- Human platelet lysate efficiency, stability, and optimal heparin concentration required in culture of mammalian cells
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Mohamed HE, Asker ME, Kotb NS, El Habab A
- KMID: 2472006
- Blood Res.
- 2020 Mar;55(1):35-43.
- doi: 10.5045/br.2020.55.1.35
BACKGROUND: Fetal bovine serum (FBS) has been used to support the growth and proliferation of mammalian cells for decades. Owing to several risk factors associated with FBS, several trials have... -
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- Alzheimer's Disease Diagnosis Using Misfolding Proteins in Blood
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Lee H, Ugay D, Hong S, Kim Y
- KMID: 2471931
- Dement Neurocogn Disord.
- 2020 Mar;19(1):1-18.
- doi: 10.12779/dnd.2020.19.1.1
Alzheimer's disease (AD) is pathologically characterized by a long progressive phase of neuronal changes, including accumulation of extracellular amyloid-β (Aβ) and intracellular neurofibrillary tangles, before the onset of observable symptoms.... -
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- Establishment of a [¹â¸F]-FDG-PET/MRI Imaging Protocol for Gastric Cancer PDX as a Preclinical Research Tool
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Bae SW, Berlth F, Jeong KY, Suh YS, Kong SH, Lee HJ, Kim WH, Chung JK, Yang HK
- KMID: 2471926
- J Gastric Cancer.
- 2020 Mar;20(1):60-71.
- doi: 10.5230/jgc.2020.20.e7
PURPOSE: The utility of 18-fluordesoxyglucose positron emission tomography ([¹â¸F]-FDG-PET) combined with computer tomography or magnetic resonance imaging (MRI) in gastric cancer remains controversial and a rationale for patient selection is... -
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- The Amniotic Fluid Proteome Differs Significantly between Donor and Recipient Fetuses in Pregnancies Complicated by Twin-to-Twin Transfusion Syndrome
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Kim SM, Cho BK, Kim BJ, Lee HY, Norwitz ER, Kang MJ, Lee SM, Park CW, Jun JK, Yi EC, Park JS
- KMID: 2471801
- J Korean Med Sci.
- 2020 Mar;35(10):e73.
- doi: 10.3346/jkms.2020.35.e73
BACKGROUND: Twin-to-twin transfusion syndrome (TTTS) is a serious complication of monochorionic twin pregnancies. It results from disproportionate blood supply to each fetus caused by abnormal vascular anastomosis within the placenta.... -
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- Novel ABCD1 Gene Mutation in a Korean Patient with X-Linked Adrenoleukodystrophy Presenting with Addison's Disease
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Cho YK, Lee SY, Kim SW
- KMID: 2471735
- Endocrinol Metab.
- 2020 Mar;35(1):188-191.
- doi: 10.3803/EnM.2020.35.1.188
X-linked adrenoleukodystrophy (X-ALD) occurs due to mutations in the ABCD1 gene that encodes the peroxisomal membrane protein peroxisomal transporter ATP-binding cassette sub-family D member 1 (ABCD1). Degradation of very long-chain... -
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- Novel Associations between Related Proteins and Cellular Effects of High-Density Lipoprotein
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Choi S, Park YE, Cheon EJ, Kim KY, Kim M, Ann SJ, Noh HM, Lee J, Lee CJ, Lee ST, Lee C, Lee JE, Lee SH
- KMID: 2470908
- Korean Circ J.
- 2020 Mar;50(3):236-247.
- doi: 10.4070/kcj.2019.0195
BACKGROUND AND OBJECTIVES: Recent studies have examined the structure-function relationship of high-density lipoprotein (HDL). This study aimed to identify and rank HDL-associated proteins involved in several biological function of HDL. METHODS:... -
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- A Canine Model for Lymphangiography and Thoracic Duct Access
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Kim KY, Park JH, Tsauo J, Shin JH
- KMID: 2470753
- Korean J Radiol.
- 2020 Mar;21(3):298-305.
- doi: 10.3348/kjr.2019.0313
OBJECTIVE: To evaluate the technical feasibility of intranodal lymphangiography and thoracic duct (TD) access in a canine model. MATERIALS AND METHODS: Five male mongrel dogs were studied. The dog was placed... -
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- Proteomic Classification and Identification of Proteins Related to Tissue Healing of Platelet-Rich Plasma
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Lee HW, Choi KH, Kim JY, Kim KO, Haotian B, Yuxuan L, Noh KC
- KMID: 2470060
- Clin Orthop Surg.
- 2020 Mar;12(1):120-129.
- doi: 10.4055/cios.2020.12.1.120
BACKGROUND: Platelet-rich plasma (PRP) is a plasma component of autologous blood containing a high concentration of platelets. PRP is used to promote healing of damaged tissues. However, there are not... -
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- Urinary Biomarkers may Complement the Cleveland Score for Prediction of Adverse Kidney Events After Cardiac Surgery: A Pilot Study
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Albert C, Haase M, Albert A, Kropf S, Bellomo R, Westphal S, Westerman , Braun-Dullaeus RC, Haase-Fielitz A
- KMID: 2460910
- Ann Lab Med.
- 2020 Mar;40(2):131-141.
- doi: 10.3343/alm.2020.40.2.131
BACKGROUND: The ability of urinary biomarkers to complement established clinical risk prediction models for postoperative adverse kidney events is unclear. We assessed the effect of urinary biomarkers linked to suspected... -
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- Analysis of Tau Protein Expression in Predicting Pathological Complete Response to Neoadjuvant Chemotherapy in Different Molecular Subtypes of Breast Cancer
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Lei C, Yang C, Xia B, Ji F, Zhang Y, Gao H, Xiong Q, Lin Y, Zhuang X, Zhang L, Zhu T, Cheng M, Yang M, Wang K
- KMID: 2470881
- J Breast Cancer.
- 2020 Feb;23(1):47-58.
- doi: 10.4048/jbc.2020.23.e11
PURPOSE: Tau is a microtubule-associated protein that can be found in both normal and abnormal breast cells. Whether the expression of Tau protein can predict the response to neoadjuvant chemotherapy... -
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- Protocatechuic Aldehyde Represses Proliferation and Migration of Breast Cancer Cells through Targeting C-terminal Binding Protein 1
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Deng Y, Guo W, Li G, Li S, Li H, Li X, Niu B, Song M, Zhang Y, Xu Z, Li F
- KMID: 2470879
- J Breast Cancer.
- 2020 Feb;23(1):20-35.
- doi: 10.4048/jbc.2020.23.e7
PURPOSE: C-terminal binding protein 1 (CtBP1) is a transcriptional co-repressor that is overexpressed in many cancers. CtBP1 transcriptionally represses a broad array of tumor suppressors, which promotes cancer cell proliferation,... -
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- The Identification of Immune-Related Plasma Proteins Associated with Spontaneous Preterm Delivery and Intra-Amniotic Infection in Women with Premature Cervical Dilation or an Asymptomatic Short Cervix
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Park H, Hong S, Yoo HN, Kim YM, Lee SJ, Park KH
- KMID: 2470777
- J Korean Med Sci.
- 2020 Feb;35(7):e26.
- doi: 10.3346/jkms.2020.35.e26
BACKGROUND: We aimed to investigate whether various immune-related plasma proteins, alone or in combination with conventional clinical risk factors, can predict spontaneous preterm delivery (SPTD) and intra-amniotic infection in women... -
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- Current Guidelines for Non-Steroidal Anti-Inflammatory Drugs
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Park MG, Yoo JD, Lee KH
- KMID: 2470765
- J Korean Orthop Assoc.
- 2020 Feb;55(1):9-28.
- doi: 10.4055/jkoa.2020.55.1.9
Non-steroidal anti-inflammatory drugs (NSAIDs) are the most commonly used drugs worldwide for chronic pain, such as arthritis, and there are many different types depending on their composition and mechanism. After... -
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- Reverse vaccinology approach for the identification and characterization of outer membrane proteins of Shigella flexneri as potential cellular- and antibody-dependent vaccine candidates
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Leow CY, Kazi A, Hisyam Ismail CMK, Chuah C, Lim BH, Leow CH, Banga Singh KK
- KMID: 2470834
- Clin Exp Vaccine Res.
- 2020 Jan;9(1):15-25.
- doi: 10.7774/cevr.2020.9.1.15
PURPOSE: In the developing world, bacillary dysentery is one of the most common communicable diarrheal infections. There are approximately 169 million cases of shigellosis reported worldwide. The disease is transmitted... -
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- Positioning Metabolism as a Central Player in the Diabetic Heart
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Mereweather LJ, Montes Aparicio CN, Heather LC
- KMID: 2470803
- J Lipid Atheroscler.
- 2020 Jan;9(1):92-109.
- doi: 10.12997/jla.2020.9.1.92
In type 2 diabetes (T2D), the leading cause of death is cardiovascular complications. One mechanism contributing to cardiac pathogenesis is alterations in metabolism, with the diabetic heart exhibiting increased fatty... -
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- CD36 (SR-B2) as a Target to Treat Lipid Overload-Induced Cardiac Dysfunction
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Glatz JF, Luiken JJ, Nabben M
- KMID: 2470801
- J Lipid Atheroscler.
- 2020 Jan;9(1):66-78.
- doi: 10.12997/jla.2020.9.1.66
The heart faces the challenge of adjusting the rate of fatty acid uptake to match myocardial demand for energy provision at any given moment, avoiding both too low uptake rates,... -
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- Analysis of the transcripts encoding for antigenic proteins of bovine gammaherpesvirus 4
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Romeo F, Spetter MJ, Moran P, Pereyra S, Odeon A, Perez SE, Verna AE
- KMID: 2469020
- J Vet Sci.
- 2020 Jan;21(1):e5.
- doi: 10.4142/jvs.2020.21.e5
The major glycoproteins of bovine gammaherpesvirus 4 (BoHV-4) are gB, gH, gM, gL, and gp180 with gB, gH, and gp180 being the most glycosylated. These glycoproteins participate in cell binding... -
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- Ezrin-radixin-moesin proteins are regulated by Akt-GSK3β signaling in the rat nucleus accumbens core
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Kim WY, Cai WT, Jang JK, Kim JH
- KMID: 2466576
- Korean J Physiol Pharmacol.
- 2020 Jan;24(1):121-126.
- doi: 10.4196/kjpp.2020.24.1.121
The ezrin-radixin-moesin (ERM) proteins are a family of membrane-associated proteins known to play roles in cell-shape determination as well as in signaling pathways. We have previously shown that amphetamine decreases... -
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- Therapeutic Angiogenesis with Somatic Stem Cell Transplantation
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Murohara T
- KMID: 2465659
- Korean Circ J.
- 2020 Jan;50(1):12-21.
- doi: 10.4070/kcj.2019.0288
Therapeutic angiogenesis is an important strategy to rescue ischemic tissues in patients with critical limb ischemia having no other treatment option such as endovascular angioplasty or bypass surgery. Studies indicated... -
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- Microtubular Dysfunction and Male Infertility
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Gunes S, Sengupta P, Henkel R, Alguraigari A, Sinigaglia MM, Kayal M, Joumah A, Agarwal A
- KMID: 2465406
- World J Mens Health.
- 2020 Jan;38(1):9-23.
- doi: 10.5534/wjmh.180066
Microtubules are the prime component of the cytoskeleton along with microfilaments. Being vital for organelle transport and cellular divisions during spermatogenesis and sperm motility process, microtubules ascertain functional capacity of... -
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