- Efficacy of the Measurement of 25-Hydroxyvitamin D2 and D3 Levels by Using PerkinElmer Liquid Chromatography-Tandem Mass Spectrometry Vitamin D Kit Compared With DiaSorin Radioimmunoassay Kit and Elecsys Vitamin D Total Assay
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Kwak HS, Chung HJ, Cho DH, Park MH, Ku ES, Park EJ, Oh HJ
- KMID: 2363192
- Ann Lab Med.
- 2015 Mar;35(2):263-265.
- doi: 10.3343/alm.2015.35.2.263
No abstract available. -
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- Ultra-Performance Liquid Chromatography-Tandem Mass Spectrometry Measurement of Leukocyte Arylsulfatase A Activity Using a Natural Substrate
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Han M, Jun SH, Song SH, Park HD, Park KU, Song J
- KMID: 2363170
- Ann Lab Med.
- 2015 Jan;35(1):165-168.
- doi: 10.3343/alm.2015.35.1.165
No abstract available. -
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- Analysis of Acid Sphingomyelinase Activity in Dried Blood Spots Using Tandem Mass Spectrometry
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Legnini E, Orsini JJ, Muhl A, Johnson B, Dajnoki A, Bodamer OA
- KMID: 1387345
- Ann Lab Med.
- 2012 Sep;32(5):319-323.
- doi: 10.3343/alm.2012.32.5.319
BACKGROUND: Niemann Pick disease (NP) is a rare, lysosomal storage disorder due to deficiency of the intra-lysosomal enzyme acid sphingomyelinase (ASM) resulting in intracellular accumulation of sphingomyelin. We evaluated a... -
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- Multiplex Assay of Second-Line Anti-Tuberculosis Drugs in Dried Blood Spots Using Ultra-Performance Liquid Chromatography-Tandem Mass Spectrometry
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Lee K, Jun SH, Han M, Song SH, Park JS, Lee JH, Park KU, Song J
- KMID: 2373581
- Ann Lab Med.
- 2016 Sep;36(5):489-493.
- doi: 10.3343/alm.2016.36.5.489
As dried blood spots (DBSs) have various advantages over conventional venous blood sampling, some assays for detection of one or two anti-tuberculosis (TB) drugs in DBSs have been developed. However,... -
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- Quantitative determination of 12-hydroxyeicosatetraenoic acids by chiral liquid chromatography tandem mass spectrometry in a murine atopic dermatitis model
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Hong SH, Han JE, Ko JS, Do SH, Lee EH, Cho MH
- KMID: 2344303
- J Vet Sci.
- 2015 Sep;16(3):307-315.
- doi: 10.4142/jvs.2015.16.3.307
Atopic dermatitis, one of the most important skin diseases, is characterized by both skin barrier impairment and immunological abnormalities. Although several studies have demonstrated the significant relationship between atopic dermatitis... -
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- Quantification of Human Plasma-Busulfan Concentration by Liquid Chromatography-Tandem Mass Spectrometry
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Moon SY, Lim MK, Hong S, Jeon Y, Han M, Song SH, Lim KS, Yu KS, Jang IJ, Lee JW, Kang HJ, Song J
- KMID: 1781353
- Ann Lab Med.
- 2014 Jan;34(1):7-14.
- doi: 10.3343/alm.2014.34.1.7
BACKGROUND: Busulfan, an alkylating agent administered prior to hematopoietic stem cell transplantation, has a narrow therapeutic range and wide variability in metabolism. We developed a liquid chromatography-tandem mass spectrometry (LC-MS/MS)... -
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- Imaging Mass Spectrometry in Papillary Thyroid Carcinoma for the Identification and Validation of Biomarker Proteins
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Min KW, Bang JY, Kim KP, Kim WS, Lee SH, Shanta SR, Lee JH, Hong JH, Lim SD, Yoo YB, Na CH
- KMID: 1789952
- J Korean Med Sci.
- 2014 Jul;29(7):934-940.
- doi: 10.3346/jkms.2014.29.7.934
Direct tissue imaging mass spectrometry (IMS) by matrix-assisted laser desorption ionization and time-of-flight (MALDI-TOF) mass spectrometry has become increasingly important in biology and medicine, because this technology can detect the... -
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- Dried Blood Spot Testing for Seven Steroids Using Liquid Chromatography-Tandem Mass Spectrometry With Reference Interval Determination in the Korean Population
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Kim B, Lee MN, Park HD, Kim JW, Chang YS, Park WS, Lee SY
- KMID: 2363260
- Ann Lab Med.
- 2015 Nov;35(6):578-585.
- doi: 10.3343/alm.2015.35.6.578
BACKGROUND: Conventional screening for congenital adrenal hyperplasia (CAH) using immunoassays generates a large number of false-positive results. A more specific liquid chromatography-tandem mass spectrometry (LC-MS/MS) method has been introduced to... -
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- A Simple and Rapid Method Based on Liquid Chromatography-Tandem Mass Spectrometry for the Measurement of alpha-L-Iduronidase Activity in Dried Blood Spots: An Application to Mucopolysaccharidosis I (Hurler) Screening
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Yang JS, Min HK, Oh HJ, Woo HI, Lee SY, Kim JW, Song J, Park HD
- KMID: 2363146
- Ann Lab Med.
- 2015 Jan;35(1):41-49.
- doi: 10.3343/alm.2015.35.1.41
BACKGROUND: We developed an analytical method to measure alpha-L-iduronidase (IDUA) activity in dried blood spots. This was achieved by using liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS) with electrospray... -
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- Liquid Chromatography-Mass Spectrometry-Based In Vitro Metabolic Profiling Reveals Altered Enzyme Expressions in Eicosanoid Metabolism
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Lee SH, Kim EJ, Lee DH, Lee WY, Chung BC, Seo HS, Choi MH
- KMID: 2373554
- Ann Lab Med.
- 2016 Jul;36(4):342-352.
- doi: 10.3343/alm.2016.36.4.342
BACKGROUND: Eicosanoids are metabolites of arachidonic acid that are rapidly biosynthesized and degraded during inflammation, and their metabolic changes reveal altered enzyme expression following drug treatment. We developed an eicosanoid... -
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- Evaluation of Serum Cotinine Cut-Off to Distinguish Smokers From Nonsmokers in the Korean Population
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Ko K, Kwon MJ, Yang SH, Moon CJ, Lee EH, Woo HY, Park H
- KMID: 2373572
- Ann Lab Med.
- 2016 Sep;36(5):427-433.
- doi: 10.3343/alm.2016.36.5.427
BACKGROUND: Cotinine has been widely used as an objective marker to identify current smokers. We conducted this study to address the absence of Korean studies investigating the efficacy of immunoassays... -
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