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Melatonin modulates nitric oxide-regulated WNK-SPAK/OSR1-NKCC1 signaling in dorsal raphe nucleus of rats

Yang HJ, Kim MJ, Kim SS, Cho YW

The sleep-wake cycle is regulated by the alternating activity of sleep- and wake-promoting neurons. The dorsal raphe nucleus (DRN) secretes 5-hydroxytryptamine (5-HT, serotonin), promoting wakefulness. Melatonin secreted from the pineal...
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Prediction of COVID-19-related Mortality and 30-Day and 60-Day Survival Probabilities Using a Nomogram

Moon Hj, Kim K, Kang EK, Yang HJ, Lee E

Background: Prediction of mortality in patients with coronavirus disease 2019 (COVID-19) is a key to improving the clinical outcomes, considering that the COVID-19 pandemic has led to the collapse of...
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Respiratory Protection Effect of Earloop-type KF94 Masks according to the Wearing Method in COVID-19 Pandemic: a Randomized, Open-label Study

Yang HJ, Yoon H, Kang SY, Lee G, Park JE, Kim T, Lee SU, Hwang SY, Cha WC, Shin TG, Jo IJ

Background: Ear-loop-type Korean Filter 94 masks (KF94 masks, equivalent to the N95 and FFP2) are broadly used in health care settings in Korea for the coronavirus disease 2019 pandemic. Methods: A...
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A Mixed Method Study for Exploring the Difficulties in End-of-Life Care and End-of-Life Care Competency in Nurses Who Take Care of Cancer Patients

Kim LH, Kim SY, Kim S, Kim HA, Yang HJ, Lee KM, Lee SY, Lee KH, Kim JH

Purpose: This study investigated the difficulties in end-of-life care and end-of-life care competency in nurses who take care of cancer patients. Methods: In the mixed method, a structured questionnaire on...
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Metabolically Healthy Obesity Is Associated with an Increased Risk of Colorectal Adenoma Occurrence Diagnosed by Surveillance Colonoscopy

Chae H, Yang HJ, Park SK, Jung YS, Park JH, Park DI, Sohn CI

Background/Aims: The risk of recurrence of colorectal adenoma among obese individuals without metabolic abnormalities or in those with metabolically healthy obesity is largely unexplored.Therefore, we longitudinally investigated the risk of...
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Endoscopic Treatment for Superficial Nonampullary Duodenal Tumors

Yang HJ

Superficial nonampullary duodenal epithelial tumors are considered rare but have been increasingly recognized in recent years. Accordingly, the importance of endoscopic treatment for the lesions are also increasing. An endoscopic resection...
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Association between Maternal Adverse Childhood Experiences and Risk of Post-traumatic Stress Disorder in the Offspring

Na MC, Kim MD, Park JH, Jung YE, Moon DS, Yang HJ, Kim BN, Kang NR

Objectives: Adverse childhood experiences (ACEs) of mothers may negatively affect the mental health of their offspring. Little is known about the intergenerational effect of maternal ACE on post-traumatic stress disorder...
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Evidence-Based Guidelines for the Treatment of Helicobacter pylori Infection in Korea 2020

Jung HK, Kang SJ, Lee YC, Yang HJ, Park SY, Shin CM, Kim SE, Lim HC, Kim JH, Nam SY, Shin WG, Park JM, Choi IJ, Kim JG, Choi M, Korean College of Helicobacter and Upper Gastrointestinal Research

Helicobacter pylori infection is one of the most common infectious diseases worldwide. Although the prevalence of H. pylori is gradually decreasing, approximately half of the world's population still becomes infected...
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A Case of New-Onset Vitiligo in a Healthy Volunteer After Administration of Adalimumab

Yang HJ, Lee WJ, Lee MW, Choi JH, Chang SE

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Deep Neural Network-Based Prediction of the Risk of Advanced Colorectal Neoplasia

Min JK, Yang HJ, Kwak MS, Cho CW, Kim S, Ahn KS, Park SK, Cha JM, Park DI

Background/Aims: Risk prediction models using a deep neural network (DNN) have not been reported to predict the risk of advanced colorectal neoplasia (ACRN). The aim of this study was to...
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Longevity of Cross-linked Hyaluronic Acid Filler Depending on Injection Depth: In Vivo Study Using a Small Animal Model

Lee WJ, Choi ME, Lee KH, Yang HJ, Kang HJ, Won KH, Won CH

  • KMID: 2506582
  • Korean J Dermatol.
  • 2020 Sep;58(8):516-524.
Background: Hyaluronic acid (HA) is the material used most often for soft tissue augmentation. Both agent factors, such as type of fillers and host factors, including technical manipulation, are known...
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Clinical Guidelines for Drug-induced Peptic Ulcer, 2020 Revised Edition

Joo MK, Park CH, Kim JS, Park JM, Ahn JY, Lee BE, Lee JH, Yang HJ, Cho YK, Bang CS, Kim BJ, Jung HK, Kim BW, Lee YC, Korean College of Helicobacter and Upper Gastrointestinal Research

The Korean guidelines for nonsteroidal anti-inflammatory drug (NSAID)-induced peptic ulcers were previously developed under co-work with the Korean College of Helicobacter and Upper Gastrointestinal Research and Korean Society of Gastroenterology...
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Monitoring Tumor Size Using PET with a Collimator during Boron Neutron Capture Therapy: Simulation Study

Yang HJ, Yoon DK, Suh TS

  • KMID: 2510100
  • Prog Med Phys.
  • 2020 Sep;31(S1):S55.
Purpose: The purpose of this study was to demonstrate the feasibility of sensing changes in a tumor during boron neutron capture therapy (BNCT) using a Monte Carlo simulation tool. Methods: In...
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Statistical Analysis for Determining Initial Electron Beam Parameters in a 6MV Linac: A Simulation Study

Yang HJ, Kim TH, Schaarschmidt T, Park DW, Chung HT, Suh TS

  • KMID: 2510098
  • Prog Med Phys.
  • 2020 Sep;31(S1):S54.
Purpose: The purpose of this study was to obtain the initial electron beam parameters of a medical linear accelerator (Linac) with Monte Carlo (MC) simulations using the Geant4 code. The...
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Helicobacter pylori Eradication Can Reverse the Methylation-Associated Regulation of miR-200a/b in Gastric Carcinogenesis

Choi JM, Kim SG, Yang HJ, Lim JH, Cho NY, Kim WH, Kim JS, Jung HC

Background/Aims: Epigenetic change is one of the mecha- nisms that regulates the expression of microRNAs (miRNAs) and is known to play a role in Helicobacter pylori-associated gastric carcinogenesis. We aimed to...
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Effects of alcohol intake on the severity of injuries during riding a bicycle

Seo MJ, Cho JS, Lim YS, Yang HJ, Woo JH, Choi WS

  • KMID: 2506062
  • J Korean Soc Emerg Med.
  • 2020 Aug;31(4):355-361.
Objective: When bike riding under the influence of alcohol, incidence of injury increases, although reports of highly severe injuries is rare. Therefore, this study aimed to determine how drinking alcohol...
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Predictors of Retinal Pigment Epithelial Tears in Exudative Macular Degeneration with High Pigment Epithelial Detachment

Yang HJ, Kim KS

Purpose: To evaluate the risk factors for retinal pigment epithelium (RPE) tear after intravitreal anti-vascular endothelial growth factor treatment in patients with exudative age-related macular degeneration, associated with high pigment...
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Sixth Cranial Nerve Palsy and Vertigo Caused by Vertebrobasilar Insufficiency

Paik SW, Yang HJ, Seo YJ

A 38-year-old woman presented with a week’s history of binocular horizontal double vision and acute vertigo with gaze-induced nystagmus. We considered a diagnosis of one of the six syndromes of...
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Cereblon Deletion Ameliorates Lipopolysaccharide-induced Proinflammatory Cytokines through 5′-Adenosine Monophosphate-Activated Protein Kinase/Heme Oxygenase-1 Activation in ARPE-19 Cells

Kim YK, Chae SC, Yang HJ, An DE, Lee S, Yeo MG, Lee KJ

Cereblon (CRBN), a negative modulator of AMP-activated protein kinase (AMPK), is highly expressed in the retina. We confirmed the expression of CRBN in ARPE-19 human retinal cells by Western blotting....
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Helicobacter pylori Eradication Therapy to Prevent Gastric Cancer in First-degree Relatives of Gastric Cancer Patient

Yang HJ

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