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Small GTPases and formins in mammalian oocyte maturation: cytoskeletal organizers

Kwon S, Lim HJ

The maturation process of mammalian oocytes accompanies an extensive rearrangement of the cytoskeleton and associated proteins. As this process requires a delicate interplay between the cytoskeleton and its regulators, it...
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Distribution of Peripherin Immunoreactive Axons in Rat Molar Pulp

Kim TH, Bae YC, Yang ES

Dental pulp is innervated mostly by unmyelinated axons and small myelinated axons. These axons are implicated pain transmission and contain various neurotransmitters and receptors. However, little information, so far, is...
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Properties of GST-CALM expressed in E. coli

Kim JA, Kim SR, Jung YK, Woo SY, Seoh JY, Hong YS, Kim HL

  • KMID: 1109309
  • Exp Mol Med.
  • 2000 Jun;32(2):93-99.
Clathrin-coated vesicles (CCVs) are involved in protein and lipid trafficking between intracellular compartments in eukaryotic cells. CCVs are composed of clathrin and assembly proteins. The clathrin assembly protein lymphoid...
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Expression Profiles of F4/80 and Nestin in Ocular Immune Cells Following Pharmaceutically Induced Retinal Degeneration in Adult Mice

Ahn SI, Ohn YH, Park TK

PURPOSE: To evaluate the expression patterns of F4/80 and nestin in the ciliary body and the optic nerve following N-methyl-N-nitrosourea (NMU)-induced retinal degeneration in adult mice. METHODS: After intraperitoneal injection of...
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Altered Neuronal Markers Following Treatment with Mood Stabilizer and Antipsychotic Drugs Indicate an Increased Likelihood of Neurotransmitter Release

Scarr E, Dean B

  • KMID: 2134671
  • Clin Psychopharmacol Neurosci.
  • 2012 Apr;10(1):25-33.
OBJECTIVE: Given the ability of mood stabilizers and antipsychotics to promote cell proliferation, we wanted to determine the effects of these drugs on neuronal markers previously reported to be altered...
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Expression of PSD95 in the Rat Sciatic Nerve

Yoo HJ, Cho IH, Lee JH, Choe NH, Kang TY, Chang BJ

  • KMID: 1089399
  • J Vet Sci.
  • 2003 Aug;4(2):113-116.
This study was designed to elucidate the existence of PSD95 in the rat sciatic nerve. Immunohistochemical stains of cryosection and teased fiber of sciatic nerves were performed with goat polyclonal...
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In Vivo Effects of Adipose-Derived Stem Cells in Inducing Neuronal Regeneration in Sprague-Dawley Rats Undergoing Nerve Defect Bridged with Polycaprolactone Nanotubes

Kim DY, Choi YS, Kim SE, Lee JH, Kim SM, Kim YJ, Rhie JW, Jun YJ

There have been many attempts for regeneration of peripheral nerve injury. In this study, we examined the in vivo effects of non-differentiated and neuronal differentiated adipose-derived stem cells (ADSCs) in...
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Nidogen Plays a Role in the Regenerative Axon Growth of Adult Sensory Neurons Through Schwann Cells

Lee HK, Seo IA, Suh DJ, Park HT

We previously reported that nidogen is an extracellular matrix protein regulating Schwann cell proliferation and migration. Since Schwann cells play a critical role in peripheral nerve regeneration, nidogen may play...
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The Pancreatic Tissue Regeneration and Molecular Regulators

Hong SW, Lee S, Park IS

  • KMID: 2092945
  • Korean J Anat.
  • 2008 Dec;41(4):223-230.
Pancreas is a unique organ that produces and secretes digestive enzymes to alimentary tube and supplies endocrine hormones regulating metabolic homeostasis. In the postnatal stage, pancreatic tissue is maintained by...
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Yin and Yang: the Gastric X/A-like Cell as Possible Dual Regulator of Food Intake

Stengel A, Tache Y

  • KMID: 2325878
  • J Neurogastroenterol Motil.
  • 2012 Apr;18(2):138-149.
Ingestion of food affects secretion of hormones from enteroendocrine cells located in the gastrointestinal mucosa. These hormones are involved in the regulation of various gastrointestinal functions including the control of...
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Nestin expressing progenitor cells during establishment of the neural retina and its vasculature

Lee JH, Park HS, Shin JM, Chun MH, Oh SJ

In order to test if nestin is a useful marker for various types of progenitor cells, we explored nestin expression in the retina during development. Nestin expression was co-evaluated with...
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Attenuation of Spinal Cord Injury-Induced Astroglial and Microglial Activation by Repetitive Transcranial Magnetic Stimulation in Rats

Kim JY, Choi GS, Cho YW, Cho H, Hwang SJ, Ahn SH

Spinal cord injury (SCI) causes not only loss of sensory and motor function below the level of injury but also chronic pain, which is difficult and challenging of the treatment....
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Degradation of misfolded proteins in neurodegenerative diseases: therapeutic targets and strategies

Ciechanover A, Kwon YT

Mammalian cells remove misfolded proteins using various proteolytic systems, including the ubiquitin (Ub)-proteasome system (UPS), chaperone mediated autophagy (CMA) and macroautophagy. The majority of misfolded proteins are degraded by the...
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Differentiation of Rat Neural Stem Cells Following Transplantation in the Brain of Huntington's Disease Rat Model

Ryu HL, Lee SY, Park K, Kim C, Jin BK, Min CK

Stem cells provide an important means for regenerative medicine due to the capacity to generate multiple types of differentiated cells and at the same time to maintain self-renewal. To identify...
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Cleavage of purified neuronal clathrin assembly protein (CALM) by caspase 3 and calpain

Kim JA, Kim HL

  • KMID: 1457537
  • Exp Mol Med.
  • 2001 Dec;33(4):245-250.
The most efficient means of protein internalization from the membrane are through clathrin-coated pits, which concentrate protein interactions with the clathrin-associated assembly protein complex AP-2 and internalization signals in the...
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Nerve growth factor(NGF) induces mRNA expression of the new transcription factor protein p48ZnF

Heese K, Nagai Y, Sawada T

  • KMID: 1380207
  • Exp Mol Med.
  • 2004 Apr;36(2):130-134.
Apoptosis, the cell's intrinsic death program, plays a crucial role in the regulation of tissue homeostasis, and abnormal inhibition of apoptosis is an indicator of cancer and autoimmune diseases, whereas...
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Neurochemical Properties of Dental Primary Afferent Neurons

Vang H, Chung G, Kim HY, Park SB, Jung SJ, Kim JS, Oh SB

The long belief that dental primary afferent (DPA) neurons are entirely composed of nociceptive neurons has been challenged by several anatomical and functional investigations. In order to characterize non-nociceptivepopulation among...
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Field Cancerization in Sporadic Colon Cancer

Park SK, Song CS, Yang HJ, Jung YS, Choi KY, Koo DH, Kim KE, Jeong KU, Kim HO, Kim H, Chun HK, Park DI

BACKGROUND/AIMS: Aberrant DNA methylation has a specific role in field cancerization. Certain molecular markers, including secreted frizzled-related protein 2 (SFRP2), tissue factor pathway inhibitor 2 (TFPI2), N-Myc downstream-regulated gene 4...
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Inhibition of BETA2/NeuroD by Id2

Ghil SH, Jeon YJ, Suh-Kim H

  • KMID: 755209
  • Exp Mol Med.
  • 2002 Nov;34(5):367-373.
Id (Inhibitor of Differentiation) proteins belong to a family of transcriptional modulators that are characterized by a helix loop helix (HLH) region but lack the basic amino acid domain. Id...
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Molecular cloning of clathrin assembly protein gene (rCALM) and its differential expression to AP180 in rat brain

Kim HL, Lee SC

  • KMID: 1029926
  • Exp Mol Med.
  • 1999 Dec;31(4):191-196.
Binding of clathrin assembly protein to clathrin triskelia induces their assembly into clathrin-coated vesicle (CCV) in neurons. The clathrin assembly protein gene (rCALM) was cloned from rat brain...
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