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Effects of hypothyroidism on cell proliferation and neuroblasts in the hippocampal dentate gyrus in a rat model of type 2 diabetes

Yi SS, Hwang IK, Choi JW, Won MH, Seong JK, Yoon YS

We observed how the hypothyroid state affects diabetic states and modifies cell proliferation and neuroblast differentiation in the hippocampal dentate gyrus (DG). For this, 0.03% methimazole, an anti-thyroid drug, was...
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Resected femoral anthropometry for design of the femoral component of the total knee prosthesis in a Korean population

Kwak DS, Han S, Han CW, Han SH

We measured the mediolateral (ML) and anteroposterior (AP) length, height and widths of the anterior, posterior and inferior section of the resected distal femurs using three dimensional computer tomographic measurements...
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PINK1 and Parkin to control mitochondria remodeling

Koh H, Chung J

Parkinson's disease (PD), one of the most common neurodegenerative diseases, is characterized by movement disorders and a loss of dopaminergic (DA) neurons. PD mainly occurs sporadically, but may also result...
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Tibial intramedullary canal axis and its influence on the intramedullary alignment system entry point in Koreans

Kwak DS, Han CW, Han SH

Using computerized tomographic data and three dimensional model, we studied the influence of tibial intramedullary canal axis and other morphologic factors of the tibia on the entry point for tibial...
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Migratory defect of mesencephalic dopaminergic neurons in developing reeler mice

Kang WY, Kim SS, Cho SK, Kim S, Suh-Kim H, Lee YD

Reelin, an extracellular glycoprotein has an important role in the proper migration and positioning of neurons during brain development. Lack of reelin causes not only disorganized lamination of the cerebral...
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Changes in transcript and protein levels of calbindin D28k, calretinin and parvalbumin, and numbers of neuronal populations expressing these proteins in an ischemia model of rat retina

Kim SA, Jeon JH, Son MJ, Cha J, Chun MH, Kim IB

Excessive calcium is thought to be a critical step in various neurodegenerative processes including ischemia. Calbindin D28k (CB), calretinin (CR), and parvalbumin (PV), members of the EF-hand calcium-binding protein family,...
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Combined actions of Na+/K+-ATPase, NCX1 and glutamate dependent NMDA receptors in ischemic rat brain penumbra

Park S, Jung Y

Instrumental role of Na+ and Ca2+ influx via Na+/K+ adenosine triphosphatase (Na+/K+-ATPase) and Na+/Ca2+ exchanger 1 (NCX1) is examined in the N-Methyl-D-aspartate (NMDA) receptor-mediated pathogenesis of penumbra after focal cerebral...
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Regulation of endothelial nitric oxide synthase by agmatine after transient global cerebral ischemia in rat brain

Mun CH, Lee WT, Park KA, Lee JE

Nitric oxide (NO) production by endothelial nitric oxide synthase (eNOS) plays a protective role in cerebral ischemia by maintaining vascular permeability, whereas NO derived from neuronal and inducible NOS is...
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Ethanol down regulates the expression of myelin proteolipid protein in the rat hippocampus

Lee DH, Jeong JY, Kim YS, Kim JS, Cho YW, Roh GS, Kim HJ, Kang SS, Cho GJ, Choi WS

It is well known that chronic ethanol treatment affects the synthesis of RNA and protein in the brain and the maintenance and function of nervous system. The changes in myelination-related...
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Differential regulation of Purkinje cell dendritic spines in rolling mouse Nagoya (tg(rol)/tg(rol)), P/Q type calcium channel (alpha1(A)/Ca(v)2.1) mutant

Oda SI, Lee KJ, Arii T, Imoto K, Hyun BH, Park IS, Kim H, Rhyu IJ

Voltage dependent calcium channels (VDCC) participate in regulation of neuronal Ca2+. The Rolling mouse Nagoya (Cacna1a(tg-rol) ) is a spontaneous P/Q type VDCC mutant, which has been suggested as an animal...
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