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Effects of Free Anthraquinones Extract from the Rhubarb on Cell Proliferation and Accumulation of Extracellular Matrix in High Glucose Cultured-Mesangial Cells

Wang J, Fang H, Dong B, Wang D, Li Y, Chen X, Chen L, Wei T, Wei Q

Diabetic nephropathy (DN) is the leading cause of end-stage failure of the kidney, but the efficacy of currently available strategies for the prevention of DN remains unsatisfactory. In this study,...
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Anti-Helicobacter pylori Compounds from Polygonum cuspidatum

Khalil AA, Park WS, Kim HJ, Akter KM, Ahn MJ

Anti-Helicobacter pylori activity guided fractionation led to the isolation of five anthraquinones, two stilbenes and one naphthoquinone from the EtOAc fraction of Polygonum cuspidatum, using silica gel column chromatography, Sephadex-LH20,...
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A bioactivity study of Portland cement mixed with beta-glycerophosphosphate on human pulp cell

Oh YH, Jang YJ, Cho YB

The purpose of this study is to investigate the response of human pulp cell on Portland cement mixed with beta-glycerophosphate. To investigate the effect of beta-glycerophosphate and/or dexamethasone on human...
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The biological effects of fibrin-binding synthetic oligopeptides derived from fibronectin on osteoblast-like cells

Kim YJ, Park YJ, Lee YM, Rhyu IC, Ku Y

PURPOSE: The aim of this study was to investigate the effects of synthetic fibronectin (FN) fragments, including fibrin binding sites from amino-terminal FN fragments containing type I repeats 1 to...
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Delayed Long Bone Formation in Hyperthermia-exposed Mouse Embryos

Oh SK, Choi JE, Lee J, Kim WK

  • KMID: 2283710
  • Korean J Phys Anthropol.
  • 2012 Mar;25(1):43-54.
Maternal hyperthermia, which is currently confirmed as one of major causative factors inducing growth retardation, congenital anomalies and abortion, is known to influence normal development of CNS and various organ...
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Osteogenic Differentiation of Circulating Peripheral Blood Derived Mesenchymal Progenitor Cells

Eun SC, Kim JH, Heo CY, Baek RM, Chang H, Minn KW

  • KMID: 2144712
  • J Korean Soc Plast Reconstr Surg.
  • 2008 May;35(3):229-234.
PURPOSE: There are some reports presenting that peripheral blood contain circulating hematopoietic cells as well as, in significantly smaller quantities, mesenchymal stem cells. The purposes of this study is to...
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Effects of CoCl2 on Osteogenic Differentiation of Human Mesenchymal Stem Cells

Moon YH, Son JW, Moon JS, Kang JH, Kim SH, Kim MS

  • KMID: 2170781
  • Int J Oral Biol.
  • 2013 Sep;38(3):111-119.
OBJECTIVE: To investigate the effects of the hypoxia inducible factor-1 (HIF-1) activation-mimicking agent cobalt chloride (CoCl2) on the osteogenic differentiation of human mesenchymal stem cells (hMSCs) and elucidate the underlying...
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Osteogenic Differentiation of Bone Marrow Stem Cell in Poly(Lactic-co-Glycolic Acid) Scaffold Loaded Various Ratio of Hydroxyapatite

Kim H, Kim HM, Jang JE, Kim CM, Kim EY, Lee D, Khang G

  • KMID: 1426177
  • Int J Stem Cells.
  • 2013 May;6(1):67-74.
BACKGROUND AND OBJECTIVES: Hydroxyapatite has biocompatibility and bioactivity and similar to bone of in human body. The purpose of this study is to evaluate osteogenic differentiation of bone marrow stem...
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The influence of diabetes mellitus on periodontal tissues: a pilot study

Um YJ, Jung UW, Kim CS, Bak EJ, Cha JH, Yoo YJ, Choi SH

PURPOSE: The purpose of this study was to preliminarily evaluate the influence of diabetes mellitus (DM) on periodontal tissue without establishment of periodontitis. METHODS: Seven-week-old db/db mice were used for the...
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Osteogenic differentiation of bone marrow derived stem cells in gelatin-hydroxyapatite nanocomposite

Jeon HJ, Hwang YS, Kim UK, Hwang DS, Lee KH, Chang MC

  • KMID: 2118311
  • J Korean Assoc Oral Maxillofac Surg.
  • 2009 Feb;35(1):7-12.
PURPOSE: Gelatin-hydroxyapatite nanocomposite is similar to inorganic nanostructure of bone. To make a scaffold with osteoinductivity, bone marrow derived stem cells from rabbit femur were impinged into the nanocomposite. This...
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A study on differentiation potency of adult stem cells from pulp, periodontal ligament, and dental follicle to osteoblast

Lee JK, Lee JH

Complex human tissues harbor stem cells and precursor cells, which are responsible for tissue development or repair. Recently, dental tissues such as dental pulp, periodontal ligament (PDL), dental follicle have...
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The histologic study of bone healing after horizontal ridge augmentation using auto block bone graft

Oh JK, Choi BJ, Lee BS

  • KMID: 2136956
  • J Korean Assoc Maxillofac Plast Reconstr Surg.
  • 2009 May;31(3):207-215.
PURPOSE: The aim of the present study is to evaluate the long term bone healing after horizontal ridge augmentation using auto block bone graft for implant installation timing. MATERIALS AND METHODS:...
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Osteogenesis by BMP-2 in adult stem cell derived from buccal fat pad

Kim CH, Park CH, Lee IK, Pyo SW

  • KMID: 2190166
  • J Korean Assoc Oral Maxillofac Surg.
  • 2008 Aug;34(4):412-418.
Bone morphogenetic proteins (BMPs) in combination with stem cells gain more significance for their use in bone tissue engineering. The mesenchymal stem cell can be differentiated into osteoblast by the...
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The effects of dexamethasone on the apoptosis and osteogenic differentiation of human periodontal ligament cells

Kim SM, Kim YG, Park JW, Lee JM, Suh JY

PURPOSE: The purpose of the current study was to examine the effect of dexamethasone (Dex) at various concentrations on the apoptosis and mineralization of human periodontal ligament (hPDL) cells. METHODS: hPDL...
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Effect of implant surface microtopography by hydroxyapatite grit-blasting on adhesion, proliferation, and differentiation of osteoblast-like cell line, MG-63

Park SJ, Bae SB, Kim SK, Eom TG, Song SI

OBJECTIVE: This study examined the potential of the in vitro osteogenesis of microtopographically modified surfaces, RBM (resorbable blasting media) surfaces, which generate hydroxyapatite grit-blasting. METHODS: RBM surfaces were modified hydroxyapatite...
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In vitro assay for osteoinductive activity of different demineralized freeze-dried bone allograft

Vaziri S, Vahabi S, Torshabi M, Hematzadeh S

  • KMID: 2438859
  • J Periodontal Implant Sci.
  • 2012 Dec;42(6):224-230.
PURPOSE: Various bone graft materials have been used for periodontal tissue regeneration. Demineralized freeze-dried bone allograft (DFDBA) is a widely used bone substitute. The current widespread use of DFDBA is...
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The effects of beta-TCP/rhBMP-2 on bone formation in osteoblast-like cells induced from bone marrow-derived mesenchymal stem cells

Choi YS, Hwang KG, Lee JS, Park CJ, Shim KS

  • KMID: 2190170
  • J Korean Assoc Oral Maxillofac Surg.
  • 2008 Aug;34(4):419-427.
The present study aimed to investigate the osteogenic potentials of differentiated osteoblast-like cells (DOCs) induced from bone marrow-derived mesenchymal stem cells (MSCs) on beta-tricalcium phosphate (beta-TCP) with recombinant human bone...
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Gene expression pattern during osteogenic differentiation of human periodontal ligament cells in vitro

Choi MH, Noh WC, Park JW, Lee JM, Suh JY

PURPOSE: Periodontal ligament (PDL) cell differentiation into osteoblasts is important in bone formation. Bone formation is a complex biological process and involves several tightly regulated gene expression patterns of bone-related...
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Evaluation of osteogenic activity of periosteal-derived cells treated with inflammatory cytokines

Park BW, Choi MJ, Hah YS, Cho HY, Kim DR, Kim UK, Kang HJ, Kim JR, Byun JH

  • KMID: 2328497
  • J Korean Assoc Oral Maxillofac Surg.
  • 2010 Oct;36(5):341-345.
INTRODUCTION: Skeletal homeostasis is normally maintained by the stability between bone formation by osteoblasts and bone resorption by osteoclasts. However, the correlation between the inflammatory reaction and osteoblastic differentiation of...
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Effects of immunosuppressants, FK506 and cyclosporin A, on the osteogenic differentiation of rat mesenchymal stem cells

Byun YK, Kim KH, Kim SH, Kim YS, Koo KT, Kim TI, Seol YJ, Ku Y, Rhyu IC, Lee YM

PURPOSE: The purpose of this study was to investigate the effects of the immunosuppressants FK506 and cyclosporin A (CsA) on the osteogenic differentiation of rat mesenchymal stem cells (MSCs). METHODS: The...
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