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Detection of Integrons and Staphylococcal Cassette Chromosome mec Types in Clinical Methicillin-resistant Coagulase Negative Staphylococci Strains

Hajiahmadi F, Ghale ES, Alikhani M, Mordadi A, Arabestani MR

OBJECTIVES: Integrons are thought to play an important role in the spread of antibiotic resistance. This study investigates class 1 and 2 integron-positive methicillin-resistant coagulase-negative staphylococci strains isolated in Iran...
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The Role of Integrons in the Spread of Multi-drug Resistance

Jang SJ

  • KMID: 2224686
  • Korean J Clin Microbiol.
  • 2005 Apr;8(1):1-9.
The liberal use of antibiotics in human medicine and animal husbandry has promoted the spread of multiple antibiotic resistance. Molecular mechanisms for the acquisition of resistance genes by integron-mediated recombination...
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Antimicrobial Resistance and Integrons Found in Commensal Escherichia coli Isolates from Healthy Humans

Lee JC, Kang HY, Oh JY, Jeong JH, Seol SY, Cho DT, Kim J, Lee YC

The emergence and spread of antimicrobial resistance among the pathogenic and commensal Enterobacteriaceae are of great concern worldwide. We characterized the antimicrobial resistance and integrons found in commensal Escherichia coli...
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Diversity of Integrons Carrying blaVIM-2 Cassette in Pseudomonas spp. and Acinetobacter spp.

Yum J, Shin HB, Yong D, Chong Y

BACKGROUND: Metallo-beta-lactamase-mediated carbapenem resistance has been increasingly reported in Pseudomonas, Acinetobacter and other Gram-negative bacilli (GNB) in many countries. A few studies showed highly variable structure of MBL-gene cassette-carrying integrons....
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Integron Carriage in Multiresistant Acinetobacter baumannii Strains

Oh JY, Lee JC

  • KMID: 2054967
  • J Bacteriol Virol.
  • 2003 Dec;33(4):245-251.
One hundred and eight Acinetobacter baumannii strains isolated from three university hospitals in Korea were investigated for the presence of integrons and its correlation with multiple antibiotic resistance. A. baumannii...
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Analysis of Integrons and Antimicrobial Resistances of Multidrug Resistant Escherichia coli Isolated in Korea

Yang YY, Suh MH

Antibacterial drugs are one of the most important therapeutic agents of bacterial infections but multidrug resistant Escherichia coli (MDREC) is an increasing problem worldwide. Major resistance mechanism of MDREC is...
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Epidemiological Characterizations of Class 1 Integrons from Multidrug-Resistant Acinetobacter Isolates in Daejeon, Korea

Sung JY, Koo SH, Kim S, Kwon KC

BACKGROUND: Multidrug-resistant (MDR) Acinetobacter spp. acquire antimicrobial agent-resistance genes via class 1 integrons. In this study, integrons were characterized to investigate the antimicrobial resistance mechanisms of MDR Acinetobacter isolates. In...
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Integron and mobile Gene Cassettes

Lee K, Chong Y

  • KMID: 1892737
  • Korean J Clin Microbiol.
  • 2000 Sep;3(2):83-88.
No abstract available.
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Detection and Characterization of Integrons in Nontyphoid Salmonella Clinical Isolates

Lee JE, Park SJ, Kim SH, Kim MN, Lee NY, Lee BK, Lee SO, Kim YS, Woo JH, Choi SH

BACKGROUND: Nontyphoid Salmonella (NTS) is a leading cause of human food-borne enteritiS. It has been known that integron, a naturally occurring gene capture and expression element, plays an important role...
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Characterization of Class 1 Integrons in Metallo-beta-lactamase-producing Pseudomonas aeruginosa

Sung JY, Koo SH, Kwon KC, Park JW, Ko CS, Shin SY, Song JH

BACKGROUND: The genes of metallo-beta-lactamase (MBL), a powerful carbapenemase, are carried as a part of the mobile gene cassettes inserted into integrons playing an important role in rapid dissemination of...
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Changes in patterns of antimicrobial susceptibility and class 1 integron carriage among Escherichia coli isolates

Kang SG, Lee DY, Shin SJ, Ahn JM, Yoo HS

  • KMID: 1091200
  • J Vet Sci.
  • 2005 Sep;6(3):201-205.
The worldwide use of antimicrobials in different fields has created enormous pressure for the selection of resistance among opportunistic bacterial pathogen. One hundred four E. coli isolates were collected and...
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The sul1 Gene in Stenotrophomonas maltophilia With High-Level Resistance to Trimethoprim/Sulfamethoxazole

Chung HS, Kim K, Hong SS, Hong SG, Lee K, Chong Y

Emerging resistance to trimethoprim/sulfamethoxazole (SXT) poses a serious threat to the treatment of Stenotrophomonas maltophilia infections. We determined the prevalence and molecular characteristics of acquired SXT resistance in recent clinical...
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Molecular Epidemiology of Integron-Associated Antimicrobial Gene Cassettes in the Clinical Isolates of Acinetobacter baumannii from Northern Taiwan

Lin MF, Liou ML, Tu CC, Yeh HW, Lan CY

BACKGROUND: The aims of this study were to understand the molecular epidemiology of integron-associated gene cassettes in Acinetobacter baumannii across four hospitals in northern Taiwan and to clarify the relationship...
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Antimicrobial Resistance Determinants in Imipenem-nonsusceptible Acinetobacter calcoaceticus-baumannii Complex Isolated in Daejeon, Korea

Sung JY, Kwon KC, Cho HH, Koo SH

BACKGROUND: Members of the Acinetobacter calcoaceticus-baumannii (Acb) complex are important opportunistic bacterial pathogens and present significant therapeutic challenges in the treatment of nosocomial infections. In the present study, we investigated...
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Genetic Basis of Multidrug-resistant Acinetobacter baumannii Clinical Isolates from Three University Hospitals in Chungcheong Province, Korea

Koo SH, Kwon KC, Cho HH, Sung JY

BACKGROUND: The emergence of multidrug-resistant (MDR) Acinetobacter baumannii as an important opportunistic pathogen has given rise to significant therapeutic challenges in the treatment of nosocomial infections. In the present study,...
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Multidrug-resistant Acinetobacter baumannii infection in intensive care unit patients in a hospital with building construction: is there an association?

Kamalbeik , Talaie H, Mahdavinejad A, Karimi A, Salimi A

BACKGROUND: Acinetobacter baumannii (A. baumannii) has emerged globally as a significant pathogen in hospitals. It is also present in soil and water. In a previous study, we discovered that the...
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Phenotypic and genotypic antimicrobial resistance and virulence genes of Salmonella enterica isolated from pet dogs and cats

Srisanga S, Angkititrakul S, Sringam P, Le Ho PT, Vo AT, Chuanchuen R

Salmonella enterica isolates (n = 122), including 32 serotypes from 113 dogs and 9 cats, were obtained from household dogs (n = 250) and cats (n = 50) during 2012–2015....
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Epidemiology and Characteristics of Metallo-beta-Lactamase-Producing Pseudomonas aeruginosa

Hong DJ, Bae IK, Jang IH, Jeong SH, Kang HK, Lee K

Metallo-beta-lactamase-producing Pseudomonas aeruginosa (MPPA) is an important nosocomial pathogen that shows resistance to all beta-lactam antibiotics except monobactams. There are various types of metallo-beta-lactamases (MBLs) in carbapenem-resistant P. aeruginosa including...
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Genotypic Diversity of Multidrug Resistant Shigella species from Iran

Zamanlou S, Rezaee MA, Aghazadeh , Ghotaslou , Nave HH, Khalili Y

BACKGROUND: In many developing countries, shigellosis is endemic and also occurs in epidemics and treatment of multidrug-resistant (MDR) isolates are important. The aims of this study were to determine the...
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Class 1 Integron Carriage in Extended-spectrum beta-lactamase-producing K. pneumoniae

Kim J

  • KMID: 1963266
  • J Bacteriol Virol.
  • 2004 Sep;34(3):181-189.
Many antibiotic resistance genes found in gram-negative clinical isolates are a part of a gene cassette inserted into an integron. Incidence of the integron carriage in extended-spectrum beta-lactamases (ESBLs)-producing clinical...
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