- Staurosporine and cytochalasin D induce chondrogenesis by regulation of actin dynamics in different way
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Kim M, Song K, Jin EJ, Sonn J
- KMID: 1389731
- Exp Mol Med.
- 2012 Sep;44(9):521-528.
Actin cytoskeleton has been known to control and/or be associated with chondrogenesis. Staurosporine and cytochalasin D modulate actin cytoskeleton and affect chondrogenesis. However, the underlying mechanisms for actin dynamics regulation... -
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- L-plastin: Structure, Regulation, and Roles in Cancer Invasion and in Macrophages
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Kim HJ, Lee HH
- KMID: 2452070
- J Bacteriol Virol.
- 2018 Dec;48(4):175-180.
- doi: 10.4167/jbv.2018.48.4.175
The cytoskeleton consists of 3 filamentous components: intermediate filaments, microtubules, and actin filaments. Actin filaments continuously assemble and disassemble far out of equilibrium to adapt cells in response to external... -
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- Small GTPases and formins in mammalian oocyte maturation: cytoskeletal organizers
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Kwon S, Lim HJ
- KMID: 1805481
- Clin Exp Reprod Med.
- 2011 Mar;38(1):1-5.
- doi: 10.5653/cerm.2011.38.1.1
The maturation process of mammalian oocytes accompanies an extensive rearrangement of the cytoskeleton and associated proteins. As this process requires a delicate interplay between the cytoskeleton and its regulators, it... -
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- Cytochalasin B Modulates Macrophage-Mediated Inflammatory Responses
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Kim MY, Kim JH, Cho JY
- KMID: 2170622
- Biomol Ther.
- 2014 Jul;22(4):295-300.
The actin cytoskeleton plays an important role in macrophage-mediated inflammatory responses by modulating the activation of Src and subsequently inducing nuclear factor (NF)-kappaB translocation. In spite of its critical functions,... -
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- Actin Engine in Immunological Synapse
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Piragyte I, Jun CD
- KMID: 2168004
- Immune Netw.
- 2012 Jun;12(3):71-83.
- doi: 10.4110/in.2012.12.3.71
T cell activation and function require physical contact with antigen presenting cells at a specialized junctional structure known as the immunological synapse. Once formed, the immunological synapse leads to sustained... -
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- Molecular association of CD98, CD29, and CD147 critically mediates monocytic U937 cell adhesion
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Kim MY, Cho JY
- KMID: 2350508
- Korean J Physiol Pharmacol.
- 2016 Sep;20(5):515-523.
- doi: 10.4196/kjpp.2016.20.5.515
Adhesion events of monocytes represent an important step in inflammatory responses induced by chemokines. The β1-integrin CD29 is a major adhesion molecule regulating leukocyte migration and extravasation. Although several adhesion... -
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- Current concepts of the podocyte in nephrotic syndrome
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Ding WY, Saleem MA
- KMID: 1441573
- Kidney Res Clin Pract.
- 2012 Jun;31(2):87-93.
Nephrotic syndrome is a disorder of the glomerular filtration barrier, and central to the filtration mechanism of the glomerular filtration barrier is the podocyte. We are starting to better understand... -
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- Multiple Effects of a Novel Epothilone Analog on Cellular Processes and Signaling Pathways Regulated by Rac1 GTPase in the Human Breast Cancer Cells
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Zhang H, An F, Tang L, Qiu R
- KMID: 2285499
- Korean J Physiol Pharmacol.
- 2014 Apr;18(2):109-120.
- doi: 10.4196/kjpp.2014.18.2.109
The epothilones are a class of microtubule inhibitors that exhibit a strong antitumor activity. UTD2 is a novel epothilone analog generated by genetic manipulation of the polyketide biosynthetic gene cluster.... -
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- The Effects of Cytochalasin B and Colchicine on Fine Structure of Bile Canaliculi and Hepatocytes in Mouse Liver
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Park CH, Jang BJ, Uhm CS
- KMID: 1530060
- Korean J Anat.
- 1998 Apr;31(2):241-251.
Bile canaliculi is closely related to the cytoskeleton; actin filament web, microtubules and cytokeratin intermediate filaments. To understand how cytoskeletal alteration affects bile canalicular structure, the investigators injected cytochalasin B... -
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- Diverse Effects of Small Molecule Inhibitors on Actin Cytoskeleton Dynamics in HIV-1 Infection
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Shin Y, Choi BS, Kim KC, Kim K, Yoon CH
- KMID: 2452048
- J Bacteriol Virol.
- 2019 Jun;49(2):69-80.
- doi: 10.4167/jbv.2019.49.2.69
The dynamics of the actin cytoskeleton plays a pivotal role in the process of cell division, the transportation of organelles, vesicle trafficking and cell movement. Human immunodeficiency virus type 1... -
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- In vitro treatment of lipopolysaccharide increases invasion of Pasteurella multocida serotype B:2 into bovine aortic endothelial cells
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Yap SK, Zakaria Z, Othman SS, Omar AR
- KMID: 2407620
- J Vet Sci.
- 2018 Mar;19(2):207-215.
- doi: 10.4142/jvs.2018.19.2.207
Pasteurella multocida serotype B:2 causes hemorrhagic septicemia in cattle and buffalo. The invasion mechanism of the bacterium when invading the bloodstream is unclear. This study aimed to characterize the effects... -
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- Genetic Basis of Steroid Resistant Nephrotic Syndrome
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Park E
- KMID: 2464932
- Child Kidney Dis.
- 2019 Oct;23(2):86-92.
- doi: 10.3339/jkspn.2019.23.2.86
Steroid-resistant nephrotic syndrome (SRNS) has long been a challenge for clinicians due to its poor responsiveness to immunosuppressants, and rapid progression to end-stage renal disease. Identifying a monogenic cause for... -
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- Propofol Decreases Cell Volume and Intracellular Calcium, and Rearranges Actin Filaments in Astroglial Cells
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Kim MH, Yang MK
- KMID: 2240078
- Korean J Anesthesiol.
- 1999 May;36(5):863-868.
- doi: 10.4097/kjae.1999.36.5.863
BACKGROUND: Regulation of cell volume is one of the major physiologic functions in living cells. Intracellular calcium ion and cytoskeletal component of cell membrane play pivotal roles in cell volume... -
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- A case of FLNA gene mutation with respiratory insufficiency and periventricular heterotopia
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Park H, Park MS, Ki CS, Cho J, Lee J, Kim J, Ahn K
- KMID: 2461409
- Allergy Asthma Respir Dis.
- 2019 Jul;7(3):158-164.
- doi: 10.4168/aard.2019.7.3.158
Filamin A is an actin-binding protein and, in humans, is encoded by FLNA gene in the long arm of X chromosome. Filamin A plays a role in the formation of... -
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- Genome-Wide Association Studies Associated with Backfat Thickness in Landrace and Yorkshire Pigs
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Lee YS, Shin D
- KMID: 2422813
- Genomics Inform.
- 2018 Sep;16(3):59-64.
- doi: 10.5808/GI.2018.16.3.59
Although pork quality traits are important commercially, genome-wide association studies (GWASs) have not well considered Landrace and Yorkshire pigs worldwide. Landrace and Yorkshire pigs are important pork-providing breeds. Although quantitative... -
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- Cyclic Stretch Effects on Adipose-Derived Stem Cell Stiffness, Morphology and Smooth Muscle Cell Gene Expression
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Rabbani M, Tafazzoli-Shadpour M, Shokrgozar MA, Janmaleki , Teymoori M
- KMID: 2395084
- Tissue Eng Regen Med.
- 2017 Jun;14(3):279-286.
- doi: 10.1007/s13770-017-0033-6
Recent investigations consider adipose-derived stemcells (ASCs) as a promising source of stemcells for clinical therapies. To obtain functional cells with enhanced cytoskeleton and aligned structure, mechanical stimuli are utilized during... -
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- Puromycin aminonucleoside modulates p130Cas of podocytes
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Ha TS, Choi JY, Park HY
- KMID: 2140712
- Korean J Pediatr.
- 2012 Oct;55(10):371-376.
- doi: 10.3345/kjp.2012.55.10.371
PURPOSE: Puromycin aminonucleoside (PAN) specifically injures podocytes, leading to foot process effacement, actin cytoskeleton disorganization, and abnormal distribution of slit diaphragm proteins. p130Cas is a docking protein connecting F-actin fibers... -
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- Odontogenic Ameloblast-Associated Protein (Odam) Plays Crucial Roles in Osteoclast Differentiation via Control of Actin Ring Formation
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Lee HK, Park JC
- KMID: 2154081
- J Korean Dent Sci.
- 2015 Dec;8(2):74-81.
- doi: 10.5856/JKDS.2015.8.2.74
PURPOSE: In osteoclast differentiation, actin-rich membrane protrusions play a crucial role in cell adhesion. Odontogenic ameloblast-associated protein (Odam) contributes to cell adhesion by inducing actin rearrangement. Odam-mediated RhoA activity may... -
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- The Cytoskeletal and Chromosomal Constitution in Vitrified Mouse Oocyte
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Yi BK, Kim EY, Nam HK, Lee KS, Yoon SH, Park SP, Lim JH
- KMID: 1930525
- Korean J Fertil Steril.
- 1998 Dec;25(3):287-292.
SUMMARY: The objective of this study was to confirm whether the vitrification method using EFS35 has detrimental effect for cytoskeleton and chromosome constitution of the mouse oocytes by indirect immunocytochemistry... -
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- Tyrosine phosphorylation of paxillin may be involved in vascular smooth muscle contraction
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Fang LH, Cho KS, Lee SJ, Ahn HY
- KMID: 1580807
- Korean J Physiol Pharmacol.
- 2000 Jun;4(3):211-217.
Paxillin is a regulatory component of the complex of cytoskeletal proteins that link the actin cytoskeleton to the plasma membrane. However, the role of paxillin during smooth muscle contraction is unclear. We investigated... -
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