- Microtubule-Targeting Agents Enter the Central Nervous System (CNS): Double-edged Swords for Treating CNS Injury and Disease
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Hur EM, Lee BD
- KMID: 2232730
- Int Neurourol J.
- 2014 Dec;18(4):171-178.
- doi: 10.5213/inj.2014.18.4.171
Microtubules have been among the most successful targets in anticancer therapy and a large number of microtubule-targeting agents (MTAs) are in various stages of clinical development for the treatment of... -
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- The Cytological Characteristics of the Pseudomembrane in Epidemic Keratoconjunctivitis
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Shin JC, Choe JK
- KMID: 2204877
- J Korean Ophthalmol Soc.
- 1988 Apr;29(2):239-243.
This study was performed to elucidate the cytologic characteristics of pseudomembrane, which was obtained from eight patients with epidemic keratoconjunctivltis. The predominant cells consisted of lymphocytes and degenerated epithelial cells... -
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- Understanding Schizophrenia as a Disorder of Consciousness: Biological Correlates and Translational Implications from Quantum Theory Perspectives
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Venkatasubramanian G
- KMID: 2171063
- Clin Psychopharmacol Neurosci.
- 2015 Apr;13(1):36-47.
- doi: 10.9758/cpn.2015.13.1.36
From neurophenomenological perspectives, schizophrenia has been conceptualized as "a disorder with heterogeneous manifestations that can be integrally understood to involve fundamental perturbations in consciousness". While these theoretical constructs based on... -
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- One case of Kartagener's syndrome with extracemtral microtubule in cilia
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An CH, Choi JC, Lee BH, Park YB, Jee HS, Park SJ, Kim JY, Park IW, Choi BW, Hue SH
- KMID: 1985265
- Korean J Med.
- 2000 Aug;59(2):230-234.
Kartagener's syndrome is an autosomal recessively inherited condition characterized by triad of situs inversus, bronchiectasis, and chronic sinusitis. And recently it was classified as a subclass of dyskinetic cilia syndrome,... -
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- Arsenic trioxide induces depolymerization of microtubules in an acute promyelocytic leukemia cell line
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Baek JH, Moon CH, Cha SJ, Lee HS, Noh EK, Kim H, Won JH, Min YJ
- KMID: 2083603
- Korean J Hematol.
- 2012 Jun;47(2):105-112.
- doi: 10.5045/kjh.2012.47.2.105
BACKGROUND: Arsenic trioxide (As2O3) is a well-known and effective treatment that can result in clinical remission for patients diagnosed with acute promyelocytic leukemia (APL). The biologic efficacy of As2O3 in... -
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- Microtubular Dysfunction and Male Infertility
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Gunes S, Sengupta P, Henkel R, Alguraigari A, Sinigaglia MM, Kayal M, Joumah A, Agarwal A
- KMID: 2465406
- World J Mens Health.
- 2020 Jan;38(1):9-23.
- doi: 10.5534/wjmh.180066
Microtubules are the prime component of the cytoskeleton along with microfilaments. Being vital for organelle transport and cellular divisions during spermatogenesis and sperm motility process, microtubules ascertain functional capacity of... -
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- The Effects of Cytochalasin B and Colchicine on Fine Structure of Bile Canaliculi and Hepatocytes in Mouse Liver
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Park CH, Jang BJ, Uhm CS
- KMID: 1530060
- Korean J Anat.
- 1998 Apr;31(2):241-251.
Bile canaliculi is closely related to the cytoskeleton; actin filament web, microtubules and cytokeratin intermediate filaments. To understand how cytoskeletal alteration affects bile canalicular structure, the investigators injected cytochalasin B... -
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- The Role of Microtubule in the Regulation of Endochondral Bone Formation in the Developing Mouse Cranial Base
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Kwon HJ, Lee JM, Cho KW, Shin JO, Cho SW, Lee MJ, Jung HS
- KMID: 1449629
- Korean J Phys Anthropol.
- 2011 Jun;24(2):105-112.
Endochondral bone formation of the developing cranial base is a complex process. This mechanism requires precise orchestration of many cellular events and cartilage matrix metabolism, such as proliferation, becoming round... -
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- Microtubule and Chromatic Organization in Bovine Oocytes following Intracytoplasmic Injection of Spermatozoon, Sperm Head and Tail
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Do JT, Jun SH, Choi JT, Kang YS, Lee BY, Kim SB, Kim NH, Lee HT, Chung KS
- KMID: 2235762
- Korean J Fertil Steril.
- 1997 Dec;24(3):301-309.
SUMMARY: The objective of this study was to determine the microtubule assembly and chromatin configuration during the first cell cycle in bovine oocytes following injection of spermatozoon, sperm head and... -
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- The Effect of Cytochalasin B on Cytoskeletal Stability of Mouse Oocyte Frozen by Vitrification
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Paik WY, Choi WJ, Kim SN, Lee JH
- KMID: 1566318
- Korean J Fertil Steril.
- 2002 Dec;29(4):229-236.
OBJECTIVE: The purpose of this study was to evaluate the effect of Cytochalasin B (CCB) on the cytoskeletal stability of mouse oocyte frozen by vitrification. METHODS: Mouse oocytes retrieved from cycle... -
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- A Case of Primary Ciliary Dyskinesia due to Radial Spokes Deficiency
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Kim KB, Roh JL, Lee JK, Park SW
- KMID: 1873965
- Korean J Otolaryngol-Head Neck Surg.
- 1998 Oct;41(10):1331-1334.
Primary ciliary dyskinesia encompasses a heterogenous group of inherited condition characterized by clinical, functional, and ultrastructural features. The transmission electronmicroscopic findings of nasal cilia in a 14-year old girl with... -
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- Fertilization and in vitro Development of Bovine Oocytes Following Round Spermatid Injection
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Um JH, Do JT, Kim NH, Park HD, Lee HT, Chung KS
- KMID: 2235730
- Korean J Fertil Steril.
- 1999 Aug;26(2):193-201.
SUMMARY: In this study we determined fertilization processes and developmental ability of porcine oocytes following injection of round spermatid in the presence of artificial activation. Electrical stimulation at 3 h... -
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- Stabilizing Microtubular Network Facilitates the Intracellular Growth of Orientia tsutsugamushi
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Kim MK, Kim MJ, Lim BU, Kang JS
- KMID: 2055010
- J Bacteriol Virol.
- 2006 Jun;36(2):51-57.
- doi: 10.4167/jbv.2006.36.2.51
Microtubule network provides many intracellular microbes with an efficient way to move within host cells. Orientia tsutsugamushi move from the cell periphery to the microtubule organizing center (MTOC) by dynein-dependent... -
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- Small GTPases and formins in mammalian oocyte maturation: cytoskeletal organizers
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Kwon S, Lim HJ
- KMID: 1805481
- Clin Exp Reprod Med.
- 2011 Mar;38(1):1-5.
- doi: 10.5653/cerm.2011.38.1.1
The maturation process of mammalian oocytes accompanies an extensive rearrangement of the cytoskeleton and associated proteins. As this process requires a delicate interplay between the cytoskeleton and its regulators, it... -
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- The Morphological Differences of Proprioceptors in Extraocular Muscles among Congenital, Acquired Exotropia and Congenital Nystagmus
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Yi ST, Kim SH, Cho YA
- KMID: 2337233
- J Korean Ophthalmol Soc.
- 2005 Nov;46(11):1925-1930.
PURPOSE: To evaluate morphological differences in proprioceptors in extraocular muscles between congenital exotropia, acquired exotropia and congenital nystagmus. METHODS: Nine medial recti including the myotendinous junction were resected using medial... -
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- L-plastin: Structure, Regulation, and Roles in Cancer Invasion and in Macrophages
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Kim HJ, Lee HH
- KMID: 2452070
- J Bacteriol Virol.
- 2018 Dec;48(4):175-180.
- doi: 10.4167/jbv.2018.48.4.175
The cytoskeleton consists of 3 filamentous components: intermediate filaments, microtubules, and actin filaments. Actin filaments continuously assemble and disassemble far out of equilibrium to adapt cells in response to external... -
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- Molecular Motor Proteins of the Kinesin Superfamily Proteins (KIFs): Structure, Cargo and Disease
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Seog DH, Lee DH, Lee SK
- KMID: 1785685
- J Korean Med Sci.
- 2004 Feb;19(1):1-7.
- doi: 10.3346/jkms.2004.19.1.1
Intracellular organelle transport is essential for morphogenesis and functioning of the cell. Kinesins and kinesin-related proteins make up a large superfamily of molecular motors that transport cargoes such as vesicles,... -
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- Experimental Study of Changes of beta-catenin, PCNA, Substance P after Peripheral Nerve Compression in Rat
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Yang YC, Lee SJ, Hong KH
- KMID: 2115283
- Korean J Phys Anthropol.
- 2001 Mar;14(1):97-115.
The ultrastructural changes of sciatic nerve and immunohistochemical changes of beta-catenin, PCNA, substance P were studied at the proximal segment of rat sciatic nerve after compression injury. We used 90... -
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- A Case of Paclitaxel Induced Scleroderma in a Patient with Ovarian Cancer
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Kim HJ, Seo YI, Kwon YS, Kim YM, Park EJ, Kim HA
- KMID: 2391937
- J Rheum Dis.
- 2011 Jun;18(2):110-113.
Paclitaxel takes effects as an anti-neoplastic agent by interfering with microtubules and then blocking cell growth. It has been used to treat patients with lung, ovarian, breast, head and neck... -
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- Expression of Wild Type and Truncated Myocilins in Trabecular Meshwork Cells: their Subcellular Localization
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Hur WH, Kee CW
- KMID: 2125618
- J Korean Ophthalmol Soc.
- 2003 Apr;44(4):955-964.
PURPOSE: To investigate subcellular localizations of wild type myocilin and trunctated (Q368X) myocilin in cultured human trabecular meshwork (TM) cells. METHODS: GFP and GFP tagged truncated myocilin, full-length myocilin, and... -
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