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Seasonal influenza and vaccine herd effect

Kim TH

The seasonal influenza vaccine programs in many regions aimed to protect most vulnerable population, but current trivalent influenza vaccine does not provide sufficient effectiveness among people under high risk for...
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Dendritic cell-based therapeutic cancer vaccines: past, present and future

Ahmed MS, Bae YS

No abstract available.
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Host immune responses to mycobacterial antigens and their implications for the development of a vaccine to control tuberculosis

Yuk JM, Jo EK

Tuberculosis (TB) remains a worldwide health problem, causing around 2 million deaths per year. Despite the bacillus Calmette Guerin vaccine being available for more than 80 years, it has limited...
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Current status of human papillomavirus vaccines

Kim KS, Park SA, Ko KN, Yi S, Cho YJ

Cervical cancer is a malignant neoplasm arising from cells that originate in the cervix uteri. It is the second most prevalent cancer among women. It can have several causes; an...
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Progress and hurdles in the development of influenza virus-like particle vaccines for veterinary use

Lee DH, Park JK, Song CS

Virus-like particles (VLPs), which resemble infectious virus particles in structure and morphology, have been proposed to provide a new generation of vaccine candidates against various viral infections. As effective immunogens,...
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Evolutionary dynamics of highly pathogenic avian influenza A/H5N1 HA clades and vaccine implementation in Vietnam

Le TH, Nguyen NT

Based on hemagglutinin (HA) and neuraminidase (NA), influenza A virus is divided into 18 different HA (H1 to H18) and 11 NA types (N1 to N11), opening the possibility for...
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Assessment of mOMV adjuvant efficacy in the pathogenic H1N1 influenza virus vaccine

Lee BJ, Kwon HI, Kim EH, Park SJ, Lee SH, Choi YK, Kim SH

PURPOSE: Since the pandemic (H1N1) 2009 virus has been a seasonal flu which still poses great human health concerns worldwide, vaccination would be considered as the most effective strategy to...
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Vaccine strategies utilizing C-type lectin receptors on dendritic cells in vivo

Park CG

Dendritic cells (DCs) are professional antigen-presenting cells capable of initiating and regulating innate and adaptive immunity. The development of effective ways to produce a large number of DCs in laboratories...
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Inactivated genotype 1 Japanese encephalitis vaccine for swine

Yang DK, Nah JJ, Kim HH, Song JY

PURPOSE: Japanese encephalitis is a reproductive disorder caused by Japanese encephalitis virus (JEV) in swine. Recent genotype (G) shift phenomenon (G3 to G1) in the Asia-wide has posed a challenge...
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Guidelines for vaccination of dogs and cats in Korea

Song WJ, Kim HT, Yoo HS, Youn HY

This guideline contains the recommended vaccination schedules of dogs and cats from World Small Animal Veterinary Association (WSAVA) and American Animal Hospital Association (AAHA). In 2010, WSAVA published guidelines for...
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Lumazine synthase protein cage nanoparticles as antigen delivery nanoplatforms for dendritic cell-based vaccine development

Ra JS, Shin HH, Kang S, Do Y

PURPOSE: Protein cages are promising nanoplatform candidates for efficient delivery systems due to their homogenous size and structure with high biocompatibility and biodegradability. In this study, we investigate the potential...
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Zoonotic infections with avian influenza A viruses and vaccine preparedness: a game of "mix and match"

Pascua PN, Choi YK

Various direct avian-to-human transmissions of influenza A virus subtypes upon exposure to infected poultry have been previously observed in the past decades. Although some of these strains caused lethal infections,...
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Immunogenicity and efficacy of a plasmid DNA rabies vaccine incorporating Myd88 as a genetic adjuvant

Ullas PT, Desai A, Madhusudana SN

PURPOSE: Myeloid differentiation factor 88 (Myd88), a ubiquitous Toll-like receptor adaptor molecule, has been reported to play important roles in B cell responses to infections and vaccination. The present study...
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First trials of oral vaccination with rabies SAG2 dog baits in Morocco

Darkaoui S, Boue F, Demerson J, Fassi Fihri O, Yahia KI, Cliquet F

PURPOSE: Canine rabies is a serious health problem in Morocco and about 22 human deaths are reported yearly. Following the World Health Organization (WHO) recommendations, Moroccan authorities evaluated oral rabies...
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A single immunization with recombinant rabies virus (ERAG3G) confers complete protection against rabies in mice

Yang DK, Nakagawa K, Ito N, Kim HH, Hyun BH, Nah JJ, Sugiyama M, Song JY

PURPOSE: New alternative bait rabies vaccines applicable to pet dogs and wild animals are needed to eradicate rabies in Korea. In this study, recombinant rabies virus, ERAG3G strain was constructed...
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DNA immunization of Mycobacterium tuberculosis resuscitation-promoting factor B elicits polyfunctional CD8+ T cell responses

Lee J, Kim J, Lee J, Shin SJ, Shin EC

PURPOSE: T cell-mediated immune responses, and particularly activation of polyfunctional T cells that simultaneously produce multiple cytokines, are necessary for the control of Mycobacterium tuberculosis. In the present study, we...
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Cellular immunity survey against urinary tract infection using pVAX/fimH cassette with mammalian and wild type codon usage as a DNA vaccine

Imani Fooladi AA, Bagherpour G, Khoramabadi N, Fallah Mehrabadi J, Mahdavi M, Halabian R, Amin M, Izadi Mobarakeh J, Einollahi

PURPOSE: FimH (the adhesion fragment of type 1 fimbriae) is implicated in uropathogenic Escherichia coli (UPEC) attachment to epithelial cells through interaction with mannose. Recently, some studies have found that...
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