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Diversity of Humoral Immune Responses to Recombinant Proteins of Brucella abortus Among Residents in Cheju Province

Euh HJ, Yeom JS, Kim JM, Kim JD, Cho SN

  • KMID: 2099369
  • J Korean Soc Microbiol.
  • 2000 Oct;35(5):377-377.
No Abstract Available.
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Different invasion efficiencies of Brucella abortus wild-type and mutantsin RAW 264.7 and THP-1 phagocytic cells and HeLa non-phagocytic cells

Shim S, Im YB, Jung M, Park WB, Yoo HS

Brucellosis is one of the common zoonoses caused by Brucella abortus (B. abortus). However, little has been reported on factors affecting invasion of B. abortus into host cells. To investigate...
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Successful Medical Treatment of Prosthetic Mitral Valve Endocarditis Caused by Brucella abortus

Lee SA, Kim KH, Shin HS, Lee HS, Choi HM, Kim HK

Although Brucella endocarditis is a rare complication of human brucellosis, it is the main cause of the mortality in this disease. Traditionally, the therapeutic approach to endocarditis caused by Brucella...
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A Novel PCR Assay for Detecting Brucella abortus and Brucella melitensis

Alamian S, Esmaelizad M, Zahraei T, Etemadi A, Mohammadi , Afshar D, Ghaderi S

OBJECTIVES: Brucellosis is a major zoonotic disease that poses a significant public health threat worldwide. The classical bacteriological detection process used to identify Brucella spp. is difficult and time-consuming. This...
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Brucella Endocarditis with Splenic Abscess: A Report of the First Case Diagnosed in Korea

Park SH, Choi YS, Choi YJ, Cho SH, Yoon HJ

Human brucellosis has a broad spectrum of clinical manifestations, which includes endocarditis, a focal complication that is uncommon yet responsible for the majority of associated deaths. The most successful treatment...
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Isolation and characterization of Brucella abortus isolates from wildlife species in South Korea

Truong QL, Kim K, Kim JT, Her M, Jung SC, Hahn TW

A total of 782 blood and 465 tissue samples from 1,039 wild animals and 127 dairy goats were collected from January 2011 to December 2013 in 10 provinces of South...
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Analysis of protein expression in Brucella abortus mutants with different growth rates by two-dimensional gel electrophoresis and LC-MS/MS peptide analysis

Park WB, Im YB, Shim S, Yoo HS

Brucella abortus is a bacterium that causes brucellosis and is the causative agent of worldwide zoonoses. Pathogenesis of the B. abortus infection is complicated, and several researchers have attempted to...
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Verification of immunosuppression in chicks caused by Cryptosporidium baileyi infection using Brucella abortus strain 1119-3

Rhee JK, Yang HJ, Kim HC

Humoral immune response of young chicks to Brucella abortus strain 1119-3 inoculation was monitored to verify the degree of immunosuppression caused by infection with Cryptosporidium baileyi. Young chicks (2-day-old)...
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Protective effects of recombinant Brucella abortus Omp28 against infection with a virulent strain of Brucella abortus 544 in mice

Lim JJ, Kim DH, Lee JJ, Kim DG, Min W, Lee HJ, Rhee MH, Kim S

The outer membrane proteins (OMPs) of Brucella (B.) abortus have been extensively studied, but their immunogenicity and protective ability against B. abortus infection are still unclear. In the present study,...
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In silico analysis of Brucella abortus Omp2b and in vitro expression of SOmp2b

Golshani M, Vaeznia N, Sahmani M, Bouzari S

PURPOSE: At present, there is no vaccine available for the prevention of human brucellosis. Brucella outer membrane protein 2b (Omp2b) is a 36 kD porin existed in common Brucella pathogens...
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The virulence of Brucella abortus isolated from cattle in Korea

Lim JJ, Kim JH, Kim DH, Lee JJ, Kim DG, Jun MH, Kim SH, Chang HH, Lee HJ, Min WG, Kim S

  • KMID: 1991810
  • Korean J Vet Res.
  • 2011 Mar;51(1):15-20.
In this study, we isolated 12 of Brucella (B.) spp. from cattle, which have been positive in Rose Bangal test and tube agglutination test in Gyeongbuk province in 2009. According...
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Brucella Epididymorchitis: A Rare Cause of Testicular Mass

Cha WH, Choi YS, Kim SW, Ha GY, Kim KH, Seo YJ, Lee KS

Brucellosis is a zoonosis, which is caused by Brucella abortus, B. melitensis, B. suis and B. canis. Brucellosis has been an emerging disease since the discovery of B. melitensis, by...
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Inhibitory effect of red ginseng acidic polysaccharide from Korean red ginseng on phagocytic activity and intracellular replication of Brucella abortus in RAW 264.7 cells

Bernardo Reyes AW, Simborio H, Hop HT, Arayan LT, Min WG, Lee HJ, Rhee MH, Chang HH, Kim S

Korean red ginseng (KRG) has long been used in traditional Korean and Oriental medicine. However, the anti-bacterial mechanism and therapeutic efficiency of KGR for intracellular Brucella infection are still unclear....
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Immunization of BALB/c mice with Brucella abortus 2308DeltawbkA confers protection against wild-type infection

Li ZQ, Gui D, Sun ZH, Zhang JB, Zhang WZ, Zhang H, Guo F, Chen CF

Brucellosis is a zoonotic disease that causes animal and human diseases. Vaccination is a major measure for prevention of brucellosis, but it is currently not possible to distinguish vaccinated animals...
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Vaccination of goats with a combination Salmonella vector expressing four Brucella antigens (BLS, PrpA, Omp19, and SOD) confers protection against Brucella abortus infection

Leya M, Kim WK, Cho JS, Yu EC, Kim YJ, Yeo Y, Lyoo KS, Yang MS, Han SS, Lee JH, Tark D, Hur J, Kim B

Salmonella is an intracellular pathogen with a cellular infection mechanism similar to that of Brucella, making it a suitable choice for use in an anti-Brucella immune boost system. This study...
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Efficacy of strain RB51 vaccine in protecting infection and vertical transmission against Brucella abortus in Sprague-Dawley rats

Islam MA, Khatun MM, Baek BK, Lee SI

Immunizing animals in the wild against Brucella (B.) abortus is essential to control bovine brucellosis because cattle can get the disease through close contact with infected wildlife. The aim of...
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Chemoprophylaxis and Serological Follow-Up in Brucella abortus Exposed Laboratory Workers

Lee CS, Lee HS, Lee JH, Park JH, Choi YS, Hwang KJ, Lee HB

The aerozolization is one of possible Brucella transmission mechanisms, particularly in air-borne exposed laboratory workers. In this study, seven laboratory workers were potentially exposed to B. abortus via aerosols. Two...
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Molecular cloning, purification and immunogenicity of recombinant Brucella abortus 544 malate dehydrogenase protein

Reyes AW, Simborio H, Hop HT, Arayan LT, Kim S

The Brucella mdh gene was successfully cloned and expressed in E. coli. The purified recombinant malate dehydrogenase protein (rMDH) was reactive to Brucella-positive bovine serum in the early stage, but...
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Identification of Brucella abortus using the sequencing of omp gene

Lee YJ, Ko KS, Park MY, Oh WS, Kwon KT, Ryu SY, Heo ST, Peck KR, Lee NY, Song JH

  • KMID: 2256646
  • Korean J Med.
  • 2006 Jul;71(1):10-16.
BACKGROUND: As the incidence of bovine brucellosis increases in Korea, the incidence of human brucellosis is also increasing since 2002. However, it is difficult to identify Brucella species by using...
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Investigation of a Series of Brucellosis Cases in Gyeongsangbuk-do during 2003-2004

Lim HS, Min YS, Lee HS

  • KMID: 792381
  • J Prev Med Public Health.
  • 2005 Nov;38(4):482-488.
OBJECTIVES: We conducted an investigation on 14 cases of brucellosis in Gyeongsangbuk-do during 2003-2004 to understand the source of infection and the transmission routes of brucellosis. METHODS: The authors visited the...
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