- Vascularization Methods for Tissue Engineers
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Kim MJ, Chi BH, Cho MJ, Whang YM, Chang IH
- KMID: 2391193
- Korean J Urol Oncol.
- 2017 Aug;15(2):51-58.
- doi: 10.22465/kjuo.2017.15.2.51
Tissue engineering is limited by our inability to adequately vascularize tissues post implantation because all tissue-engineered substitutes (with the exception of cornea and cartilage) require a vascular network to provide... -
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- Evoked Potentials in Wilson Disease
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Sunwoo IN, Whang YM, Kim KW, Cho PZ
- KMID: 1661989
- J Korean Neurol Assoc.
- 1986 Dec;4(2):195-199.
Evoked potential studies including BAEP (Brainstem Auditory Evoked Potential), VEP (Visual Evoked Potential) and SEP (Somatosensory Evoked Potential-median nerve stimulated at wrist) were performed in 6 patients of wilson disease.... -
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- Manipulating the Angiogenesis by Inflammation
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Kim MJ, Jin S, Whang YM, Chang IH
- KMID: 2379753
- Korean J Urol Oncol.
- 2017 Apr;15(1):1-10.
- doi: 10.22465/kjuo.2017.15.1.1
There exists a need to develop strategies that promote neovascularization in virtually all tissue engineering and regenerative medicine efforts. While research typically focuses on understanding and exploiting the role of... -
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- Recombinant Bacille Calmette–Guérin for Immunotherapy in Nonmuscle Invasive Bladder Cancer
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Jin S, Whang YM, Chang IH
- KMID: 2368943
- Korean J Urol Oncol.
- 2016 Dec;14(3):109-117.
- doi: 10.22465/kjuo.2016.14.3.109
Intravesical instillation of Mycobacterium bovis bacille Calmette–Guérin (BCG) has been used for treating nonmuscle invasive bladder cancer as the forefront of immunotherapy, but BCG is ineffective in approximately 30–40% of... -
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- Application of Bioprinting to Cancer Research
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Cho MJ, Chi BH, Kim MJ, Whang YM, Chang IH
- KMID: 2438594
- Korean J Urol Oncol.
- 2018 Aug;16(2):52-57.
- doi: 10.22465/kjuo.2018.16.2.52
Three-dimensional (3D) printing is an additive manufacturing process by which precursor materials are deposited layer by layer to form complex 3D geometries from computer-aided designs, and bioprinting offers the ability... -
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- The Present and Future of the Cancer Microenvironment Bioprinting
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Cho MJ, Chi BH, Kim MJ, Whang YM, Chang IH
- KMID: 2402591
- Korean J Urol Oncol.
- 2017 Dec;15(3):103-110.
- doi: 10.22465/kjuo.2017.15.3.103
Cancer is the tissue complex consisted with heterogeneous cellular compositions, and microenvironmental cues. During the various stages of cancer initiation, development, and metastasis, cell–cell interactions as well as cell-extracellular matrix... -
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- Genetically Modified Bacteria as Targeted Agent for Cancer
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Jin S, Whang YM, Chang IH
- KMID: 2361564
- Korean J Urol Oncol.
- 2016 Aug;14(2):54-62.
- doi: 10.22465/kjuo.2016.14.2.54
With the emergence of microbiome as a major player in many human diseases, bacteria as therapeutics are gaining significant interest. Whole bacteria or cytotoxic or immunogenic peptides carried by them... -
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- AKAP12alpha is Associated with Promoter Methylation in Lung Cancer
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Jo U, Whang YM, Kim HK, Kim YH
- KMID: 2166059
- Cancer Res Treat.
- 2006 Jun;38(3):144-151.
PURPOSE: Promoter methylation is an important mechanism for silencing tumor-suppressor genes in cancer and it is a promising tool for the development of molecular biomarkers. The purpose of the present... -
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- Comparison of Sensitivity and Specificity of the Polymerase Chain Reaction for the M. tuberculois in CSF of Patients,Diagnosed as Tuberculous Meningitis and of Controls
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Kim KK, Kim JS, Whang YM, Lee MC, Song IS, Kim IS
- KMID: 1686771
- J Korean Neurol Assoc.
- 1993 Sep;11(3):392-403.
The diagnostic value of the DNA polymerase chain reaction for the detection of M. tuberculosis in tuberculous meningitis uas established by using cerebrospinal fluids obtained from 7 bacteriologically confirmed patients... -
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- Bacillus Calmette-Guérin (BCG)-Cell Wall Skeleton as Immunotherapeutic Option for BCG-Refractory Superficial Bladder Cancer
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Whang YM, Yoon DH, Hwang GY, Choi YW, Chang IH
- KMID: 2457592
- Korean J Urol Oncol.
- 2019 Aug;17(2):88-95.
- doi: 10.22465/kjuo.2019.17.2.88
Although intravesical instillation of Mycobacterium bovis bacillus Calmette-Guérin (BCG) is the most successful cancer immunotherapy for superficial bladder cancer, the serious side effects are frequently arisen by using live mycobacteria.... -
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- No Association between Promoter Polymorphism of STK11 Gene and Lung Cancer Risk in the Korean Population
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Sung JS, Whang YM, Park KH, Ryu JS, Choi JG, Seo JH, Shin SW, Kim JS, Kim YH
- KMID: 1972674
- Cancer Res Treat.
- 2009 Dec;41(4):211-217.
PURPOSE: Serine-threonine kinase11 (STK11) was originally identified in 1997 as the causative mutation that's responsible for Peutz-Jeghers Syndrome (PJS). Several recent studies have reported that the STK11 gene is an... -
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- RASSF1A Suppresses Cell Migration through Inactivation of HDAC6 and Increase of Acetylated alpha-Tubulin
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Jung HY, Jung JS, Whang YM, Kim YH
- KMID: 2167619
- Cancer Res Treat.
- 2013 Jun;45(2):134-144.
PURPOSE: The RAS association domain family protein 1 (RASSF1) has been implicated in a tumor-suppressive function through the induction of acetylated alpha-tubulin and modulation of cell migration. However, the mechanisms... -
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- Combinational Treatment with Retinoic Acid Derivatives in Non-small Cell Lung Carcinoma In Vitro
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Choi EJ, Whang YM, Kim SJ, Kim HJ, Kim YH
- KMID: 1785789
- J Korean Med Sci.
- 2007 Sep;22(Suppl):S52-S60.
- doi: 10.3346/jkms.2007.22.S.S52
The growth inhibitory effects of four retinoic acid (RA) derivatives, 9-cis RA, 13-cis RA, N-(4-hydroxyphenyl) retinamide (4-HPR), and all-trans retinoic acid (ATRA) were compared. In addition, the effects of various... -
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- Identification of Downstream Genes of the mTOR Pathway that Predict Recurrence and Progression in Non-Muscle Invasive High-Grade Urothelial Carcinoma of the Bladder
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Jin S, Chang IH, Kim JW, Whang YM, Kim HJ, Hong SA, Lee TJ
- KMID: 2439468
- J Korean Med Sci.
- 2017 Aug;32(8):1327-1336.
- doi: 10.3346/jkms.2017.32.8.1327
Microarray analysis was used to investigate the lack of identified mammalian target of rapamycin (mTOR) pathway downstream genes to overcome cross-talk at non-muscle invasive high-grade (HG)-urothelial carcinoma (UC) of the... -
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- NBR1 and KIF14 Downstream of the Mammarian Target of Rapamycin Pathway Predict Recurrence in Nonmuscle Invasive Low Grade Urothelial Carcinoma of the Bladder
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Lee DG, Kim HJ, Jin S, Kim JW, Whang YM, Lee TJ, Chang IH
- KMID: 2379757
- Korean J Urol Oncol.
- 2017 Apr;15(1):28-37.
- doi: 10.22465/kjuo.2017.15.1.28
PURPOSE: The lack of identified mammalian target of rapamycin (mTOR) pathway downstream genes that overcome cross-talk in nonmuscle invasive low grade (LG)-urothelial carcinoma (UC) of the bladder is a clinical... -
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- Retinoic Acid Enhances Drug-Induced Cell Death in Anticancer Drug-Resistant Cell Lines
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Whang YM, Kim YH, Shin SW, Kim BS, Kim JS, Yoo YD, Park SH
- KMID: 2134356
- Cancer Res Treat.
- 2002 Jun;34(3):212-217.
PURPOSE: Retinoids (RA), a group of vitamin A derivatives, is known to be important for regulation of normal cellular growth and differentiation. RA treatment of various cancers resulted in cell... -
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- Poloxamer 407 Hydrogels for Intravesical Instillation to Mouse Bladder: Gel-Forming Capacity and Retention Performance
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Kim SH, Kim SR, Yoon HY, Chang IH, Whang YM, Cho MJ, Kim MJ, Kim SY, Lee SJ, Choi YW
- KMID: 2402601
- Korean J Urol Oncol.
- 2017 Dec;15(3):178-186.
- doi: 10.22465/kjuo.2017.15.3.178
PURPOSE: Poloxamer 407 (P407) thermo-sensitive hydrogel formulations were developed to enhance the retention time in the urinary bladder after intravesical instillation. MATERIALS AND METHODS: P407 hydrogels (P407Gels) containing 0.2 w/w% fluorescein... -
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