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From papyrus leaves to bioprinting and virtual reality: history and innovation in anatomy

Bisht B, Hope A, Paul MK

The human quest to master the anatomy and physiology of living systems started as early as 1600 BC, with documents from the Greeks, Indians, and Romans presenting the earliest systematic...
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Regenerative Medicine of the Bile Duct: Beyond the Myth

Buisson EM, Jeong J, Kim HJ, Choi D

Cholangiopathies are rare diseases of the bile duct with high mortality rates. The current treatment for cholangiopathies is liver transplantation, but there are significant obstacles including a shortage of donors...
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Development and Evaluation of Hyaluronic Acid-Based Hybrid Bio-Ink for Tissue Regeneration

Lee J, Lee SH, Kim BS, Cho YS, Park Y

BACKGROUND: Bioprinting has recently appeared as a powerful tool for building complex tissue and organ structures. However, the application of bioprinting to regenerative medicine has limitations, due to the restricted...
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Click Chemistry-Based Injectable Hydrogels and Bioprinting Inks for Tissue Engineering Applications

Gopinathan J, Noh I

BACKGROUND: The tissue engineering and regenerative medicine approach require biomaterials which are biocompatible, easily reproducible in less time, biodegradable and should be able to generate complex three-dimensional (3D) structures to...
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Application of Bioprinting to Cancer Research

Cho MJ, Chi BH, Kim MJ, Whang YM, Chang IH

Three-dimensional (3D) printing is an additive manufacturing process by which precursor materials are deposited layer by layer to form complex 3D geometries from computer-aided designs, and bioprinting offers the ability...
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Applications of kidney organoids derived from human pluripotent stem cells

Kim YK, Nam SA, Yang CW

The establishment of protocols to differentiate kidney organoids from human pluripotent stem cells provides potential applications of kidney organoids in regenerative medicine. Modeling of renal diseases, drug screening, nephrotoxicity testing...
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The Present and Future of the Cancer Microenvironment Bioprinting

Cho MJ, Chi BH, Kim MJ, Whang YM, Chang IH

Cancer is the tissue complex consisted with heterogeneous cellular compositions, and microenvironmental cues. During the various stages of cancer initiation, development, and metastasis, cell–cell interactions as well as cell-extracellular matrix...
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Three-Dimensional Cell-Based Bioprinting for Soft Tissue Regeneration

Kim JH, Yoo JJ, Lee SJ

Three-dimensional (3D) bioprinting technologies have been developed to offer construction of biological tissue constructs that mimic the anatomical and functional features of native tissues or organs. These cutting-edge technologies could...
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Advances in Three-Dimensional Bioprinting for Hard Tissue Engineering

Park SH, Jung CS, Min BH

The need for organ and tissue regeneration in patients continues to increase because of a scarcity of donors, as well as biocompatibility issues in transplant immune rejection. To address this,...
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3D Printing Technology and Its Applications for Tissue/Organ Regeneration

Ahn CB, Son KH, Lee JW

Three-dimensional (3D) printing, also known as additive manufacturing (AM), has been used frequently in regenerative or translational medicine. In addition, recent advances in 3D printing technologies have opened the door...
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Cell Sources, Liver Support Systems and Liver Tissue Engineering: Alternatives to Liver Transplantation

Lee SY, Kim HJ, Choi D

The liver is the largest organ in the body; it has a complex architecture, wide range of functions and unique regenerative capacity. The growing incidence of liver diseases worldwide requires...
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3-D Printing in Organ Transplantation

Lim G, Choi D, Richardson EB

Recently, regenerative medicine utilizing tissue manufacturing has been a creative topic of study, offering promise for resolving the gap between insufficient organ supply and transplantation needs. Moreover, 3D generation of...
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