- Phosphorylation of Akt Mediates Anti-Inflammatory Activity of 1-p-Coumaroyl beta-D-Glucoside Against Lipopolysaccharide-Induced Inflammation in RAW264.7 Cells
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Vo VA, Lee JW, Kim JY, Park JH, Lee HJ, Kim SS, Kwon YS, Chun W
- KMID: 2285495
- Korean J Physiol Pharmacol.
- 2014 Feb;18(1):79-86.
- doi: 10.4196/kjpp.2014.18.1.79
Hydroxycinnamic acids have been reported to possess numerous pharmacological activities such as antioxidant, anti-inflammatory, and anti-tumor properties. However, the biological activity of 1-p-coumaroyl beta-D-glucoside (CG), a glucose ester derivative of... -
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- Effects of Sinapic Acid of 4 Vessel Occlusion Model-Induced Ischemia and Cognitive Impairments in the Rat
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Kim YO, Lee SW, Oh MS, Lee HJ
- KMID: 2171265
- Clin Psychopharmacol Neurosci.
- 2011 Aug;9(2):86-90.
OBJECTIVE: Sinapic acid (SA, Sinapine), small naturally occurring hydroxycinnamic acid, has a GABA(A) receptor agonistic property and free radical scavenging activity. We examined potential neuroprotective effects of sinapic acid (SA)... -
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- Ferulic acid modulates nitric oxide synthase expression in focal cerebral ischemia
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Koh PO
- KMID: 1431411
- Lab Anim Res.
- 2012 Dec;28(4):273-278.
- doi: 10.5625/lar.2012.28.4.273
Nitric oxide (NO) is generated by three different NO synthase (NOS) isoforms, endothelial NOS (eNOS), inducible NOS (iNOS), and neuronal NOS (nNOS). It is known that eNOS produces NO, which... -
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- 3,4,5-Trihydroxycinnamic Acid Inhibits LPS-Induced iNOS Expression by Suppressing NF-kappaB Activation in BV2 Microglial Cells
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Lee JW, Bae CJ, Choi YJ, Kim SI, Kim NH, Lee HJ, Kim SS, Kwon YS, Chun W
- KMID: 2071755
- Korean J Physiol Pharmacol.
- 2012 Apr;16(2):107-112.
- doi: 10.4196/kjpp.2012.16.2.107
Although various derivatives of caffeic acid have been reported to possess a wide variety of biological activities such as neuronal protection against excitotoxicity and anti-inflammatory property, the biological activity of... -
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- 3,4,5-Trihydroxycinnamic Acid Inhibits Lipopolysaccharide-Induced Inflammatory Response through the Activation of Nrf2 Pathway in BV2 Microglial Cells
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Lee JW, Choi YJ, Park JH, Sim JY, Kwon YS, Lee HJ, Kim SS, Chun W
- KMID: 2170687
- Biomol Ther.
- 2013 Jan;21(1):60-65.
3,4,5-Trihydroxycinnamic acid (THC) is a derivative of hydroxycinnamic acids, which have been reported to possess a variety of biological properties such as anti-inflammatory, anti-tumor, and neuroprotective activities. However, biological activity... -
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- Ferulic acid regulates the AKT/GSK-3beta/CRMP-2 signaling pathway in a middle cerebral artery occlusion animal model
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Gim SA, Sung JH, Shah FA, Kim MO, Koh PO
- KMID: 1431333
- Lab Anim Res.
- 2013 Jun;29(2):63-69.
- doi: 10.5625/lar.2013.29.2.63
Ferulic acid, a component of the plants Angelica sinensis (Oliv.) Diels and Ligusticum chuanxiong Hort, exerts a neuroprotective effect by regulating various signaling pathways. This study showed that ferulic acid... -
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- Endothelium-dependent vasodilation by ferulic acid in aorta from chronic renal hypertensive rats
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Choi S, Kim HI, Park SH, Lee MJ, Jun JY, Kim HL, Chung JH, Yeum CH
- KMID: 1426333
- Kidney Res Clin Pract.
- 2012 Dec;31(4):227-233.
BACKGROUND: Ferulic acid (FA) is a naturally occurring nutritional compound. Although it has been shown to have antihypertensive effects, its effects on vascular function have not been intensively established. The... -
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- Assessment of Antioxidant and Phenolic Compound Concentrations as well as Xanthine Oxidase and Tyrosinase Inhibitory Properties of Different Extracts of Pleurotus citrinopileatus Fruiting Bodies
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Alam N, Yoon KN, Lee KR, Kim HY, Shin PG, Cheong JC, Yoo YB, Shim MJ, Lee MW, Lee TS
- KMID: 2312605
- Mycobiology.
- 2011 Mar;39(1):12-19.
Cellular damage caused by reactive oxygen species has been implicated in several diseases, thus establishing a significant role for antioxidants in maintaining human health. Acetone, methanol, and hot water extracts... -
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- Study on the hypochlolesterolemic and antioxidative effects of tyramine derivatives from the root bark of Lycium chenese Miller
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Cho SH, Park EJ, Kim EO, Choi SW
- KMID: 2313546
- Nutr Res Pract.
- 2011 Oct;5(5):412-420.
The aim of the present study was to investigate the hypocholesterolemic effect and potential of tyramine derivatives from Lycii Cortex Radicis (LCR), the root bark of lycium (Lycium chenese Miller)... -
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- Effects of ferulic acid on diabetic nephropathy in a rat model of type 2 diabetes
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Choi R, Kim BH, Naowaboot , Lee MY, Hyun MR, Cho EJ, Lee ES, Lee EY, Yang YC, Chung CH
- KMID: 1058705
- Exp Mol Med.
- 2011 Dec;43(12):676-683.
- doi: 10.3858/emm.2011.43.12.078
Diabetic nephropathy is the most serious complication in diabetes mellitus. It is known that oxidative stress and inflammation play a central role in the development of diabetic nephropathy. In this... -
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