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Endoscopic Histoacryl injection for esophagojejunostomy leakage after total gastrectomy in patients with gastric cancer

Kim MC, Shin S, Koh M

Purpose: Esophagojejunostomy leakage after total gastrectomy for gastric cancer is one of the most serious and sometimes life-threatening adverse events. The purpose of this study was to evaluate complications after...
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Approach to Patients after Successful Eradication of Helicobacter pylori

Moon HS

Helicobacter pylori (H. pylori) is a well-known gastrointestinal microorganism that causes chronic gastritis and peptic ulcers, which may evolve into gastric cancer. Previous studies have shown that H. pylori eradication...
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Identifying Disease of Interest With Deep Learning Using Diagnosis Code

Cho YS, Kim E, Stafford PL, Oh Mh, Kwon Y

Background: Autoencoder (AE) is one of the deep learning techniques that uses an artificial neural network to reconstruct its input data in the output layer. We constructed a novel supervised...
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The expression of Rab5 and its effect on invasion, migration and exosome secretion in triple negative breast cancer

Qiao L, Dong C, Zhang J, Sun G

Triple-negative breast cancer (TNBC) is the most aggressive subtype of breast cancer and current therapeutic strategies are limited in their effectiveness. The expressions of Rab5 and the M2 tumor-associated macrophage marker...
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Megakaryocyte-Derived IL-8 Acts as a Paracrine Factor for Prostate Cancer Aggressiveness through CXCR2 Activation and Antagonistic AR Downregulation

Dahal S, Chaudhary P, Jung YS, Kim JA

Prostate cancer is the fifth leading cause of cancer-related mortality in men, primarily because of treatment resistance, recurrence, and metastasis. In the present study, we investigated the role of paracrine...
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8-Methoxypsoralen Induces Apoptosis by Upregulating p53 and Inhibits Metastasis by Downregulating MMP-2 and MMP-9 in Human Gastric Cancer Cells

Choi EK, Kim HD, Park EJ, Song SY, Phan TT, Nam M, Kim M, Kim DU, Hoe KL

Furanocoumarin 8-methoxypsoralen (8-MOP) is the parent compound that naturally occurs in traditional medicinal plants used historically. 8-MOP has been employed as a photochemotherapeutic component of Psoralen + Ultraviolet A (PUVA)...
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Growth inhibition by fusidic acid in cervical, thyroid, and breast carcinoma cell lines

Kim JY, Jegal BS, Koh AR, Park KS, Kim JB, Bae J

ObjectiveWe investigated the effects of fusidic acid (FA) on human cervical, thyroid, and breast carcinoma cell lines to determine the potential usefulness of FA in cancer treatment. MethodsSix cancer cell lines...
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Investigating the Potential of Lipids for Use as Biomarkers for Glioblastoma via an Untargeted Lipidomics Approach

Soylemez B, Bulut Z, Şahin-Bölükbaşı S

Objective : The types and functions of lipids involved in glioblastoma (GB) are not well known. Lipidomics is a new field that examines cellular lipids on a large scale and...
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Comparison Trial between I-SCAN-Optical Enhancement and Chromoendoscopy for Evaluating the Horizontal Margins of Gastric Epithelial Neoplasms

Koh M, Lee JY, Han SH, Jeon SW, Kim SJ, Cho JY, Kim SH, Jang JY, Baik GH, Jang JS

Background/Aims: Endoscopic submucosal dissection is a widely used treatment for gastric epithelial neoplasms. Accurate delineation of the horizontal margins is necessary for the complete resection of gastric epithelial neoplasms. Recently,...
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Picropodophyllotoxin Inhibits Cell Growth and Induces Apoptosis in Gefitinib-Resistant Non-Small Lung Cancer Cells by Dual-Targeting EGFR and MET

Lee JY, Kang BY, Jung SJ, Kwak AW, Lee SO, Park JW, Joo SH, Yoon G, Lee MH, Shim JH

Patients with non-small-cell lung cancer (NSCLC) with epidermal growth factor receptor (EGFR) amplification or sensitive muta-tions initially respond to the tyrosine kinase inhibitor gefitinib, however, the treatment becomes less effective...
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Comparison of blood biochemical characteristics and dietary intake by sex in gastric cancer patients over 40 years in Korea based on 7 th (2016-2018) Korea National Health and Nutrition Examination Survey: a cross-sectional study

Lee HJ, Oh SW, Kim SB

Objectives: The purpose of this study was to compare the sex-associated differences in the dietary intake...
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Effects of Psychosocial Interventions for Patients with Breast Cancer: A Meta-analysis

Hwang KS, Lee KH, Yang CM, Lee HJ, Lee SY

Objective: This study involved a meta-analysis of South Korean studies regarding psychosocial interventions for patients with breast cancer to provide basic data to support the development of an integrated healthcare...
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Managing the adverse effects of cytotoxic chemotherapy at the level of primary healthcare

Hong JH

Background: Despite the increased incidence of cancer, more effective cancer drugs are being developed and cancer patient survival expectancy has been prolonged. Here, we discuss the contribution of primary healthcare...
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Outcomes of a Multi-Modal Hospital-Associated Home-Based Cancer Prehabilitation Program

Kwok KM, Tay SS

Objective To assess the impact of a “one-stop”, multi-modal, hospital-associated-home-based prehabilitation model, helmed by a small core team, on newly diagnosed gastrointestinal and urological cancer patients planned for surgery. Methods This...
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Treatment of Breast Cancer-Related Lymphedema With Topical Tacrolimus: A Prospective, Open-Label, SingleArm, Phase II Pilot Trial

Hansen FCG, Jørgensen MG, Sørensen JA

Purpose: Breast cancer-related lymphedema (BCRL) is a chronic, progressive side effect of breast cancer treatment, occurring in one-third of patients treated with axillary lymph node dissection and nodal radiotherapy. Cluster...
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Effectiveness of Adding Docetaxel to Androgen Deprivation Therapy for Metastatic Hormone-Sensitive Prostate Cancer in Korean Real-World Practice

Park K, Kim JY, Park I, Shin SH, Lee HJ, Lee JL

Purpose: Evidence in favor of adding docetaxel in treatment of metastatic hormone-sensitive prostate cancer (mHSPC) has led to docetaxel in conjunction with androgen deprivation therapy (ADT) as standard therapy. The...
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Survival after extended resections for gallbladder cancer

Bhatti ABH, Dar FS, Riyaz S, Khan NY, Qureshi NR, Khan NA

Backgrounds/Aims: Locally advanced gallbladder cancer (GBC) is associated with survival limited to a few months. Extended resections (ER) are occasionally performed in this group and outcomes remain inconclusive. This study...
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Pancreatoduodenectomy following neoadjuvant chemotherapy in duodenal adenocarcinoma

Seo D, Park BG, Jung D, Hwang HK, Kim SH, Hong SS, Kang CM

A 51-year-old male patient had four times of massive hematochezia episode three days before arrival. Carbohydrate antigen (CA) 19-9 level was extremely elevated. Computed tomography, magnetic resonance imaging, and positron...
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Neoadjuvant chemoradiotherapy versus immediate surgery for resectable and borderline resectable pancreatic cancer: Meta-analysis and trial sequential analysis of randomized controlled trials

Hajibandeh S, Hajibandeh S, Intrator C, Hassan K, Sehmbhi M, Shah J, Mazumdar E, Kausar A, Satyadas T

We aimed to compare resection and survival outcomes of neoadjuvant chemoradiotherapy (CRT) and immediate surgery in patients with resectable pancreatic cancer (RPC) or borderline resectable pancreatic cancer (BRPC). In compliance...
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Non-invasive biomarkers for liver inflammation in non-alcoholic fatty liver disease: present and future

Yip TCF, Lyu F, Lin H, Li G, Yuen PC, Wong VWS, Wong GLH

Inflammation is the key driver of liver fibrosis progression in non-alcoholic fatty liver disease (NAFLD). Unfortunately, it is often challenging to assess inflammation in NAFLD due to its dynamic nature...
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