- Human B1 Cells are the Main Blood Group A-Specific B Cells That Have a Moderate Correlation With Anti-A Antibody Titer
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Xu Y, Lee JG, Yan JJ, Ryu JH, Xu S, Yang J
- KMID: 2457493
- Ann Lab Med.
- 2020 Jan;40(1):48-56.
- doi: 10.3343/alm.2020.40.1.48
BACKGROUND: Anti-carbohydrate antibody responses, including those of anti-blood group ABO antibodies, are yet to be thoroughly studied in humans. Because anti-ABO antibody-mediated rejection is a key hurdle in ABO-incompatible transplantation,... -
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- The Eschar Size and Early Inoculation Lesion of Tsutsugamushi Disease on Jeju Island, Korea
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Kim YH, Hyun W, Kim DP, Chung MH, Im JH, Baek JH, Lee JS, Kang JS
- KMID: 2466467
- Infect Chemother.
- 2019 Dec;51(4):345-354.
- doi: 10.3947/ic.2019.51.4.345
BACKGROUND: Tsutsugamushi disease, or scrub typhus, is an acute febrile illness caused by Orientia tsutsugamushi, which is followed by chronic latent infection. People who reside in areas endemic of tsutsugamushi... -
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- A phase 1/2a, dose-escalation, safety and preliminary efficacy study of oral therapeutic vaccine in subjects with cervical intraepithelial neoplasia 3
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Park YC, Ouh YT, Sung MH, Park HG, Kim TJ, Cho CH, Park JS, Lee JK
- KMID: 2458895
- J Gynecol Oncol.
- 2019 Nov;30(6):e88.
- doi: 10.3802/jgo.2019.30.e88
OBJECTIVE: Persistent infection of HPV increases the chance of carcinoma in situ of cervix through stages of cervical intraepithelial neoplasia (CIN) 1, 2, and 3, and finally progresses into cervical... -
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- Virus-like Particle Vaccine Containing Toxoplasma gondii Rhoptry Protein 13 Induces Protection against T. gondii ME49 Infection in Mice
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Kang HJ, Chu KB, Lee SH, Kim MJ, Park H, Jin H, Quan FS
- KMID: 2463745
- Korean J Parasitol.
- 2019 Oct;57(5):543-547.
- doi: 10.3347/kjp.2019.57.5.543
Toxoplasma gondii can infect humans worldwide, causing serious diseases in pregnant women and immunocompromised individuals. T. gondii rhoptry protein 13 (ROP13) is known as one of the key proteins involved... -
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- Curcumin Elevates T(FH) Cells and Germinal Center B Cell Response for Antibody Production in Mice
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Kim DH, Lee HG, Choi JM
- KMID: 2461199
- Immune Netw.
- 2019 Oct;19(5):e35.
- doi: 10.4110/in.2019.19.e35
Curcumin is a natural product extracted from Curcuma longa. It has been reported as a potent antioxidant and anti-inflammatory compound. Previous studies have demonstrated that curcumin suppresses pro-inflammatory cytokine production... -
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- Antibody responses after vaccination against equine influenza in Korea in 2016–2018
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- KMID: 2461012
- Korean J Vet Res.
- 2019 Sep;59(3):151-155.
- doi: 10.14405/kjvr.2019.59.3.151
Equine influenza (EI) is the main cause of respiratory illness in equines across the globe and is caused by equine influenza A virus (EIV-A), which has impacted the equine industry... -
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- Effect of simultaneous administration of foot-and-mouth disease (FMD) and anthrax vaccines on antibody response to FMD in sheep
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Çokçalışkan C, Tuncer Göktuna P, Türkoğlu T, Uzunlu E, Gündüzalp C, Uzun EA, Sareyyüpoğlu B, Kürkçü , Gülyaz V
- KMID: 2455081
- Clin Exp Vaccine Res.
- 2019 Jul;8(2):103-109.
- doi: 10.7774/cevr.2019.8.2.103
PURPOSE: Foot-and-mouth disease (FMD) and anthrax are important diseases in sheep. Vaccination is a favorable strategy against both infections. Simultaneous administration of vaccines does generally not impede the immune responses... -
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- Generation and protective efficacy of a cold-adapted attenuated genotype 2b porcine epidemic diarrhea virus
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Won H, Lee DU, Jang G, Noh YH, Lee SC, Choi HW, Yoon IJ, Yoo HS, Lee C
- KMID: 2453894
- J Vet Sci.
- 2019 Jul;20(4):e32.
- doi: 10.4142/jvs.2019.20.e32
The recent emergence and re-emergence of porcine epidemic diarrhea virus (PEDV) underscore the urgent need for the development of novel, safe, and effective vaccines against the prevailing strain. In this... -
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- Previous Infection with Plasmodium berghei Confers Resistance to Toxoplasma gondii Infection in Mice
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Lee DH, Chu KB, Kang HJ, Lee SH, Quan FS
- KMID: 2448140
- Korean J Parasitol.
- 2019 Apr;57(2):93-99.
- doi: 10.3347/kjp.2019.57.2.93
Both Plasmodium spp. and Toxoplasma gondii are important apicomplexan parasites, which infect humans worldwide. Genetic analyses have revealed that 33% of amino acid sequences of inner membrane complex from the... -
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- Advances in Serological Diagnosis of Taenia solium Neurocysticercosis in Korea
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Ahn CS, Kim JG, Huh S, Kang I, Kong Y
- KMID: 2447797
- Genomics Inform.
- 2019 Mar;17(1):e7.
- doi: 10.5808/GI.2019.17.1.e7
Cysticercosis, a parasitic disease caused by Taenia solium metacestode (TsM), has a major global public health impact in terms of disability-adjusted life years. The parasite preferentially infects subcutaneous tissue, but... -
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- Nucleoprotein vaccine induces cross-protective cytotoxic T lymphocytes against both lineages of influenza B virus
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Lee SY, Kang JO, Chang J
- KMID: 2438964
- Clin Exp Vaccine Res.
- 2019 Jan;8(1):54-63.
- doi: 10.7774/cevr.2019.8.1.54
PURPOSE: The influenza B virus diverges into two antigenically distinct lineages: B/Yamagata and B/Victoria. Influenza B is the dominant circulating virus during some influenza seasons, and recent data demonstrated that... -
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- Differential Hrd1 Expression and B-Cell Accumulation in Eosinophilic and Non-eosinophilic Chronic Rhinosinusitis With Nasal Polyps
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Chen K, Han M, Tang M, Xie Y, Lai Y, Hu X, Zhang J, Yang J, Li H
- KMID: 2441818
- Allergy Asthma Immunol Res.
- 2018 Nov;10(6):698-715.
- doi: 10.4168/aair.2018.10.6.698
PURPOSE: Hrd1 has recently emerged as a critical regulator of B-cells in autoimmune diseases. However, its role in the pathogenesis of chronic rhinosinusitis with nasal polyps (CRSwNP) remains largely unexplored.... -
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- Asthma has an adverse effect on the production of antibody to vaccines
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Sheen YH
- KMID: 2427485
- Allergy Asthma Respir Dis.
- 2018 Nov;6(6):279-283.
- doi: 10.4168/aard.2018.6.6.279
Asthma is considered a chronic inflammatory airway disease. Mounting evidence reports that patients with asthma are at significantly higher risk of developing communicable diseases such as invasive pneumococcal disease, Haemophilus... -
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- Comparison of immunoadjuvant activities of four bursal peptides combined with H9N2 avian influenza virus vaccine
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Zhang C, Zhou J, Liu Z, Liu Y, Cai K, Shen T, Liao C, Wang C
- KMID: 2427030
- J Vet Sci.
- 2018 Nov;19(6):817-826.
- doi: 10.4142/jvs.2018.19.6.817
The bursa of Fabricius (BF) is a central humoral immune organ unique to birds. Four bursal peptides (BP-I, BP-II, BP-III, and BP-IV) have been isolated and identified from the BF.... -
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- Virus-Like Particles Expressing Toxoplasma gondii Rhoptry Protein 18 Induces Better Protection Than Rhoptry Protein 4 against T. gondii Infection
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Kang HJ, Lee SH, Chu KB, Lee DH, Quan FS
- KMID: 2426747
- Korean J Parasitol.
- 2018 Oct;56(5):429-435.
- doi: 10.3347/kjp.2018.56.5.429
Toxoplasma gondii is a ubiquitous protozoan parasite responsible for causing toxoplasmosis. Preventive measures for toxoplasmosis are currently lacking and as such, development of novel vaccines are of urgent need. In... -
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- Expansion and Sub-Classification of T Cell-Dependent Antibody Responses to Encompass the Role of Innate-Like T Cells in Antibody Responses
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Park C, Kim TJ
- KMID: 2424200
- Immune Netw.
- 2018 Oct;18(5):e34.
- doi: 10.4110/in.2018.18.e34
In addition to T cell-dependent (TD) Ab responses, T cells can also regulate T cell-independent (TI) B cell responses in the absence of a specific major histocompatibility complex (MHC) class... -
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- Genetic identification and serological evaluation of commercial inactivated foot-and-mouth disease virus vaccine in pigs
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Je SH, Kwon T, Yoo SJ, Lee DU, Seo SW, Byun JJ, Shin JY, Lyoo YS
- KMID: 2418092
- Clin Exp Vaccine Res.
- 2018 Jul;7(2):139-144.
- doi: 10.7774/cevr.2018.7.2.139
Vaccination is considered a frequently used tool to prevent and control foot-and-mouth disease (FMD). However, the effectiveness of conventional FMD virus (FMDV) vaccines in pigs has been controversial because the... -
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- Purification and characterization of monoclonal IgG antibodies recognizing Ebola virus glycoprotein
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Han BS, Jang HY, Racine T, Qiu X, Sin JI
- KMID: 2418090
- Clin Exp Vaccine Res.
- 2018 Jul;7(2):119-128.
- doi: 10.7774/cevr.2018.7.2.119
PURPOSE: The goal of this study was to purify and characterize Ebola virus glycoprotein (GP)-specific IgG antibodies from hybridoma clones. MATERIALS AND METHODS: For hybridoma production, mice were injected by intramuscular-electroporation... -
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- Phenotypic and genotypic analyses of an attenuated porcine reproductive and respiratory syndrome virus strain after serial passages in cultured porcine alveolar macrophages
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Lee SC, Lee S, Yoo GW, Choi HW, Noh YH, Park CE, Shin JH, Yoon IJ, Kang SY, Lee C
- KMID: 2412126
- J Vet Sci.
- 2018 May;19(3):358-367.
- doi: 10.4142/jvs.2018.19.3.358
The porcine reproductive and respiratory syndrome virus (PRRSV) is a globally ubiquitous swine viral pathogen that causes major economic losses worldwide. We previously reported an over-attenuated phenotype of cell-adapted PRRSV... -
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- Safety and Immunogenicity of an Egg-Cultivated Quadrivalent Inactivated Split-virion Influenza Vaccine (GC3110A) in Healthy Korean Children: a Randomized, Double-blinded, Active-controlled Phase III Study
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Lee J, Lee KY, Kim JH, Kim CS, Eun BW, Kim HM, Kim DH, Hong YJ, Choi YY, Jo DS, Ma SH, Kang JH
- KMID: 2409210
- J Korean Med Sci.
- 2018 Mar;33(13):e100.
- doi: 10.3346/jkms.2018.33.e100
BACKGROUND: The frequency with which the 2 B lineages have been found to cocirculate in a season has been on the rise, which has spurred the need for a quadrivalent... -
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