- Forskolin Changes the Relationship between Cytosolic Ca2+ and Contraction in Guinea Pig Ileum
-
Han KH, Cheon GJ, Yeon DS, Kwon SC
- KMID: 2071670
- Korean J Physiol Pharmacol.
- 2009 Jun;13(3):189-194.
- doi: 10.4196/kjpp.2009.13.3.189
This study was designed to clarify the mechanism of the inhibitory effect of forskolin on contraction, cytosolic Ca2+ level ([Ca2+]i), and Ca2+ sensitivity in guinea pig ileum. Forskolin (0.1 nM~10... -
- CITED
-
- Close
- SHARE
-
- Close
- Forskolin Enhances Synaptic Transmission in Rat Dorsal Striatum through NMDA Receptors and PKA in Different Phases
-
Cho HS, Lee HH, Choi SJ, Kim KJ, Jeun SH, Li QZ, Sung KW
- KMID: 2285355
- Korean J Physiol Pharmacol.
- 2008 Dec;12(6):293-297.
- doi: 10.4196/kjpp.2008.12.6.293
The effect of forskolin on corticostriatal synaptic transmission was examined by recording excitatory postsynaptic currents (EPSCs) in rat brain slices using the whole-cell voltage-clamp technique. Forskolin produced a dose-dependent increase... -
- CITED
-
- Close
- SHARE
-
- Close
- Effects of propofol on beta-adrenoceptor-mediated signal transduction in cardiac muscle; role of cAMP
-
Chang CH, Roh GU, Park WK
- KMID: 2299336
- Korean J Anesthesiol.
- 2010 Apr;58(4):374-377.
- doi: 10.4097/kjae.2010.58.4.374
BACKGROUND: Propofol may decrease myocardial contractility via actions on the beta-adrenoceptor-mediated signal transduction. The aim of this study was to evaluate the effect of propofol via beta-adrenoceptor-mediated signal transduction by... -
- CITED
-
- Close
- SHARE
-
- Close
- PKC-Independent Stimulation of Cardiac Na+/Ca2+ Exchanger by Staurosporine
-
Kang TM
- KMID: 1486108
- Korean J Physiol Pharmacol.
- 2008 Oct;12(5):259-265.
- doi: 10.4196/kjpp.2008.12.5.259
[Ca2+]i transients by reverse mode of cardiac Na+/Ca2+ exchanger (NCX1) were recorded in fura-2 loaded BHK cells with stable expression of NCX1. Repeated stimulation of reverse NCX1 produced a long-lasting... -
- CITED
-
- Close
- SHARE
-
- Close
- Multi-facet expressions of adenylate cyclase isoforms in B16-F10 melanoma cells differentiated by forskolin treatment
-
Cho DH, Bae CD, Juhnn YS
- KMID: 755106
- Exp Mol Med.
- 2000 Dec;32(4):235-242.
The terminal differentiation of malignant melanoma cells is known to be induced by activating cAMP signaling pathway with alpha-MSH or cAMP analogues. However, sustained activation of cAMP signaling... -
- CITED
-
- Close
- SHARE
-
- Close
- Forskolin promotes astroglial differentiation of human central neurocytoma cells
-
Kim BJ, Kim SS, Kim YI, Paek SH, Lee YD, Suh-Kim H
- KMID: 755665
- Exp Mol Med.
- 2004 Feb;36(1):52-56.
Human central neurocytoma is a kind of the brain tumors that are usually found in anterior part of the lateral ventricles. In this study, we established conditions that allowed proliferation... -
- CITED
-
- Close
- SHARE
-
- Close
- Search for Materials that Influence Human Medullary Thyroid Carcinoma Cell Proliferation
-
Shin HW, Jang HW, Kim KS, Lee JI, Park JY, Kim SW, Min YK, Lee MS, Lee MK, Kim KW, Chung JH
- KMID: 1468503
- J Korean Endocr Soc.
- 2009 Jun;24(2):93-99.
- doi: 10.3803/jkes.2009.24.2.93
BACKGROUND: Surgical excision is the only effective treatment of medullary thyroid carcinoma (MTC) and there is no certain treatment for recurrence or distant metastasis. Materials that influence MTC cell proliferation... -
- CITED
-
- Close
- SHARE
-
- Close
- Stimulation of Cl- secretion by AlF4- and vanadate in T84 cells
-
Hwang TH, Jung JS, Bae HR, Yun I, Lee SH
- KMID: 644842
- J Korean Med Sci.
- 1994 Dec;9(6):497-504.
- doi: 10.3346/jkms.1994.9.6.497
We investigated the mechanism of Cl- secretion by fluoroaluminate(AlF4-) and sodium orthovanadate(vanadate) using the human colonic T84 cell line. T84 cell monolayers grown on collagen-coated filters were mounted in Ussing... -
- CITED
-
- Close
- SHARE
-
- Close
- Cholera toxin mediated regulation of the expression of Gq alpha and G11 alpha GTP binding proteins
-
Shah BH
- KMID: 1029937
- Exp Mol Med.
- 1999 Jun;31(2):89-94.
Previously it has been shown that persistent activation of the stimulatory adenylyl cyclase pathway with cholera toxin (CT) downregulates the Gs alpha polypeptide (80%) in a cAMP-independent manner in C6 glioma cells... -
- CITED
-
- Close
- SHARE
-
- Close
- Isolation of neural precursor cells from skeletal muscle tissues and their differentiation into neuron-like cells
-
Park JS, Kim S, Han DK, Lee JY, Ghil SH
- KMID: 756071
- Exp Mol Med.
- 2007 Aug;39(4):483-490.
Skeletal muscle contains several precursor cells that generate muscle, bone, cartilage and blood cells. Although there are reports that skeletal muscle-derived cells can trans-differentiate into neural-lineage cells, methods for isolating... -
- CITED
-
- Close
- SHARE
-
- Close
- Relaxation Patterns of Human Gastric Corporal Smooth Muscle by Cyclic Nucleotides Producing Agents
-
Kim YC, Choi W, Sung R, Kim H, You RY, Park SM, Youn SJ, Kim MJ, Song YJ, Xu WX, Lee SJ, Yun HY
- KMID: 2285388
- Korean J Physiol Pharmacol.
- 2009 Dec;13(6):503-510.
- doi: 10.4196/kjpp.2009.13.6.503
To elucidate the mechanism of cyclic nucleotides, such as adenosine 3',5'-cyclic monophosphate (cAMP) and guanosine 3',5' -cyclic monophosphate (cGMP), in the regulation of human gastric motility, we examined the effects... -
- CITED
-
- Close
- SHARE
-
- Close
- Comparison of Human Muscle-Derived Stem Cells and Human Adipose-Derived Stem Cells in Neurogenic Trans-Differentiation
-
Kwon EB, Lee JY, Piao S, Kim IG, Ra JC, Lee JY
- KMID: 2315549
- Korean J Urol.
- 2011 Dec;52(12):852-857.
PURPOSE: Erectile dysfunction (ED) remains a major complication from cavernous nerve injury during radical prostatectomy. Recently, stem cell treatment for ED has been widely reported. This study was conducted to... -
- CITED
-
- Close
- SHARE
-
- Close
- P2 Receptor-mediated Inhibition of Vasopressin-stimulated Fluid Transport and cAMP Responses in AQP2-transfected MDCK Cells
-
Kim YH, Choi YJ, Bae HR, Woo JS
- KMID: 2285365
- Korean J Physiol Pharmacol.
- 2009 Feb;13(1):9-14.
- doi: 10.4196/kjpp.2009.13.1.9
We cultured canine kidney (MDCK) cells stably expressing aquaporin-2 (AQP2) on collagen-coated permeable membrane filters and examined the effect of extracellular ATP on arginine vasopressin (AVP)-stimulated fluid transport and cAMP... -
- CITED
-
- Close
- SHARE
-
- Close
- Modulation of Presynaptic GABA Release by Oxidative Stress in Mechanically-isolated Rat Cerebral Cortical Neurons
-
Hahm ET, Seo JW, Hur J, Cho YW
- KMID: 2285392
- Korean J Physiol Pharmacol.
- 2010 Jun;14(3):127-132.
- doi: 10.4196/kjpp.2010.14.3.127
Reactive oxygen species (ROS), which include hydrogen peroxide (H2O2), the superoxide anion (O2-.), and the hydroxyl radical (OH.), are generated as by-products of oxidative metabolism in cells. The cerebral cortex... -
- CITED
-
- Close
- SHARE
-
- Close
- Neural Differentiation of Mesenchymal Stem Cells from Bone Marrow of Human Mastoid Process
-
Cho HH, Jeong HS, Jang SJ, Park JS, Cho HC, Jang CH, Cho YB
- KMID: 2074117
- Korean J Otorhinolaryngol-Head Neck Surg.
- 2008 May;51(5):422-428.
BACKGROUND AND OBJECTIVES: Reports of neural differentiation of mesenchymal stem cells suggest the possibility that these cells may serve as a source for stem cell-based regenerative medicine to treat neurological... -
- CITED
-
- Close
- SHARE
-
- Close
- A novel Na+-dependent transporter and NHE3 mediate H+ efflux in the luminal membrane of the pancreatic duct: regulation by cAMP
-
Lee MG, Ahn W, Choi JY, Muallem S, Kim KH
- KMID: 1026941
- J Korean Med Sci.
- 2000 Aug;15(Suppl):S29-S30.
- doi: 10.3346/jkms.2000.15.S.S29
No abstract available. -
- CITED
-
- Close
- SHARE
-
- Close
- Suppression of CFTR-mediated Cl- Secretion of Airway Epithelium in Vitamin C-deficient Mice
-
Kim Y, Kim H, Yoo HY, Kang JS, Kim SJ, Kim JK, Cho HS
- KMID: 2157866
- J Korean Med Sci.
- 2011 Mar;26(3):317-324.
- doi: 10.3346/jkms.2011.26.3.317
Hyperoxic ventilation induces detrimental effects on the respiratory system, and ambient oxygen may be harmful unless compensated by physiological anti-oxidants, such as vitamin C. Here we investigate the changes in... -
- CITED
-
- Close
- SHARE
-
- Close
- Effect of xanthohumol on melanogenesis in B16 melanoma cells
-
Koo JH, Kim HT, Yoon HY, Kwon KB, Choi IW, Jung SH, Kim HU, Park BH, Park JW
- KMID: 756333
- Exp Mol Med.
- 2008 Jun;40(3):313-319.
- doi: 10.3858/emm.2008.40.3.313
Xanthohumol (XH), the principal prenylflavonoid of the hop plant (Humulus lupulus L.), dose-dependently inhibited isobutylmethylxanthine (IBMX)-induced melanogenesis in B16 melanoma cells, with little cytotoxicity at the effective concentrations. Decreased melanin... -
- CITED
-
- Close
- SHARE
-
- Close
- Beta agonist regulation of sodium transport in fetal lung epithelium: roles of cell volume, cytosolic chloride and protein tyrosine kinase
-
Marunaka Y, Niisato N, Ito Y
- KMID: 1026947
- J Korean Med Sci.
- 2000 Aug;15(Suppl):S42-S43.
- doi: 10.3346/jkms.2000.15.S.S42
1) A beta agonist stimulated Na+ transport and decreased the intracellular Cl concentration ([Cl]c) associated with cell shrinkage via an increase in cytosolic cAMP level by activating adenylate cyclase in... -
- CITED
-
- Close
- SHARE
-
- Close
- Bee venom stimulates human melanocyte proliferation, melanogenesis, dendricity and migration
-
Jeon S, Kim NH, Koo BS, Lee HJ, Lee AY
- KMID: 1090963
- Exp Mol Med.
- 2007 Oct;39(5):603-613.
Pigmentation may result from melanocyte proliferation, melanogenesis, migration or increases in dendricity. Recently, it has been reported that secreted phospholipase A2(sPLA2) known as a component of bee venom (BV), stimulates... -
- CITED
-
- Close
- SHARE
-
- Close
