- Experience of a Single Center in Treating Multiple Manifestations of Tuberous Sclerosis Complex with Everolimus
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Ahn H, Yum MS, Jang HN, Song C, Ko TS
- KMID: 2470590
- Ann Child Neurol.
- 2019 Dec;27(4):135-145.
- doi: 10.26815/acn.2019.00206
PURPOSE: The aim of this study was to evaluate the efficacy and tolerability of everolimus, an oral mammalian target of rapamycin (mTOR) inhibitor, for the treatment of tuberous sclerosis complex... -
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- Cross-sectional analysis of immunosuppressive regimens focused on everolimus after liver transplantation in a Korean high-volume transplantation center
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Kang SH, Hwang S, Ha TY, Song GW, Jung DH, Ahn CS, Moon DB, Kim KH, Park GC, Yoon YI, Park YH, Cho HD, Kwon JH, Chung YK, Choi JU, Lee SG
- KMID: 2468159
- Korean J Transplant.
- 2019 Dec;33(4):98-105.
- doi: 10.4285/jkstn.2019.33.4.98
BACKGROUND: The mammalian target of the rapamycin inhibitor has dual inhibitory effects on cell growth and angiogenesis. This study aimed to analyze the usage of everolimus on actual immunosuppression (IS)... -
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- The Systematic Review of the Efficacy and Safety of Immune Checkpoint Inhibitor in Urological Cancers
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Hwang GY, Choi SY, Chang IH
- KMID: 2457590
- Korean J Urol Oncol.
- 2019 Aug;17(2):75-80.
- doi: 10.22465/kjuo.2019.17.2.75
To systematically review relevant literature on efficacy and safety of immune checkpoint inhibitors (ICIs) in patients with advanced and metastatic urothelial cell cancer (UCC), renal cell cancer (RCC), and prostate... -
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- Tuberous Sclerosis Complex with Crohn's Disease
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Kim MH, Lee YJ, Kim JY, Yi YY, Kang JW
- KMID: 2437115
- J Korean Child Neurol Soc.
- 2018 Dec;26(4):284-287.
- doi: 10.26815/jkcns.2018.26.4.284
Tuberous sclerosis complex (TSC) is an autosomal dominant disorder caused by mutation of one of two genes, TSC1 (encoding hamartin, 9q34) and TSC2 (encoding tuberin, 16p13). It invades the central... -
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- Everolimus Plus Ku0063794 Regimen Promotes Anticancer Effects against Hepatocellular Carcinoma Cells through the Paradoxical Inhibition of Autophagy
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Lee SC, Kim KH, Kim OH, Lee SK, Hong HE, Choi BJ, Jeong W, Kim SJ
- KMID: 2417890
- Cancer Res Treat.
- 2018 Jul;50(3):1023-1038.
- doi: 10.4143/crt.2017.085
PURPOSE: Everolimus only inhibits mammalian target of rapamycin complex 1 (mTORC1), whereas Ku0063794 inhibits both mTORC1 and mTORC2. Although they have similar anticancer effects, their combination has a synergistic effect... -
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- Management of very late peritoneal metastasis of hepatocellular carcinoma 10 years after liver transplantation: Lessons from two cases
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Alshahrani AA, Hwang S, Song GW, Moon DB, Jung DH, Ahn CS, Kim KH, Ha TY, Park GC, Ha SM, Park YH, Lee SG
- KMID: 2412428
- Ann Hepatobiliary Pancreat Surg.
- 2018 May;22(2):136-143.
- doi: 10.14701/ahbps.2018.22.2.136
Recurrence of hepatocellular carcinoma (HCC) 10 years after liver transplantation (LT) is very rare. Here, we present two cases of peritoneal metastasis of HCC that occurred 10 and 12 years... -
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- Impact of â¶â¸Ga-DOTA-Peptide PET/CT on the Management of Gastrointestinal Neuroendocrine Tumour (GI-NET): Malaysian National Referral Centre Experience
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Tan TH, Boey CY, Lee BN
- KMID: 2414799
- Nucl Med Mol Imaging.
- 2018 Apr;52(2):119-124.
- doi: 10.1007/s13139-017-0496-3
PURPOSE: The National Cancer Institute is the only referral centre in Malaysia that provides â¶â¸Ga-DOTA-peptide imaging. The purpose of this study is to determine the impact of â¶â¸Ga-DOTA-peptide PET/CT on... -
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- Fibrous Plaque of the Eyelid in a Patient with Tuberous Sclerosis Responding to Everolimus
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Park SM, Kim BS, Kim MB, Lee YJ, Ko HC
- KMID: 2414696
- Ann Dermatol.
- 2018 Apr;30(2):247-249.
- doi: 10.5021/ad.2018.30.2.247
No abstract available. -
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- Crizotinib in Combination with Everolimus Synergistically Inhibits Proliferation of Anaplastic Lymphoma Kinase‒Positive Anaplastic Large Cell Lymphoma
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Xu W, Kim JW, Jung WJ, Koh Y, Yoon SS
- KMID: 2411148
- Cancer Res Treat.
- 2018 Apr;50(2):599-613.
- doi: 10.4143/crt.2016.357
PURPOSE: Anaplastic large cell lymphoma (ALCL) is a rare aggresive non-Hodgkin lymphoma, of which over 50% of cases have an aberrant nucleophosmin (NPM)‒anaplastic lymphoma kinase (ALK) fusion protein. Both mechanistic... -
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- Living donor liver transplantation prior to multiple myeloma treatment in a patient with hepatitis B-associated hepatocellular carcinoma and liver cirrhosis: a case report
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Cho CW, Lee N, Choi GS, Kim JM, Kwon CH, Joh JW
- KMID: 2407752
- Ann Surg Treat Res.
- 2018 Apr;94(4):216-218.
- doi: 10.4174/astr.2018.94.4.216
Clinical outcomes of living donor liver transplantation (LDLT) for hepatocellular carcinoma (HCC) in patients with multiple myeloma (MM) have not been established in terms of HCC recurrence and MM deterioration... -
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- A cross-sectional analysis of long-term immunosuppressive regimens after liver transplantation at Asan Medical Center: Increased preference for mycophenolate mofetil
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Hwang S, Ahn CS, Kim KH, Moon DB, Ha TY, Song GW, Jung DH, Park GC, Lee SG
- KMID: 2409076
- Ann Hepatobiliary Pancreat Surg.
- 2018 Feb;22(1):19-26.
- doi: 10.14701/ahbps.2018.22.1.19
BACKGROUNDS/AIMS: Long-term immunosuppression regimens after liver transplantation (LT) are rarely reported in detail. We aimed to provide information on actual long-term immunosuppression regimens through this cross-sectional study. METHODS: Our institutional LT... -
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- Biomarkers of Everolimus Sensitivity in Hormone Receptor-Positive Breast Cancer
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Yi Z, Ma F
- KMID: 2398200
- J Breast Cancer.
- 2017 Dec;20(4):321-326.
- doi: 10.4048/jbc.2017.20.4.321
Activation of the mammalian target of rapamycin (mTOR) signaling pathway is an important mechanism of resistance to endocrine therapy in breast cancer. Everolimus, an mTOR inhibitor, has been shown to... -
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- Assessing the role of everolimus in reducing hepatocellular carcinoma recurrence after living donor liver transplantation for patients within the UCSF criteria: re-inventing the role of mammalian target of rapamycin inhibitors
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Thorat A, Jeng LB, Yang HR, Yeh CC, Hsu SC, Chen TH, Poon KS
- KMID: 2397800
- Ann Hepatobiliary Pancreat Surg.
- 2017 Nov;21(4):205-211.
- doi: 10.14701/ahbps.2017.21.4.205
BACKGROUNDS/AIMS: The protective effect of everolimus (EVR) in hepatocellular carcinoma (HCC) patients who receive liver transplantation in terms of reducing the recurrence has not been sufficiently investigated in clinical trials.... -
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- Everolimus-induced activation of latent Mycobacterium tuberculosis infection in a patient with metastatic renal cell carcinoma
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Jeon SY, Yhim HY, Lee NR, Song EK, Kwak JY, Yim CY
- KMID: 2371662
- Korean J Intern Med.
- 2017 Mar;32(2):365-368.
- doi: 10.3904/kjim.2015.121
No abstract available. -
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- Heart Retransplantation to Treat a Case of Refractory Cardiac Allograft Vasculopathy
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Lee SY, Choi JO, Kim YJ, Choi JS, Lee GY, Kim JS, Jeon ES
- KMID: 2361435
- Korean J Med.
- 2016 Dec;91(3):287-291.
- doi: 10.3904/kjm.2016.91.3.287
Cardiac allograft vasculopathy is one of the most important causes of poor long-term survival after heart transplantation. The condition tends to be diffuse, usually affecting the mid-to-distal portions of the... -
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- Efficacy and Toxicity of Mammalian Target Rapamycin Inhibitors in Patients with Metastatic Renal Cell Carcinoma with Renal Insufficiency: The Korean Cancer Study Group GU 14-08
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Kim KH, Kim JH, Lee JY, Kim HS, Heo SJ, Kim JH, Kim HY, Rha SY
- KMID: 2356230
- Cancer Res Treat.
- 2016 Oct;48(4):1286-1292.
- doi: 10.4143/crt.2016.018
PURPOSE: We evaluated the efficacy and toxicity of mammalian target rapamycin inhibitors in Korean patients with metastatic renal cell carcinoma (mRCC) with chronic renal insufficiency not requiring dialysis. MATERIALS AND METHODS:... -
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- Optimal Treatment of Advanced Pancreatic Neuroendocrine Tumor
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Kim YS, Cho JH
- KMID: 2448526
- Korean J Pancreas Biliary Tract.
- 2016 Jul;21(3):128-137.
- doi: 10.15279/kpba.2016.21.3.128
Pancreatic neuroendocrine tumors (pNETs) are diverse diseases with different prognosis. Among available various therapeutic options, curative resection should be considered for localized tumors and in some selected cases of metastatic... -
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- Chemotherapy and Targeted Therapy beyond Adenocarcinoma of the Lung: Neuroendocrine Carcinoma
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Kwon JH
- KMID: 2268883
- Korean J Med.
- 2016 Jan;90(1):7-14.
- doi: 10.3904/kjm.2016.90.1.7
Neuroendocrine carcinoma (NEC) has been reported to comprise 25% of lung cancer cases. NEC is classified as typical carcinoid, atypical carcinoid, large-cell neuroendocrine carcinoma, and small-cell lung cancer. Carcinoid tumors... -
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- A Case of Primary Lung Cancer Mistaken for Pulmonary Metastasis of Renal Cell Carcinoma
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Kim JD, Kwon YJ, Lee ES, Kim YS, Lee YJ, Kong SM, Ji JH
- KMID: 2268961
- Korean J Med.
- 2015 Nov;89(5):576-580.
- doi: 10.3904/kjm.2015.89.5.576
Renal cell carcinoma (RCC) is rare relative to other urological cancers, but relatively common overall among males. Even when primary tumors are successfully removed by surgery, metastases are often noted... -
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- Efficacy and Safety of Everolimus in Korean Patients with Metastatic Renal Cell Carcinoma Following Treatment Failure with a Vascular Endothelial Growth Factor Receptor-Tyrosine Kinase Inhibitor
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Park K, Lee JL, Ahn JH, Lee KH, Jeong IG, Song C, Hong B, Hong JH, Ahn H
- KMID: 2380371
- Cancer Res Treat.
- 2014 Oct;46(4):339-347.
- doi: 10.4143/crt.2013.154
PURPOSE: The purpose of this study is to assess the efficacy and safety of everolimus in Korean patients with metastatic renal cell carcinoma (mRCC) for whom initial treatment with a... -
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