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Independent Correlation of the C1–2 Cobb Angle With Patient-Reported Outcomes After Correcting Chronic Atlantoaxial Instability

Pan Z, Xi Y, Huang W, Kim KN, Yi S, Shin DA, Huang K, Chen Y, Huang Z, He D, Ha Y

OBJECTIVE: To investigate three-planar radiographic results and patient-reported outcomes (PROs) after correcting chronic atlantoaxial instability (AAI) by translaminar screw (TLS) and pedicle screw (PS) fixation, and to explore the potential...
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The Progress and Clinical Application of Breast Cancer Organoids

Yu J, Huang W

Breast cancer is the malignant tumor with the highest incidence in women. Nowadays, the objects in vitro of models of this disease are mainly from breast cancer cell lines and...
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2019 Novel Coronavirus (COVID-19) Pneumonia withHemoptysis as the Initial Symptom: CT and ClinicalFeatures

Shi F, Yu Q, Huang W, Tan C

Recently, some global cases of 2019 novel coronavirus (COVID-19) pneumonia have been caused by second- or third-generation transmission of the viral infection, resulting in no traceable epidemiological history. Owing to the...
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The Efficacy of Continuous Positive Airway Pressure Therapy on Nocturia in Patients With Obstructive Sleep Apnea: A Systematic Review and Meta-Analysis

Wang T, Huang W, Zong H, Zhang Y

PURPOSE: To assess the efficacy of the continuous positive airway pressure (CPAP) on nocturia in patients with obstructive sleep apnea (OSA). METHODS: A literature review was performed to identify all published...
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A Prospective Pilot Study Investigating Performance of 18F‑Fluciclovine PET Imaging for Detection of Prostate Cancer 2 Years Following Primary Partial Gland Cryoablation

Nazemi A, Huang W, Wysock J, Taneja S, Friedman K, Gogaj R, Lepor H

Purpose The goal of partial gland ablation (PGA) is to eradicate focal lesions of clinically significant prostate cancer (csPCa) with minimal adverse impact on functional outcomes. The primary objective of...
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Curcumin attenuates renal ischemia reperfusion injury via JNK pathway with the involvement of p300/CBP-mediated histone acetylation

Yang L, Chen X, Bi Z, Liao J, Zhao W, Huang W

Apoptosis is proved responsible for renal damage during ischemia/reperfusion. The regulation for renal apoptosis induced by ischemia/reperfusion injury (IRI) has still been unclearly characterized to date. In the present study,...
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The Role of Neutrophil-to-Lymphocyte Ratio in Predicting Pathological Response for Resectable Non–Small Cell Lung Cancer Treated with Neoadjuvant Chemotherapy Combined with PD-1 Checkpoint Inhibitors

Sun X, Feng Y, Zhang B, Huang W, Zhao X, Zhang H, Yue D, Wang C

Purpose The aim of our study was to investigate the value of baseline and preoperative neutrophil-to-lymphocyte ratio (NLR) in predicting the pathological response and disease-free survival (DFS) of neoadjuvant chemotherapy alone...
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Hypoxic Pretreatment of Adipose-Derived Stem Cells Accelerates Diabetic Wound Healing via circ-Gcap14 and HIF-1α/VEGF Mediated Angiopoiesis

Wang Z, Feng C, Liu H, Meng T, Huang W, Long X, Wang X

Background and Objectives: Adipose-derived stem cell (ADSC) transplantation improves stem cell paracrine function and can enhance wound healing. However, in diabetic patients, glucose-associated effects on this function and cell survival...
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Inhibition of lncRNA KCNQ1OT1 Improves Apoptosis and Chemotherapy Drug Response in Small Cell Lung Cancer by TGF-β1 Mediated Epithelial-to-Mesenchymal Transition

Li D, Tong Q, Lian Y, Chen Z, Zhu Y, Huang W, Wen Y, Wang Q, Liang S, Li M, Zheng J, Liu Z, Liu H, Guo L

Purpose Drug resistance is one of the main causes of chemotherapy failure in patients with small cell lung cancer (SCLC), and extensive biological studies into chemotherapy drug resistance are required....
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Efficacy and Safety of Tension-Free Vaginal Tape-Secur Mini-Sling Versus Standard Midurethral Slings for Female Stress Urinary Incontinence: A Systematic Review and Meta-Analysis

Huang W, Wang T, Zong H, Zhang Y

PURPOSE: To assess the efficacy and safety of tension-free vaginal tape (TVT)-Secur for stress urinary incontinence (SUI). METHODS: A literature review was performed to identify all published trials of TVT-Secur. The...
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Cervical Cancer Screening Rate and Willingness among Female Migrants in Shenzhen, China: Three-Year Changes in Citywide Surveys

Lin W, Chen B, Wu B, Yuan S, Zhong C, Huang W, Hu H, Liu Z, Wang Y

Purpose This study attempted to detect the changes of cervical cancer screening rate and willingness among female migrants, and the associated socio-demographic factors in Shenzhen city. Materials and Methods Two citywide...
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The Prediction Analysis of Autistic and Schizotypal Traits in Attentional Networks

Huang W, Zhang L, Sun Y, Chen F, Wang K

Objective Empirical findings confirmed that autistic and schizotypal traits are associated with attentional function as well as include various dimensions. So far, no study has reported which dimension of these...
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Glutamine Synthetase Induced Spinal Seizures in Rats

Shin DW, Yoon YS, Matsumoto , Huang W, Ceraulo P, Young W

Glutamine synthetase (GS) is a key enzyme in the regulation of glutamate neurotransmission in the central nervous system. It is responsible for converting glutamate to glutamine, consuming one ATP and...
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p53 Promotes Differentiation of Cardiomyocytes from hiPSC through Wnt Signaling-Mediated Mesendodermal Differentiation

Liu Y, Zhang P, Huang W, Liu F, Long D, Peng W, Dang X, Zeng X, Zhou R

Background and Objectives: Manipulating different signaling pathways via small molecules could efficiently induce cardiomyocytes from human induced pluripotent stem cells (hiPSC). However, the effect of transcription factors on the hiPSC-directed cardiomyocytes...
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The Biphasic Effect of Retinoic Acid Signaling Pathway on the Biased Differentiation of Atrial-like and Sinoatrial Node-like Cells from hiPSC

Liu F, Long D, Huang W, Peng W, Lan H, Zhou Y, Dang X, Zhou R

Background and Objectives: Although human-induced pluripotent stem cells (hiPSC) can be efficiently differentiated into cardiomyocytes (CMs), the heterogeneity of the hiPSC-CMs hampers their applications in research and regenerative medicine. Retinoic...
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Establishment of the Lunar Phase Morphological Classification for Cervical Spinal Canal

Cui Z, Wang H, Sun Y, Huang W, Zou F, Ma X, Lyu F, Jiang J, Wang H

Study Design: Retrospective clinical trial. Purpose: To establish a morphological classification of the cervical spinal canal using its parameters. Overview of Literature: Cervical spine computed tomography (CT) data of 200 healthy volunteers...
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White Matter Microstructural Similarity and Diversity of Functional Constipation and Constipation-predominant Irritable Bowel Syndrome

Nan J, Zhang L, Chen Q, Zong N, Zhang P, Ji X, Ma S, Zhang Y, Huang W, Du Z, Xia Y, Zhang M

  • KMID: 2417278
  • J Neurogastroenterol Motil.
  • 2018 Jan;24(1):107-118.
  • doi: 10.5056/jnm17038
BACKGROUND/AIMS: The Rome III criteria separated chronic constipation into functional constipation (FC) and constipation-predominant irritable bowel syndrome (IBS-C), but some researchers questioned the partitioning and treated both as distinct parts...
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Commutability Assessment of Candidate External Quality Assessment Materials for Aminotransferase Activity Measurements Based on Different Approaches in China

Long Q, Qi T, Zhang T, Wang J, Zeng J, Yan Y, Wang M, Huang W, Zhao H, Chen W, Zhang C

Background: Using commutable external quality assessment (EQA) materials is important for monitoring successful harmonization efforts. We assessed the commutability of four human serum pool (HSP) preparations to identify candidate EQA...
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Early Diagnosis and Management of Cerebral Venous Flow Obstruction Secondary to Transsinus Fracture after Traumatic Brain Injury

Wang WH, Lin JM, Luo F, Hu LS, Li J, Huang W

BACKGROUND AND PURPOSE: Cerebral venous flow obstruction (CVFO) is a fatal complication of traumatic brain injury. To compare the outcomes of patients with CVFO secondary to traumatic-brain-injury-induced transsinus fracture who...
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COVID Pandemic Impact on Healthcare Provision and Patient Psychosocial Distress: A Multi-National Cross-Sectional Survey among Asia-Pacific Countries

Chung E, Jiann BP, Nagao K, Hakim L, Huang W, Lee J, Lin H, Tien Mai DB, Nguyen Q, Park HJ, Sato Y, Tantiwongse K, Yuan Y, Park K

Purpose: COVID pandemic significantly affected the delivery and maintenance of healthcare system, resulting in greater utilization of digital health interventions. Materials and Methods: This multi-national cross-sectional survey was administered to clinicians...
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