Korean J Urol Oncol.  2018 Aug;16(2):52-57. 10.22465/kjuo.2018.16.2.52.

Application of Bioprinting to Cancer Research

• Cho MJ
• Chi BH
• Kim MJ
• Whang YM
• Chang IH

• KMID: 2438594
• DOI: http://doi.org/10.22465/kjuo.2018.16.2.52

Abstract

Three-dimensional (3D) printing is an additive manufacturing process by which precursor materials are deposited layer by layer to form complex 3D geometries from computer-aided designs, and bioprinting offers the ability to create 3D architecture living cells. Bioprinting methods have been developed rapidly pattern living cells, biological macromolecules, and biomaterials, and an advantage of the 3D microenviroment over traditional 2-dimensional cell culture is the ability to obtain more accurate and reliable data from model about tumor formation, progression, and response to anticancer therapies. This review focuses on recent advances in the use of biopriniting technologies for cancer research, bioprinting physiologically relevant testing platforms for anticancer drug development, and computational modeling for improvement bioprinting technique.

Keyword

Cancer; Microenviroment; Bioprinting

MeSH Terms

Biocompatible Materials
Bioprinting*
Cell Culture Techniques
Computer-Aided Design
Biocompatible Materials