Korean J Parasitol.  1998 Dec;36(4):281-284. 10.3347/kjp.1998.36.4.281.

Verification of immunosuppression in chicks caused by Cryptosporidium baileyi infection using Brucella abortus strain 1119-3

• Rhee JK
• Yang HJ
• Kim HC

• KMID: 1715296
• DOI: http://doi.org/10.3347/kjp.1998.36.4.281

Abstract

Humoral immune response of young chicks to Brucella abortus strain 1119-3 inoculation was monitored to verify the degree of immunosuppression caused by infection with Cryptosporidium baileyi. Young chicks (2-day-old) were orally inoculated each with 2 x 10(6) oocysts of C. baileyi, and then injected intramuscularly with 0.3 ml B. abortus strain 1119-3 containing 1 x 10(9) living organisms on day 14 postinoculation (PI). Serum samples were tested by plate agglutination test on day 17 PI onwards at an interval of 3-6 days over a period of 36 days. Infected chicks with the coccidium showed significantly lower antibody titers than those of uninfected controls (P < 0.05). These findings document that C. baileyi infection in early life stage may predispose chicks easily to other potential poultry diseases.

MeSH Terms

Animal
Antibodies, Bacterial/analysis
Antibody Formation
Brucella abortus/immunology*
Chickens
Cryptosporidiosis/immunology*
Immune Tolerance*