levels of Angiotensin-Converting Enzyme and Cytokines with Recurrent Depression : A Preliminary Study
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Sohn H, Lee SW, Kim MK, Lee KS, Lee SH, Kwon MS, Kim B
- KMID: 2371182
- Korean J Biol Psychiatry.
- 2017 Feb;24(1):39-44.
- doi: 10.0000/kjbp.2017.24.1.39
OBJECTIVES: Angiotensin-converting enzyme (ACE) gene and plasma levels of cytokines, such as tumor necrosis factor-α (TNF-α), interleukin-4 (IL-4), interleukin-6 (IL-6), interleukin-10 (IL-10), have previously been determined to be associated with... -
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- Expression of mRNA of GATA-3 and T-bet in the peripheral blood mononuclear cells of atopic asthmatics
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Jee YK, Kim YS, Park JS, Lee KY
- KMID: 2252688
- Korean J Med.
- 2004 Jan;66(1):67-74.
BACKGROUND: It is well known that the expression of Th2 cytokines are up-regulated in the atopic asthma. The study was to investigate the expression of transcription factors, such as GATA-3,... -
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- Determination and Significance of Serum Interleukin-18 Levels in Patients with Chronic Hepatitis B Virus Infection
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Yoon DY, Lee KA, Park JK, Kim JW
- KMID: 1730187
- Korean J Lab Med.
- 2004 Apr;24(2):139-145.
BACKGROUND: The aim of our study was to investigate the diagnostic value of interleukin-18 (IL-18) and other cytokines in chronic liver disease patients with hepatitis B virus (HBV), including chronic... -
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- Cytokine mRNA Expression in Mononuclear Cells from Lymph Nodes of Tuberculous Lymphadenitis Patients after In Vitro Stimulation with the TSP Antigen of Mycobacterium tuberculosis H37Rv
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Paik TH, Park JK, Kim HJ, Jo EK, Cho IH, Lim JH
- KMID: 2146934
- J Korean Soc Microbiol.
- 1998 Feb;33(1):15-26.
We isolated Triton X-100 solubilized protein (TSP) antigen which may be preferentially associated with the cell wall of M. tuberculosis. In this study, the proliferative activities and cytokine mRNA expression... -
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- STAT6 and PARP Family Members in the Development of T Cell-dependent Allergic Inflammation
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Krishnamurthy P, Kaplan MH
- KMID: 2349881
- Immune Netw.
- 2016 Aug;16(4):201-210.
- doi: 10.4110/in.2016.16.4.201
Allergic inflammation requires the orchestration of altered gene expression in the target tissue and in the infiltrating immune cells. The transcription factor STAT6 is critical in activating cytokine gene expression... -
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- Functional Changes of Interleukin-4 and Interferon-gamma of Peripheral Blood and Nasal Mucosa after Immunotherapy in Patients with Perennial Allergic Rhinitis
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Yeo SG, Cho JS, Jin YW, Cha CI, Kim KJ, Park KY
- KMID: 1874140
- Korean J Otolaryngol-Head Neck Surg.
- 1999 Jun;42(6):714-719.
BACKGROUND AND OBJECTIVES: Immunologic changes of immunotherapy can include reduced allergenstimulated mononuclear cells prolifer-ation and lymphokine production and the generation of allergic-specfic suppressor T cells. The changes and the relationships... -
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- Investigation of Cytokine Gene Polymorphisms in Korean Patients with Scrub Typhus
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Chang UI, Kim SY, Wie SH, Kim TG
- KMID: 2170277
- Infect Chemother.
- 2010 Feb;42(1):30-34.
- doi: 10.3947/ic.2010.42.1.30
BACKGROUND: Scrub typhus is caused by Orientia tsutsugamushi and can become severe and potentially life-threatening. It is suggested that specific host factors can modify the host response during O. tsutsugamushi... -
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- Immunologic Response to Mistletoe Extract (Viscum album L.) after Conventional Treatment in Patients with Operable Breast Cancer
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Son GS, Ryu WS, Kim HY, Woo SU, Park KH, Bae JW
- KMID: 2286554
- J Breast Cancer.
- 2010 Mar;13(1):14-18.
- doi: 10.4048/jbc.2010.13.1.14
PURPOSE: To reduce the side effects and improve the effectiveness of standard chemoradiation therapy, many complementary or alternative medicines have been tried. However, little is known about its immunologic effects... -
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- Circulating Cytokine Levels and Changes During the Treatment in Patients with Active Tuberculosis in Korea
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Ryu YJ, Kim YJ, Kwon JM, Na YJ, Jung YJ, Seoh JY, Cheon SH
- KMID: 1516633
- Tuberc Respir Dis.
- 2003 Aug;55(2):140-153.
- doi: 10.4046/trd.2003.55.2.140
BACKGROUND: The cell-mediated immune reaction to tuberculosis infection involves a complex network of cytokines. The extent of inflammation, tissue damage and severity of the disease suggested to be determined by... -
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- Inhibition of Murine Allergic Response by Monoclonal Interleukin-4 Receptor Antibody
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Lee CH, Yun JB, Rhee CS, Park SW, Kim JW
- KMID: 2131777
- J Rhinol.
- 2000 Nov;7(2):149-153.
BACKGROUND AND OBJECTIVES: Several strategies were used to control the IgE production by interfering the functional activities of IL-4. However, most of them revealed limited effects to reduction of allergic... -
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