- Prediction of Cancer Incidence and Mortality in Korea, 2020
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Jung KW, Won YJ, Hong S, Kong HJ, Lee ES
- KMID: 2500320
- Cancer Res Treat.
- 2020 Apr;52(2):351-358.
- doi: 10.4143/crt.2020.203
Purpose This study aimed to report the projected cancer incidence and mortality for the year 2020 to estimate Korea’s current cancer burden. Materials and Methods Cancer incidence data from 1999 to 2017 were obtained... -
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- Outcomes of Pregnancy after Breast Cancer in Korean Women:A Large Cohort Study
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Lee MH, Kim YA, Hong JH, Jung SY, Lee S, Kong SY, Park B, Lee ES
- KMID: 2500328
- Cancer Res Treat.
- 2020 Apr;52(2):426-437.
- doi: 10.4143/crt.2018.382
Purpose The purpose of this study was to determine the rate and outcomes of pregnancies subsequent to breast cancer in Korea, and the effect of such pregnancies on the prognosis of women who... -
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- Cancer Statistics in Korea: Incidence, Mortality, Survival, andPrevalence in 2017
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Hong S, Won YJ, Park YR, Jung KW, Kong HJ, Lee ES, The Community of Population-Based, Regional Cancer Registries
- KMID: 2500319
- Cancer Res Treat.
- 2020 Apr;52(2):335-350.
- doi: 10.4143/crt.2020.206
Purpose This study reports the cancer statistics and temporal trends in Korea on a nationwide scale, including incidence, survival, prevalence, and mortality in 2017. Materials and Methods The incidence, survival, and prevalence rates of... -
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- Impact of Prior Cancer History on the Clinical Outcomes in AdvancedBreast Cancer: A Propensity Score–Adjusted, Population-Based Study
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Lin C, Wu J, Ding S, Goh C, Andriani L, Shen K, Zhu L
- KMID: 2500340
- Cancer Res Treat.
- 2020 Apr;52(2):552-562.
- doi: 10.4143/crt.2019.210
Purpose Despite the rapid growing of cancer survivors, prior cancer history is a commonly adopted exclusion criterion. Whether prior cancer will impact the survival of patients with advanced breast cancer (ABC) remains uncertain. Materials... -
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- Changes of End of Life Practices for Cancer Patients and TheirAssociation with Hospice Palliative Care Referral over 2009-2014:A Single Institution Study
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Jho HJ, Nam EJ, Shin IW, Kim SY
- KMID: 2500327
- Cancer Res Treat.
- 2020 Apr;52(2):419-425.
- doi: 10.4143/crt.2018.648
Purpose In Korea, hospice palliative care (HPC) provision for cancer patients has increased recently. However, whether end of life (EoL) care practices have improved along with the development of HPC is unclear. We... -
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- A Modified NHL-BFM-95 Regimen Produces Better Outcome ThanHyperCVAD in Adult Patients with T-Lymphoblastic Lymphoma,a Two-Institution Experience
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Li C, Wuxiao ZJ, Chen X, Chen G, Lu Y, Xia Z, Liang Y, Wang H
- KMID: 2500342
- Cancer Res Treat.
- 2020 Apr;52(2):573-585.
- doi: 10.4143/crt.2019.542
Purpose Lymphoblastic lymphoma (LBL) is an invasive neoplasm of precursor T-cell or B-cell lineage. A broadly accepted standard treatment for adult LBL has not yet been defined. Materials and Methods To address this issue,... -
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- CXCL-13 Regulates Resistance to 5-Fluorouracil in Colorectal Cancer
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Zhang G, Luo X, Zhang W, Chen E, Xu J, Wang F, Cao G, Ju Z, Jin D, Huang X, Zhou W, Song Z
- KMID: 2500346
- Cancer Res Treat.
- 2020 Apr;52(2):622-633.
- doi: 10.4143/crt.2019.593
Purpose 5-Fluorouracil (5-Fu) is used as a conventional chemotherapy drug in chemotherapy for patients with advanced colorectal cancer, but many patients still suffer from treatment failure due to 5-Fu resistance. Emerging observations revealed... -
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- Body Mass Index and Risk of Gastric Cancer in Asian Adults:A Meta-Epidemiological Meta-Analysis of Population-BasedCohort Studies
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Bae JM
- KMID: 2500322
- Cancer Res Treat.
- 2020 Apr;52(2):369-373.
- doi: 10.4143/crt.2019.241
Purpose A previous meta-analysis (MA) published in 2009 reported that excess body weight was associated with an increased risk of gastric cancer in non-Asians, but not in Asians. The aim was to conduct... -
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- Prevalence and Clinicopathological Significance of METOverexpression and Gene Amplification in Patients withGallbladder Carcinoma
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Kim Y, Bang SS, Jee S, Park S, Shin SJ, Jang K
- KMID: 2500333
- Cancer Res Treat.
- 2020 Apr;52(2):481-491.
- doi: 10.4143/crt.2019.370
Purpose Mesenchymal epithelial transition (MET) is a proto-oncogene that encodes a heterodimeric transmembrane receptor tyrosine kinase for the hepatocyte growth factor. Aberrant MET signaling has been described in several solid tumors—especially non-small cell... -
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- Type-Specific Viral Load and Physical State of HPV Type 16, 18,and 58 as Diagnostic Biomarkers for High-Grade SquamousIntraepithelial Lesions or Cervical Cancer
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Kim J, Kim BK, Jeon D, Lee CH, Roh JW, Kim JY, Park SY
- KMID: 2500325
- Cancer Res Treat.
- 2020 Apr;52(2):396-405.
- doi: 10.4143/crt.2019.152
Purpose High rate of false-positive tests is a major obstacle to use human papillomavirus (HPV) detection as a diagnostic tool for high-grade squamous intraepithelial lesions or cervical cancer (HSIL+). We investigated whether type-specific... -
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- Pretreatment Lymph Node Metastasis as a Prognostic Significance inCervical Cancer: Comparison between Disease Status
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Jeong SY, Park H, Kim MS, Kang JH, Paik ES, Lee YY, Kim TJ, Lee JW, Kim BG, Bae DS, Choi CH
- KMID: 2500336
- Cancer Res Treat.
- 2020 Apr;52(2):516-523.
- doi: 10.4143/crt.2019.328
Purpose Lymph node metastasis (LNM) is the most significant prognostic factor in cervical cancer that was recently incorporated into the International Federation of Gynecology and Obstetrics (FIGO) staging system. This study was performed... -
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- Clinical Impact of Somatic Variants in Homologous RecombinationRepair-Related Genes in Ovarian High-Grade Serous Carcinoma
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Choi MC, Hwang S, Kim S, Jung SG, Park H, Joo WD, Song SH, Lee C, Kim TH, Kang H, An HJ
- KMID: 2500347
- Cancer Res Treat.
- 2020 Apr;52(2):634-644.
- doi: 10.4143/crt.2019.207
Purpose In this study, we investigated the frequencies of mutations in DNA damage repair genes including BRCA1, BRCA2, homologous recombination genes and TP53 gene in ovarian highgrade serous carcinoma, alongside those of germline... -
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- Detection of Targetable Genetic Alterations in Korean Lung CancerPatients: A Comparison Study of Single-Gene Assays andTargeted Next-Generation Sequencing
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Park E, Shim HS
- KMID: 2500339
- Cancer Res Treat.
- 2020 Apr;52(2):543-551.
- doi: 10.4143/crt.2019.305
Purpose Epidermal growth factor receptor (EGFR), anaplastic lymphoma kinase (ALK), and ROS proto-oncogene 1 (ROS1) are ‘must-test’ biomarkers in the molecular diagnostics of advanced- stage lung cancer patients. Although single-gene assays are currently... -
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- Validation of the 8th Edition of the American Joint Committee onCancer Staging System for Gallbladder Cancer and Implications forthe Follow-up of Patients without Node Dissection
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Sung YN, Song M, Lee JH, Song KB, Hwang DW, Ahn CS, Hwang S, Hong SM
- KMID: 2500331
- Cancer Res Treat.
- 2020 Apr;52(2):455-468.
- doi: 10.4143/crt.2019.271
Purpose The 8th edition of gallbladder cancer staging in the American Joint Committee on Cancer (AJCC) staging system changed the T and N categories. Materials and Methods In order to validate the new staging... -
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- Association of Body Composition with Long-Term Survival inNon-metastatic Rectal Cancer Patients
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Han JS, Ryu H, Park IJ, Kim KW, Shin Y, Kim SO, Lim SB, Kim CW, Yoon YS, Lee JL, Yu CS, Kim JC
- KMID: 2500341
- Cancer Res Treat.
- 2020 Apr;52(2):563-572.
- doi: 10.4143/crt.2019.249
Purpose We evaluated the association of body composition with long-term oncologic outcomes in non-metastatic rectal cancer patients. Materials and Methods We included 1,384 patients with stage(y)0-III rectal cancer treated at Asan Medical Center between January... -
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- Impact of Angiotensin Receptor Blockers, Beta Blockers,Calcium Channel Blockers and Thiazide Diuretics on Survivalof Ovarian Cancer Patients
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Cho MA, Jeong SY, Sohn I, Kim MS, Kang JH, Paik ES, Lee YY, Choi CH
- KMID: 2500348
- Cancer Res Treat.
- 2020 Apr;52(2):645-654.
- doi: 10.4143/crt.2019.509
Purpose We investigated the impact of four types of antihypertensive medications, angiotensin receptor blockers (ARBs), beta blockers (BBs; both selective and non-selective), calcium channel blockers (CCBs), and thiazide diuretics (TDs) on survival outcomes... -
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- An Integrated Nomogram Combining Clinical Factors andMicrotubule-Associated Protein 1 Light Chain 3B Expression to PredictPostoperative Prognosis in Patients with Intrahepatic Cholangiocarcinoma
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Chen L, Fu H, Lu T, Cai J, Liu W, Yao J, Liang J, Zhao H, Zhang J, Zheng J, Zhang Y, Yang Y
- KMID: 2500332
- Cancer Res Treat.
- 2020 Apr;52(2):469-480.
- doi: 10.4143/crt.2019.423
Purpose Microtubule-associated protein 1 light chain 3B (LC3B) serves as a key component of autophagy, which is associated with the progression of carcinoma. Yet, it is still unclear whether LC3B is also an... -
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- Activation of Tyrosine Metabolism in CD13+ Cancer Stem Cells DrivesRelapse in Hepatocellular Carcinoma
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Sun L, Zhang L, Chen J, Li C, Sun H, Wang J, Xiao H
- KMID: 2500345
- Cancer Res Treat.
- 2020 Apr;52(2):604-621.
- doi: 10.4143/crt.2019.444
Purpose Cancer stem cells (CSCs) are naturally resistant to chemotherapy, explaining why tumor relapse frequently occurs after initial regression upon administration of chemotherapeutic agents in most cases. A CSC population characterized by CD13... -
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- Displacement of Surgical Clips in Patients with Human AcellularDermal Matrix in the Excision Cavity during Whole Breast IrradiationFollowing Breast-Conserving Surgery
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Jung W, Kim K, Paik NS
- KMID: 2500324
- Cancer Res Treat.
- 2020 Apr;52(2):388-395.
- doi: 10.4143/crt.2019.213
Purpose The purpose of this study was to investigate the displacement of surgical clips in the excision cavity during whole breast irradiation following breast-conserving surgery (BCS) with or without acellular dermal matrix (ADM)... -
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- A Radiosensitivity Gene Signature and PD-L1 Status Predict ClinicalOutcome of Patients with Glioblastoma Multiforme in The CancerGenome Atlas Dataset
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Jang BS, Kim IA
- KMID: 2500338
- Cancer Res Treat.
- 2020 Apr;52(2):530-542.
- doi: 10.4143/crt.2019.440
Purpose Combination of radiotherapy and immune checkpoint blockade such as programmed death- 1 (PD-1) or programmed death-ligand 1 (PD-L1) blockade is being actively tested in clinical trial. We aimed to identify a subset... -
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