- The Spermatogenic Effect of Yacon Extract and Its Constituents and Their Inhibition Effect of Testosterone Metabolism
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Park JS, Han K
- KMID: 1502518
- Biomol Ther.
- 2013 Mar;21(2):153-160.
We screened the pharmacological effects of a 50% ethanol extract of Yacon tubers and leaves on spermatogenesis in rats. As a result, we found that Yacon tuber extracts increased sperm... -
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- The Anti-angiogenic Effect of Chlorogenic Acid on Choroidal Neovascularization
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Kim C, Yu HG, Sohn J
- KMID: 945987
- Korean J Ophthalmol.
- 2010 Jun;24(3):163-168.
- doi: 10.3341/kjo.2010.24.3.163
PURPOSE: To evaluate the inhibitory effect of chlorogenic acid on laser-induced choroidal neovascularization (CNV) in a rat model. METHODS: Intraperitoneal injection of chlorogenic acid (10 mg/kg) was inititated one day... -
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- Chlorogenic Acid Supplementation Improves Multifocal Electroretinography in Patients with Retinitis Pigmentosa
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Shin JY, Yu HG
- KMID: 1796924
- J Korean Med Sci.
- 2014 Jan;29(1):117-121.
- doi: 10.3346/jkms.2014.29.1.117
To evaluate the effect of chlorogenic acid supplementation in patients with retinitis pigmentosa, we evaluated objective change in visual function with multifocal electroretinography, along with visual acuity, visual field, standard... -
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- Simultaneous Determination of Four Compounds from Artemisia capillaris using High Performance Liquid Chromatography-Ultraviolet Detector (HPLC-UVD) and Their Quantitative Study in Artemisia Genus
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Ko K, Hong IK, Cho HJ, Kim YH, Yang H
- KMID: 2416071
- Nat Prod Sci.
- 2018 Jun;24(2):109-114.
- doi: 10.20307/nps.2018.24.2.109
Artemisia capillaris Thunb. (Compositae) is a native herb of East Asian countries and has used for the treatment of jaundice, high liver fever, and digestive diseases for a long time,... -
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- Protective Effects of Chlorogenic Acid against Experimental Reflux Esophagitis in Rats
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Kang JW, Lee SM
- KMID: 2380319
- Biomol Ther.
- 2014 Sep;22(5):420-425.
- doi: 10.4062/biomolther.2014.066
Esophageal reflux of gastric contents causes esophageal mucosal damage and inflammation. Recent studies show that oxygen-derived free radicals mediate mucosal damage in reflux esophagitis (RE). Chlorogenic acid (CGA), an ester... -
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- Chlorogenic Acid Decreases Retinal Vascular Hyperpermeability in Diabetic Rat Model
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Shin JY, Sohn J, Park KH
- KMID: 1786971
- J Korean Med Sci.
- 2013 Apr;28(4):608-613.
- doi: 10.3346/jkms.2013.28.4.608
To evaluate the effect of chlorogenic acid (CGA), a polyphenol abundant in coffee, on retinal vascular leakage in the rat model of diabetic retinopathy, Sprague-Dawley rats were divided into four... -
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- Phytochemical Analysis of the Phenolic Fat-Suppressing Substances in the Leaves of Lactuca raddeana in 3T3-L1 Adipocytes
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Nugroho A, Choi JS, An HJ, Park HJ
- KMID: 2409598
- Nat Prod Sci.
- 2015 Mar;21(1):42-48.
- doi: 10.0000/nps.2015.21.1.42
Lactuca raddeana (Compositae) is used to treat obesity and complications due to diabetes. The five phenolic compounds including chlorogenic acid, chicoric acid, luteolin 7-O-glucoside, luteolin 7-O-glucuronide, luteolin were qualitatively identified... -
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- The Polyphenol Chlorogenic Acid Attenuates UVB-mediated Oxidative Stress in Human HaCaT Keratinocytes
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Cha JW, Piao MJ, Kim KC, Yao CW, Zheng J, Kim SM, Hyun CL, Ahn YS, Hyun JW
- KMID: 2170653
- Biomol Ther.
- 2014 Mar;22(2):136-142.
We investigated the protective effects of chlorogenic acid (CGA), a polyphenol compound, on oxidative damage induced by UVB exposure on human HaCaT cells. In a cell-free system, CGA scavenged 1,1-diphenyl-2-picrylhydrazyl... -
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- Chlorogenic Acid Improves Neuroprotective Effect of PEP-1-Ribosomal Protein S3 Against Ischemic Insult
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Ahn EH, Kim DW, Shin MJ, Kwon SW, Kim YN, Kim DS, Lim SS, Kim J, Park J, Eum WS, Hwang HS, Choi SY
- KMID: 1495346
- Exp Neurobiol.
- 2011 Dec;20(4):169-175.
- doi: 10.5607/en.2011.20.4.169
Chlorogenic acid (CGA) possesses various biological activities such as anti-oxidant, anti-inflammatory, and anti-diabetic activities. In the present study, we examined the effect of CGA on the transduction efficiency of PEP-1-ribosomal... -
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- Quantitative Determination of Five Phenolic Peroxynitrite-scavengers in Nine Korean Native Compositae herbs
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Nugroho A, Lim SC, Karki S, Choi JS, Park HJ
- KMID: 2312890
- Nat Prod Sci.
- 2015 Sep;21(3):155-161.
- doi: 10.0000/nps.2015.21.3.155
Peroxynitrite (ONOO-)-scavenging activities of nine Compositae herbs consisting of three Ixeris, two Youngia, two Cirsium and one of each Lactuca and Taraxacum species were evaluated. The contents of their ONOO-... -
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- Development and Validation of HPLC-PDA Method and Pattern Recognition Analyses Using Eight Marker Compounds for the Quality Control Between the Seeds of Cuscuta chinensis Lam. and Cuscuta japonica Choisy
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Nguyen DH, Zhao BT, Le DD, Ma ES, Min BS, Woo MH
- KMID: 2468067
- Nat Prod Sci.
- 2019 Dec;25(4):334-340.
- doi: 10.20307/nps.2019.25.4.334
Cuscuta chinensis Lam. and Cuscuta japonica Choisy are parasitic plants. C. chinensis seeds were traditionally used for treatment of kidney and liver deficiencies. C. japonica seeds were used as tonic... -
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- Coffee and metabolic syndrome: A systematic review and meta-analysis
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Lee Y, Son J, Jang J, Park K
- KMID: 2351349
- J Nutr Health.
- 2016 Aug;49(4):213-222.
- doi: 10.4163/jnh.2016.49.4.213
PURPOSE: Coffee is the most frequently consumed food item in South Korea after rice and cabbage. Coffee contains various substances, including caffeine, cafestol, kahweol, chlorogenic acid, and many other known... -
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- Antioxidant Activities and Tyrosinase Inhibitory Effects of Different Extracts from Pleurotus ostreatus Fruiting Bodies
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Alam N, Yoon KN, Lee KR, Shin PG, Cheong JC, Yoo YB, Shim JM, Lee MW, Lee UY, Lee TS
- KMID: 2312593
- Mycobiology.
- 2010 Dec;38(4):295-301.
We evaluated the antioxidant activity and tyrosinase inhibitory effects of Pleurotus ostreatus fruiting bodies extracted with acetone, methanol, and hot water. The antioxidant activities were tested against beta-carotene-linoleic acid, reducing... -
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- The Cytotoxicity of Kahweol in HT-29 Human Colorectal Cancer Cells Is Mediated by Apoptosis and Suppression of Heat Shock Protein 70 Expression
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Choi DW, Lim MS, Lee JW, Chun W, Lee SH, Nam YH, Park JM, Choi DH, Kang CD, Lee SJ, Park SC
- KMID: 2380345
- Biomol Ther.
- 2015 Mar;23(2):128-133.
- doi: 10.4062/biomolther.2014.133
Although coffee is known to have antioxidant, anti-inflammatory, and antitumor properties, there have been few reports about the effect and mechanism of coffee compounds in colorectal cancer. Heat shock proteins... -
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- Assessment of Antioxidant and Phenolic Compound Concentrations as well as Xanthine Oxidase and Tyrosinase Inhibitory Properties of Different Extracts of Pleurotus citrinopileatus Fruiting Bodies
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Alam N, Yoon KN, Lee KR, Kim HY, Shin PG, Cheong JC, Yoo YB, Shim MJ, Lee MW, Lee TS
- KMID: 2312605
- Mycobiology.
- 2011 Mar;39(1):12-19.
Cellular damage caused by reactive oxygen species has been implicated in several diseases, thus establishing a significant role for antioxidants in maintaining human health. Acetone, methanol, and hot water extracts... -
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