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Vaccination of goats with a combination Salmonella vector expressing four Brucella antigens (BLS, PrpA, Omp19, and SOD) confers protection against Brucella abortus infection

Leya M, Kim WK, Cho JS, Yu EC, Kim YJ, Yeo Y, Lyoo KS, Yang MS, Han SS, Lee JH, Tark D, Hur J, Kim B

Salmonella is an intracellular pathogen with a cellular infection mechanism similar to that of Brucella, making it a suitable choice for use in an anti-Brucella immune boost system. This study...
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Different invasion efficiencies of Brucella abortus wild-type and mutantsin RAW 264.7 and THP-1 phagocytic cells and HeLa non-phagocytic cells

Shim S, Im YB, Jung M, Park WB, Yoo HS

Brucellosis is one of the common zoonoses caused by Brucella abortus (B. abortus). However, little has been reported on factors affecting invasion of B. abortus into host cells. To investigate...
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Analysis of protein expression in Brucella abortus mutants with different growth rates by two-dimensional gel electrophoresis and LC-MS/MS peptide analysis

Park WB, Im YB, Shim S, Yoo HS

Brucella abortus is a bacterium that causes brucellosis and is the causative agent of worldwide zoonoses. Pathogenesis of the B. abortus infection is complicated, and several researchers have attempted to...
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Tannic acid-mediated immune activation attenuates Brucella abortus infection in mice

Reyes AW, Hop HT, Arayan LT, Huy TX, Min W, Lee HJ, Chang HH, Kim S

Brucellosis is an emerging infectious disease affecting humans and animals. In this study, we investigated the in vitro and in vivo effects of tannic acid (TA) against Brucella abortus infection....
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A Novel PCR Assay for Detecting Brucella abortus and Brucella melitensis

Alamian S, Esmaelizad M, Zahraei T, Etemadi A, Mohammadi , Afshar D, Ghaderi S

OBJECTIVES: Brucellosis is a major zoonotic disease that poses a significant public health threat worldwide. The classical bacteriological detection process used to identify Brucella spp. is difficult and time-consuming. This...
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Isolation and characterization of Brucella abortus isolates from wildlife species in South Korea

Truong QL, Kim K, Kim JT, Her M, Jung SC, Hahn TW

A total of 782 blood and 465 tissue samples from 1,039 wild animals and 127 dairy goats were collected from January 2011 to December 2013 in 10 provinces of South...
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In silico analysis of Brucella abortus Omp2b and in vitro expression of SOmp2b

Golshani M, Vaeznia N, Sahmani M, Bouzari S

PURPOSE: At present, there is no vaccine available for the prevention of human brucellosis. Brucella outer membrane protein 2b (Omp2b) is a 36 kD porin existed in common Brucella pathogens...
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Immunization of BALB/c mice with Brucella abortus 2308DeltawbkA confers protection against wild-type infection

Li ZQ, Gui D, Sun ZH, Zhang JB, Zhang WZ, Zhang H, Guo F, Chen CF

Brucellosis is a zoonotic disease that causes animal and human diseases. Vaccination is a major measure for prevention of brucellosis, but it is currently not possible to distinguish vaccinated animals...
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Successful Medical Treatment of Prosthetic Mitral Valve Endocarditis Caused by Brucella abortus

Lee SA, Kim KH, Shin HS, Lee HS, Choi HM, Kim HK

Although Brucella endocarditis is a rare complication of human brucellosis, it is the main cause of the mortality in this disease. Traditionally, the therapeutic approach to endocarditis caused by Brucella...
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Therapeutic effects of combination of Galla rhois extract and Sodium chlorate on Mice infected with Brucella abortus

Cha CN, Hong IH, Yu EA, Park EK, Yoo CY, Kim S, Lee HJ

  • KMID: 2168981
  • J Biomed Res.
  • 2014 Mar;15(1):1-6.
This study investigated the therapeutic effects of Galla rhois (GR) ethanol extract (GRE), sodium chlorate (SC), and a combination of GRE and SC on mice infected with Brucella abortus (B....
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Spontaneous Bacterial Peritonitis due to Brucella abortus in a Cirrhotic Patient in Jeju Island

Heo ST, Cho YK, Kim YR, Lee KH, Yoon JW, Ko KS, Park MY, Choi YS

  • KMID: 2054334
  • Infect Chemother.
  • 2007 Feb;39(1):54-58.
Spontaneous bacterial peritonitis is the common infectious disease in liver cirrhosis patients with a fever. Brucellosis is a rare cause of bacterial peritonitis. A case indigenous to a citizen of...
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Identification of Brucella abortus using the sequencing of omp gene

Lee YJ, Ko KS, Park MY, Oh WS, Kwon KT, Ryu SY, Heo ST, Peck KR, Lee NY, Song JH

  • KMID: 2256646
  • Korean J Med.
  • 2006 Jul;71(1):10-16.
BACKGROUND: As the incidence of bovine brucellosis increases in Korea, the incidence of human brucellosis is also increasing since 2002. However, it is difficult to identify Brucella species by using...
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Diversity of Humoral Immune Responses to Recombinant Proteins of Brucella abortus Among Residents in Cheju Province

Euh HJ, Yeom JS, Kim JM, Kim JD, Cho SN

  • KMID: 2099369
  • J Korean Soc Microbiol.
  • 2000 Oct;35(5):377-377.
No Abstract Available.
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