- A case of central pontine and extrapontine myelinolysis with early hypermetabolism on 18FDG-PET scan
-
Roh JK, Nam H, Lee MC
- KMID: 1107236
- J Korean Med Sci.
- 1998 Feb;13(1):99-102.
- doi: 10.3346/jkms.1998.13.1.99
We report a 63 year-old woman who developed central pontine and extrapontine myelinolysis after rapid correction of hyponatremia. Lesions on brain MRI showed hypermetabolism on 18FDG-PET scan in the early... -
- CITED
-
- Close
- SHARE
-
- Close
- Effect of the combination of metformin and fenofibrate on glucose homeostasis in diabetic Goto-Kakizaki rats
-
Oh TJ, Shin JY, Kang GH, Park KS, Cho YM
- KMID: 2154249
- Exp Mol Med.
- 2013 Jul;45(7):e30.
Metformin has been reported to increase the expression of the glucagon-like peptide-1 (GLP-1) receptor in pancreatic beta cells in a peroxisome proliferator-activated receptor (PPAR)-alpha-dependent manner. We investigated whether a PPARalpha... -
- CITED
-
- Close
- SHARE
-
- Close
- A Protective Role for Heme Oxygenase-1 in INS-1 Cells and Rat Islets that are Exposed to High Glucose Conditions
-
Won KC, Moon JS, Eun MJ, Yoon JS, Chun KA, Cho IH, Kim YW, Lee HW
- KMID: 1778421
- J Korean Med Sci.
- 2006 Jun;21(3):418-424.
- doi: 10.3346/jkms.2006.21.3.418
Heme oxygenase-1 (HO-1) has been described as an inducible protein that is capable of cytoprotection via radical scavenging and the prevention of apoptosis. Chronic exposure to hyperglycemia can lead to... -
- CITED
-
- Close
- SHARE
-
- Close
- Regulation of Type IV Collagen alpha Chains of Glomerular Epithelial Cells in Diabetic Conditions
-
Ha TS, Hong EJ, Ahn EM, Ahn HY
- KMID: 1782003
- J Korean Med Sci.
- 2009 Oct;24(5):837-843.
- doi: 10.3346/jkms.2009.24.5.837
An early feature of diabetic nephropathy is the alteration of the glomerular basement membrane (GBM), which may result in microalbuminuria, subsequent macroproteinuria, and eventual chronic renal failure. Although type IV... -
- CITED
-
- Close
- SHARE
-
- Close
- Characterization of regulatory elements on the promoter region of human ATP-citrate lyase
-
Moon YA, Kim KS, Cho UH, Yoon DJ, Park SW
- KMID: 1029940
- Exp Mol Med.
- 1999 Jun;31(2):108-114.
ATP-citrate lyase (ACL), an enzyme catalyzing the first step in biosynthesis of fatty acids, is induced during the lipogenesis and cholesterologenesis. We demonstrate that the region -213 to -128 of human ACL... -
- CITED
-
- Close
- SHARE
-
- Close
- Increased glycosylation of human lens epithelial basement membrane in diabetes mellitus
-
Shin DH, Mandel SS, Lee JH, Ernst B, Newman BL, Juzych M
- KMID: 1735118
- Korean J Ophthalmol.
- 1994 Jun;8(1):26-31.
- doi: 10.3341/kjo.1994.8.1.26
We studied the nonenzymatic glycosylation of lens epithelial basement membranes (LEBM) of senile cataractous lenses of both diabetic and nondiabetic patients. The human LEBMs were isolated from surgically removed senile... -
- CITED
-
- Close
- SHARE
-
- Close
- Effect of peritoneal glucose load on plasma leptin concentration in continuous ambulatory peritoneal dialysis patients
-
Kim MJ, Kim GA, Lee SW, Song JH, Hyun IY
- KMID: 1067114
- Yonsei Med J.
- 2000 Aug;41(4):485-490.
- doi: 10.3349/ymj.2000.41.4.485
This study was performed to investigate the effect of peritoneal glucose load on plasma leptin concentrations in the continuous ambulatory peritoneal dialysis (CAPD) performed on 13 non-diabetic ESRD patients. Plasma... -
- CITED
-
- Close
- SHARE
-
- Close
- Effect of hypothermia on brain cell membrane function and energy metabolism after transient global hypoxia-ischemia in the newborn piglet
-
Park WS, Chang YS, Lee MH
- KMID: 1129907
- J Korean Med Sci.
- 2001 Jun;16(3):335-341.
- doi: 10.3346/jkms.2001.16.3.335
This study was done to determine the effects of hypothermia on brain cell membrane function and energy metabolism after transient hypoxia-ischemia (HI) in the newborn piglet. Cerebral HI was induced... -
- CITED
-
- Close
- SHARE
-
- Close
- Reduced dihydroxyacetone sensitivity and normal sensitivity to glyceraldehyde and oxidizing agent of ATP-sensitive K+ channels of pancreatic beta cells in NIDDM rats
-
Song DK, Park WK, Bae JH, Park MK, Kim SJ, Ho WK, Earm YE
- KMID: 1081048
- J Korean Med Sci.
- 1997 Aug;12(4):286-292.
- doi: 10.3346/jkms.1997.12.4.286
The inhibition of ATP-sensitive K+(KATP) channels in pancreatic beta cells is a key step of insulin secretion induced by glucose. Glucose-induced insulin secretion from the beta cells is selectively... -
- CITED
-
- Close
- SHARE
-
- Close
- Effects of 4 Weeks Recombinant Human Growth Hormone Administration on Insulin Resistance of Skeletal Muscle in Rats
-
Park MJ, Jung SR, Jung HL, Craig BW, Lee CD, Kang HY
- KMID: 1782951
- Yonsei Med J.
- 2008 Dec;49(6):1008-1016.
- doi: 10.3349/ymj.2008.49.6.1008
PURPOSE: Effect of recombinant human growth hormone (rhGH) administration on lipid storage, and its subsequent effect on insulin sensitivity have not yet been adequately examined. Thus, we investigated the effects... -
- CITED
-
- Close
- SHARE
-
- Close
- Relations between Long-term Glycemic Control and Postoperative Wound and Infectious Complications after Total Knee Arthroplasty in Type 2 Diabetics
-
Han HS, Kang SB
- KMID: 1705532
- Clin Orthop Surg.
- 2013 Jun;5(2):118-123.
- doi: 10.4055/cios.2013.5.2.118
BACKGROUND: The authors examined whether poor preoperative glucose control, as indicated by the hemoglobin A1c (HbA1c) level of more than 8%, is associated with postoperative wound and infectious complications in... -
- CITED
-
- Close
- SHARE
-
- Close
- Rac-mediated actin remodeling and myosin II are involved in KATP channel trafficking in pancreatic beta-cells
-
Han YE, Lim A, Park SH, Chang S, Lee SH, Ho WK
- KMID: 2160621
- Exp Mol Med.
- 2015 Oct;47(10):e190.
- doi: 10.1038/emm.2015.72
AMP-activated protein kinase (AMPK) is a metabolic sensor activated during metabolic stress and it regulates various enzymes and cellular processes to maintain metabolic homeostasis. We previously reported that activation of... -
- CITED
-
- Close
- SHARE
-
- Close
- Effects of decreased cerebral perfusion pressure on cerebral hemodynamics, brain cell membrane function and energy metabolism during the early phase of experimental Escherichia coli meningitis in the newborn piglet
-
Park WS, Chang YS
- KMID: 648125
- J Korean Med Sci.
- 2000 Apr;15(2):203-210.
- doi: 10.3346/jkms.2000.15.2.203
In this study, we tested the hypothesis that decreased cerebral perfusion pressure (CPP) induces cerebral ischemia and worsen brain damage in neonatal bacterial meningitis. Meningitis was induced by intracisternal injection... -
- CITED
-
- Close
- SHARE
-
- Close
- Adiponectin and thiazolidinedione targets CRTC2 to regulate hepatic gluconeogenesis
-
Yoon YS, Ryu D, Lee MW, Hong S, Koo SH
- KMID: 1119323
- Exp Mol Med.
- 2009 Aug;41(8):577-583.
- doi: 10.3858/emm.2009.41.8.063
During fasting periods, hepatic glucose production is enhanced by glucagon to provide fuels for other organs. This process is mediated via cAMP-dependent induction of the CREB regulated transcriptional coactivator (CRTC)... -
- CITED
-
- Close
- SHARE
-
- Close
- The Neuroradiological Findings of Children with Developmental Language Disorder
-
Im SH, Park ES, Kim DY, Song DH, Lee JD
- KMID: 724094
- Yonsei Med J.
- 2007 Jun;48(3):405-411.
- doi: 10.3349/ymj.2007.48.3.405
PURPOSE: To investigate the general characteristics of glucose metabolism distribution and the functional deficit in the brain of children with developmental language delay (DLD), we compared functional neuroradiological studies such... -
- CITED
-
- Close
- SHARE
-
- Close
- Simulation of Oral Glucose Tolerance Tests and the Corresponding Isoglycemic Intravenous Glucose Infusion Studies for Calculation of the Incretin Effect
-
Kim M, Oh TJ, Lee JC, Choi K, Kim MY, Kim HC, Cho YM, Kim S
- KMID: 1734925
- J Korean Med Sci.
- 2014 Mar;29(3):378-385.
- doi: 10.3346/jkms.2014.29.3.378
The incretin effect, which is a unique stimulus of insulin secretion in response to oral ingestion of nutrients, is calculated by the difference in insulin secretory responses from an oral... -
- CITED
-
- Close
- SHARE
-
- Close
- Differential Effects of High-carbohydrate and High-fat Diet Composition on Muscle Insulin Resistance in Rats
-
Chun MR, Lee YJ, Kim KH, Kim YW, Park SY, Lee KM, Kim JY, Park YK
- KMID: 1792956
- J Korean Med Sci.
- 2010 Jul;25(7):1053-1059.
- doi: 10.3346/jkms.2010.25.7.1053
This study was conducted to evaluate whether the composition of carbohydrate or fat diet affects insulin resistance by measuring the muscle glucose transport rate. Both high-sucrose and high-starch diet with... -
- CITED
-
- Close
- SHARE
-
- Close
- Methylglyoxal Induces Apoptosis Mediated by Reactive Oxygen Species in Bovine Retinal Pericytes
-
Kim J, Son JW, Lee JA, Oh YS, Shinn SH
- KMID: 1785701
- J Korean Med Sci.
- 2004 Feb;19(1):95-100.
- doi: 10.3346/jkms.2004.19.1.95
One of the histopathologic hallmarks of early diabetic retinopathy is the loss of pericytes. Evidences suggest that the pericyte loss in vivo is mediated by apoptosis. However, the underlying cause... -
- CITED
-
- Close
- SHARE
-
- Close
- Associations among Body Mass Index, Insulin Resistance, and Pancreatic beta-Cell Function in Korean Patients with New-Onset Type 2 Diabetes
-
Chung JO, Cho DH, Chung DJ, Chung MY
- KMID: 1776568
- Korean J Intern Med.
- 2012 Mar;27(1):66-71.
- doi: 10.3904/kjim.2012.27.1.66
BACKGROUND/AIMS: We investigated the associations among body mass index (BMI), insulin resistance, and beta-cell function in Korean patients newly presenting with type 2 diabetes. METHODS: In total, 132 patients with new-onset... -
- CITED
-
- Close
- SHARE
-
- Close
- Repeated dose toxicity of alfa-cypermethrin in rats
-
Manna S, Bhattacharyya D, Mandal TK, Das S
- KMID: 1099838
- J Vet Sci.
- 2004 Sep;5(3):241-245.
The present study was performed to investigate the subacute effect of alpha-cypermethrin (alpha-CP) in rats. Alfacypermethrin a synthetic pyrethroid insecticide, dissolved in dimethyl sulfoxide (DMSO) and oral LD50 was investigated... -
- CITED
-
- Close
- SHARE
-
- Close
