- Skeletal Muscle Thermogenesis and Its Role in Whole Body Energy Metabolism
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Periasamy , Herrera JL, Reis FC
- KMID: 2392475
- Diabetes Metab J.
- 2017 Oct;41(5):327-336.
- doi: 10.4093/dmj.2017.41.5.327
Obesity and diabetes has become a major epidemic across the globe. Controlling obesity has been a challenge since this would require either increased physical activity or reduced caloric intake; both... -
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- Effects of NaOCl on Neuronal Excitability and Intracellular Calcium Concentration in Rat Spinal Substantia Gelatinosa Neurons
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Lee HI, Park AR, Chun SW
- KMID: 1431123
- Int J Oral Biol.
- 2013 Mar;38(1):5-12.
Recent studies indicate that reactive oxygen species (ROS) can act as modulators of neuronal activity, and are critically involved in persistent pain primarily through spinal mechanisms. In this study, we... -
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- Peptidoglycan Induces the Production of Interleukin-8 via Calcium Signaling in Human Gingival Epithelium
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Son A, Shin DM, Hong JH
- KMID: 2071819
- Korean J Physiol Pharmacol.
- 2015 Jan;19(1):51-57.
- doi: 10.4196/kjpp.2015.19.1.51
The etiology of periodontal disease is multifactorial. Exogenous stimuli such as bacterial pathogens can interact with toll-like receptors to activate intracellular calcium signaling in gingival epithelium and other tissues. The... -
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- Role of Regulators of G-Protein Signaling 4 in Ca2+ Signaling in Mouse Pancreatic Acinar Cells
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Park S, Lee SI, Shin DM
- KMID: 2285425
- Korean J Physiol Pharmacol.
- 2011 Dec;15(6):383-388.
- doi: 10.4196/kjpp.2011.15.6.383
Regulators of G-protein signaling (RGS) proteins are regulators of Ca2+ signaling that accelerate the GTPase activity of the G-protein alpha-subunit. RGS1, RGS2, RGS4, and RGS16 are expressed in the pancreas,... -
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- Role of calcium channels responsible for phenylephrine-induced contraction in rat aorta 3 days after acute myocardial infarction
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Kim JE, Choi BK, Choi JY, Ryu T, Roh WS, Song SY
- KMID: 2092435
- Korean J Anesthesiol.
- 2014 Feb;66(2):143-152.
- doi: 10.4097/kjae.2014.66.2.143
BACKGROUND: Phenylephrine (PE) produces tonic contraction through involvement of various calcium channels such as store-operated calcium channels (SOCCs) and voltage-operated calcium channels (VOCCs). However, the relative contribution of each calcium... -
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- Effect of Hypoxic Paracrine Media on Calcium-Regulatory Proteins in Infarcted Rat Myocardium
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Song BW, Hwang HJ, Seung M, Lee MH
- KMID: 1859237
- Korean Circ J.
- 2014 Jan;44(1):16-21.
- doi: 10.4070/kcj.2014.44.1.16
BACKGROUND AND OBJECTIVES: An increase in intracellular calcium concentration due to loss of Ca2+ homeostasis triggers arrhythmia or cardiac cell death in the heart. Paracrine factors released from stem cells... -
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- Efffects of Fluoxetine on ATP-induced Calcium Signaling in PC12 Cells
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Lee YM, Kim HJ, Hong SH, Kim MJ, Min DS, Rhie DJ, Kim MS, Jo YH, Hahn SJ, Yoon SH
- KMID: 1517038
- Korean J Physiol Pharmacol.
- 2004 Feb;8(1):57-63.
Fluoxetine, a widely used anti-depressant compound, has several additional effects, including blockade of voltage-gated ion channels. We examined whether fluoxetine affects ATP-induced calcium signaling in PC12 cells by using fura-2-based... -
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- Calcium Uptake and Release through Sarcoplasmic Reticulum in the Inferior Oblique Muscles of Patients with Inferior Oblique Overaction
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Kim HS, Chang YH, Kim DH, Park SR, Han SH, Lee JB
- KMID: 1110744
- Yonsei Med J.
- 2006 Apr;47(2):207-213.
- doi: 10.3349/ymj.2006.47.2.207
We characterized and compared the characteristics of Ca2+ movements through the sarcoplasmic reticulum of inferior oblique muscles in the various conditions including primary inferior oblique overaction (IOOA), secondary IOOA, and... -
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- Unchanged protein level of ryanodine receptor but reduced (3H) ryanodine binding of cardiac sarcoplasmic reticulum from diabetic cardiomyopathy rats
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Lee EH, Seo YJ, Kim YH, Kim HW
- KMID: 1607079
- Korean J Physiol Pharmacol.
- 2001 Oct;5(5):397-405.
The ryanodine receptor, a Ca2+ release channel of the sarcoplasmic reticulum (SR), is responsible for the rapid release of Ca2+ that activates cardiac muscle contraction. In the excitation-contraction coupling cascade, activation of SR... -
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- An Angiotensin Receptor Blocker Prevents Arrhythmogenic Left Atrial Remodeling in a Rat Post Myocardial Infarction Induced Heart Failure Model
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Kim HS, No CW, Goo SH, Cha TJ
- KMID: 1777557
- J Korean Med Sci.
- 2013 May;28(5):700-708.
- doi: 10.3346/jkms.2013.28.5.700
This study investigated the role of angiotensin II receptor blocker in atrial remodeling in rats with atrial fibrillation (AF) induced by a myocardial infarction (MI). MIs were induced by a... -
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- Hydrogen peroxide inhibits Ca²⺠efflux through plasma membrane Ca²âº-ATPase in mouse parotid acinar cells
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Kim MJ, Choi KJ, Yoon MN, Oh SH, Kim DK, Kim SH, Park HS
- KMID: 2410111
- Korean J Physiol Pharmacol.
- 2018 Mar;22(2):215-223.
- doi: 10.4196/kjpp.2018.22.2.215
Intracellular Ca²⺠mobilization is closely linked with the initiation of salivary secretion in parotid acinar cells. Reactive oxygen species (ROS) are known to be related to a variety of oxidative... -
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- Effects of Reactive Oxygen Species on ATP-induced intracellular Ca2+ Activity in Osteoblasts
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Kim JH, Kwon TD, Nam SH, Suh CK, Hong YW
- KMID: 1860817
- Korean J Anesthesiol.
- 2003 Apr;44(4):544-554.
- doi: 10.4097/kjae.2003.44.4.544
BACKGORUND: The physiological activity of osteoblsts is known to be closely related to increased intracellular Ca2+ activity ([Ca2+ ]i) in osteoblasts. The cellular regulation of ([Ca2+ ]i) in osteoblasts... -
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- alpha-Mangostin Reduced ER Stress-mediated Tumor Growth through Autophagy Activation
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Kim SJ, Hong EH, Lee BR, Park MH, Kim JW, Pyun AR, Kim YJ, Chang SY, Chin YW, Ko HJ
- KMID: 2150757
- Immune Netw.
- 2012 Dec;12(6):253-260.
- doi: 10.4110/in.2012.12.6.253
alpha-Mangostin is a xanthon derivative contained in the fruit hull of mangosteen (Garcinia mangostana L.), and the administration of alpha-Mangostin inhibited the growth of transplanted colon cancer, Her/CT26 cells which... -
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- Mechanism of Leptin-Induced Potentiation of Catecholamine Secretion Evoked by Cholinergic Stimulation in the Rat Adrenal Medulla
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Lim DY, Choi DH, Kang MJ
- KMID: 1611351
- Korean J Physiol Pharmacol.
- 2004 Aug;8(4):227-235.
The aim of the present study was to examine the effect of leptin on CA release from the isolated perfused model of the rat adrenal gland, and to establish its... -
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- D-Amphetamine Causes Dual Actions on Catecholamine Release from the Rat Adrenal Medulla
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Lim GH, Na GM, Min SY, Seo YS, Park CW, Lim DY
- KMID: 2285309
- Korean J Physiol Pharmacol.
- 2005 Feb;9(1):45-53.
The present study was designed to examine the effect of d-amphetamine on CA release from the isolated perfused model of the rat adrenal gland, and to establish its mechanism of... -
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- Inhibitory effect of Suaeda asparagoides (Miq.) extract on the motility of rat gastric antrum is mediated by beta-adrenoceptor
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Endale M, Song JC, Rhee MH, Liu KH, Kim TK, Kwon JG, Park KS, Chung KM, Kim TW
- KMID: 1444964
- Lab Anim Res.
- 2011 Dec;27(4):317-325.
- doi: 10.5625/lar.2011.27.4.317
Suaeda asparagoides (Miq.) has long been used as a Korean folk herbal medicine for the treatment of functional gastrointestinal disorders. However, reports on its pharmacological activity on gastrointestinal motility are... -
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- Effects of Inositol 1,4,5-triphosphate on Osteoclast Differentiation in RANKL-induced Osteoclastogenesis
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Son A, Kim MS, Jo H, Byun HM, Shin DM
- KMID: 2285437
- Korean J Physiol Pharmacol.
- 2012 Feb;16(1):31-36.
- doi: 10.4196/kjpp.2012.16.1.31
The receptor activator of NF-kappaB ligand (RANKL) signal is an activator of tumor necrosis factor receptor-associated factor 6 (TRAF6), which leads to the activation of NF-kappaB and other signal transduction... -
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- Myricetin Protects Against High Glucose-Induced β-Cell Apoptosis by Attenuating Endoplasmic Reticulum Stress via Inactivation of Cyclin-Dependent Kinase 5
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Karunakaran U, Elumalai S, Moon JS, Jeon JH, Kim ND, Park KG, Won KC, Leem J, Lee IK
- KMID: 2442772
- Diabetes Metab J.
- 2019 Apr;43(2):192-205.
- doi: 10.4093/dmj.2018.0052
BACKGROUND: Chronic hyperglycemia has deleterious effects on pancreatic β-cell function and turnover. Recent studies support the view that cyclin-dependent kinase 5 (CDK5) plays a role in β-cell failure under hyperglycemic... -
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- Alteration of Expression of Ca(2+) Signaling Proteins and Adaptation of Ca(2+) Signaling in SERCA2(+/-) Mouse Parotid Acini
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Choi JH, Jo H, Hong JH, Lee SI, Shin DM
- KMID: 1084506
- Yonsei Med J.
- 2008 Apr;49(2):311-321.
- doi: 10.3349/ymj.2008.49.2.311
PURPOSE: The sarco/endoplasmic reticulum Ca(2+)-ATPase (SERCA), encoded by ATP2A2, is an essential component for G-protein coupled receptor (GPCR)-dependent Ca(2+) signaling. However, whether the changes in Ca(2+) signaling and Ca(2+) signaling... -
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