Tissue Eng Regen Med.  2023 Feb;20(1):1-9. 10.1007/s13770-022-00495-9.

Research Progress of Three-Dimensional Bioprinting Artificial Cardiac Tissue

• Mao X
• Wang Z

• KMID: 2539228
• DOI: http://doi.org/10.1007/s13770-022-00495-9

Abstract

Cardiovascular disease is one of the main diseases that endanger human life and health, and heart failure often occurs when the cardiovascular disease develops to the end-stage. Heart transplantation is the most effective treatment. However, there has always been a shortage of living heart organs. With the development of regenerative medicine, researchers have turned to bioprinting technology that can build tissues and organs in vitro. A large number of relevant literature on three-dimensional (3D) bioprinted hearts were searched and screened in Google Scholar. 3D bioprinting technology can accurately print biomaterials containing living cells into 3D functional living tissues, providing a feasible solution to the shortage of transplantable organs. As one of the most important organs in the human body, the research on 3D bioprinting of the heart has currently become a hot topic. This paper briefly overviews 3D bioprinting technology and the progress in bioprinting cardiac tissue. It is believed that in the future, bio-printed hearts will become a reality, making a new way of providing artificial organs for heart transplantation.

Keyword

3D bioprinting; Cardiac; Tissue engineering; Heart transplantation