- Regulation of Osteoclast Differentiation by Cytokine Networks
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Amarasekara DS, Yun H, Kim S, Lee N, Kim H, Rho J
- KMID: 2404891
- Immune Netw.
- 2018 Feb;18(1):e8.
- doi: 10.4110/in.2018.18.e8
Cytokines play a pivotal role in maintaining bone homeostasis. Osteoclasts (OCs), the sole bone resorbing cells, are regulated by numerous cytokines. Macrophage colony-stimulating factor and receptor activator of NF-κB ligand... -
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- Effects of Thyroid Hormone on Preduction of Interleukin-6 and Interleukin-11 in Human Bone Marrow Stromal Cells
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Kim CH, Kim DK, Kim HK, Song YK, Kim KS
- KMID: 2331083
- J Korean Soc Endocrinol.
- 1997 Dec;12(4):557-564.
BACKGROUND: It is well known that excessive thyroid hormone in the body is associated with bone loss. However, the mechanism by which thyroid hormone affects bone cell metabolism remains unclear.... -
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- In Vitro Effect of Interleukin-11 (IL-11) on Megakaryopoiesis from Umbilical Cord Blood Cells
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Lee KK, Kim CK, Lee NS, Kim SJ, Cheong HJ, Lee KT, Park SK, Baick SH, Won JH, Hong DS, Park HS
- KMID: 2167970
- Immune Netw.
- 2003 Mar;3(1):47-52.
- doi: 10.4110/in.2003.3.1.47
BACKGROUND: The megakaryopoiesis and platelet production is regulated by several hematopoietc factors such as thrombopoietin (TPO), interleukin-11 (IL-11) and interleukin-3 (IL-3). IL-11 is a potent stimulator of megakaryopoiesis in vivo,... -
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- Inhibition of the Interleukin-11-STAT3 Axis Attenuates Hypoxia-Induced Migration and Invasion in MDA-MB-231 Breast Cancer Cells
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Lim JH
- KMID: 2285537
- Korean J Physiol Pharmacol.
- 2014 Oct;18(5):391-396.
- doi: 10.4196/kjpp.2014.18.5.391
Although interleukin-11 (IL-11) has been reported to be elevated in hypoxic tumors and has been associated with a poor prognosis in various cancers, little is known about its precise role... -
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- Relationship between Atopic Status and Immunoregulatory Cytokines in Respiratory Syncytial Virus Bronchiolitis
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Yang BS, Kim SY, Lee GH, Lee JH, Choi EJ, Kim JK, Kim SG, Kim WT, Chung HL
- KMID: 2314307
- Pediatr Allergy Respir Dis.
- 2004 Mar;14(1):30-37.
PURPOSE: Recent studies have demonstrated and suggested that Interleukin (IL) -10 and IL-11 are implicated in the pathophysiology of RSV infection and may act in the regulation of inflammatory response.... -
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- Lysophosphatidic acid enhances breast cancer cells-mediated osteoclastogenesis
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Nam JS, Sharma AR, Nguyen LT, Jagga S, Lee YH, Sharma G, Lee SS
- KMID: 2419000
- Korean J Physiol Pharmacol.
- 2018 Sep;22(5):503-511.
- doi: 10.4196/kjpp.2018.22.5.503
Lysophosphatidic acid (LPA) is known to play a critical role in breast cancer metastasis to bone. In this study, we tried to investigate any role of LPA in the regulation... -
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- Change of Platelet Count and Mean Platelet Volume after Intravenous Immunoglobulin Injection in Acute Idiopathic Thrombocytopenic Purpura
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Jeon IS, Kim JS, Im HJ
- KMID: 2037382
- Korean J Pediatr Hematol Oncol.
- 2004 Apr;11(1):1-6.
PURPOSE: The platelet synthesis is extremely variable after intravenous immunoglogulin injection (IVIG) in acute idiopathic thrombocytopenic purpura (ITP). To investigate the size variation of platelet according to the time sequence... -
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- The Correlation between Increased Serum Concentrations of Interleukin-6 Family Cytokines and Disease Activity in Rheumatoid Arthritis Patients
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Chung SJ, Kwon YJ, Park MC, Park YB, Lee SK
- KMID: 1106445
- Yonsei Med J.
- 2011 Jan;52(1):113-120.
- doi: 10.3349/ymj.2011.52.1.113
PURPOSE: This study was performed to determine whether the serum concentrations of interleukin (IL)-6 family cytokines are elevated in patients with rheumatoid arthritis (RA) and to investigate the relationship between... -
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- IL-11, IFN-gamma and ECP levels in nasopharyngeal secretions from non-asthmatic wheezing children with respiratory syncytial virus or influenza A virus infections
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Oh JW, Lee HB, Park IK, Kang JO
- KMID: 1563369
- J Asthma Allergy Clin Immunol.
- 2000 Feb;20(1):85-91.
BACKGROUND: Infection with respiratory virus has been shown to exacerbate asthma in humans. However, the role of a respiratory virus in the pathogenesis of chronic asthma and/or wheezing in young... -
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- Factors affecting Osteoclast Formation
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Chang JS, Park JH, Kim JH, Kim KY
- KMID: 2199183
- J Korean Orthop Res Soc.
- 1998 Oct;1(2):212-222.
Recently many kinds of osteotropic factors and cytokines were identified to be acting in the process of the osteoclast formation. However, their reported effects were so variable that it is... -
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- Cancer-Associated Fibroblasts Promote the Chemo-resistance in Gastric Cancer through Secreting IL-11 Targeting JAK/STAT3/Bcl2 Pathway
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Ma J, Song X, Xu X, Mou Y
- KMID: 2437613
- Cancer Res Treat.
- 2019 Jan;51(1):194-210.
- doi: 10.4143/crt.2018.031
PURPOSE: Our aim was to detect the potential role of interleukin 11 (IL-11) in the development of chemo-resistance in gastric cancer and to reveal the mechanism involved in the process. MATERIALS... -
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- Increased PMA-stimulated Release of MMP-9 and TGF-beta1 in the Plasma of Children with Persistent Asthma
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- KMID: 2299667
- Korean J Asthma Allergy Clin Immunol.
- 2005 Sep;25(3):200-204.
BACKGROUND: The contribution of matrix metalloproteinase (MMP)-9 to the pathogenesis of asthma has been reported. Transforming growth factor (TGF)-beta1 and interleukin (IL)- 11, and -17 are profibrotic cytokines which increase... -
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- Inhibitors of DNA methylation support TGF-β1-induced IL11 expression in gingival fibroblasts
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Sufaru IG, Beikircher G, Weinhaeusel A, Gruber R
- KMID: 2377741
- J Periodontal Implant Sci.
- 2017 Apr;47(2):66-76.
- doi: 10.5051/jpis.2017.47.2.66
PURPOSE: Oral wound healing requires gingival fibroblasts to respond to local growth factors. Epigenetic silencing through DNA methylation can potentially decrease the responsiveness of gingival fibroblasts to local growth factors.... -
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- Gene expression profiling in human dental pulp cells treated with mineral trioxide aggregate
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Kim YB, Shon WJ, Lee W, Kum KY, Baek SH, Bae KS
- KMID: 2294341
- J Korean Acad Conserv Dent.
- 2010 May;35(3):152-163.
- doi: 10.5395/JKACD.2010.35.3.152
This study investigated the changes in gene expression when mineral trioxide aggregate (MTA) was applied in vitro to human dental pulp cells (HDPCs). MTA in a teflon tube (diameter 10... -
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- Comparison of gene expression profiles of human dental pulp cells treated with mineral trioxide aggregate and calcium hydroxide
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Kim YB, Shon WJ, Lee W, Kum KY, Baek SH, Bae KS
- KMID: 2176577
- J Korean Acad Conserv Dent.
- 2011 Sep;36(5):397-408.
- doi: 10.5395/JKACD.2011.36.5.397
OBJECTIVES: This study investigated changes in gene expressions concerning of differentiation, proliferation, mineralization and inflammation using Human-8 expression bead arrays when white Mineral Trioxide Aggregate and calcium hydroxide-containing cement were... -
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