Clin Exp Reprod Med.
2011 Mar;38(1):1-5. 10.5653/cerm.2011.38.1.1.
Small GTPases and formins in mammalian oocyte maturation: cytoskeletal organizers
- Affiliations
-
- 1Department of Biomedical Science & Technology, Institute of Biomedical Science & Technology, Research Center for Transcription Control, Konkuk University, Seoul, Korea. hlim@konkuk.ac.kr
- KMID: 1805481
- DOI: http://doi.org/10.5653/cerm.2011.38.1.1
Abstract
- The maturation process of mammalian oocytes accompanies an extensive rearrangement of the cytoskeleton and associated proteins. As this process requires a delicate interplay between the cytoskeleton and its regulators, it is often targeted by various external and internal adversaries that affect the congression and/or segregation of chromosomes. Asymmetric cell division in oocytes also requires specific regulators of the cytoskeleton, including formin-2 and small GTPases. Recent literature providing clues regarding how actin filaments and microtubules interact during spindle migration in mouse oocytes are highlighted in this review.
- Full Text Links
-
- Actions
-
Cited
- CITED
-
- Close
- Share
-
- Similar articles
-
- Studies on Timing of the Oocyte Maturation Progression in Maturation of the Mouse Oocyte in Vitro
- Epididymis and Sperm Maturation
- The Effects of Nicotine on the Mouse Oocyte Maturation In vitro
- The in Vitro Maturation of the Mouse Oocyte
- Identification of Small GTPases That Phosphorylate IRF3 through TBK1 Activation Using an Active Mutant Library Screen
