- Proteomics Approach in Helicobacter pylori Researches
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Chun HJ, Uhm CS, Lee SW, Hyun JH
- KMID: 2038318
- Korean J Gastroenterol.
- 2002 Apr;39(4):243-247.
Proteomics is a study of the proteome that is the whole set of proteins expressed by cell, tissue, or organism. Main techniques of proteomics are proteome separation by two-dimensional electrophoresis,... -
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- Human Genome Project
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Kwon OJ
- KMID: 2202799
- J Korean Soc Biol Psychiatry.
- 2001 Nov;8(2):196-202.
The completion of the rough draft of the human genome is a remarkable achievement. It provides the overall structures of huge DNA molecules that constitute the genome and an outline... -
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- Urine Proteomics in the Era of Mass Spectrometry
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Beasley-Green A
- KMID: 2362499
- Int Neurourol J.
- 2016 Nov;20(Suppl 2):S70-S75.
- doi: 10.5213/inj.1612720.360
With the technological advances of mass spectrometry (MS)-based platforms, clinical proteomics is one of the most rapidly growing areas in biomedical research. Urine proteomics has become a popular subdiscipline of... -
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- Vitreous Biopsy Using You's bottle: Safety and Effectiveness
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Yoo YS, Kim SG, Ahn BY, Kwon OW
- KMID: 2206313
- J Korean Ophthalmol Soc.
- 2002 Dec;43(12):2565-2569.
PURPOSE: To evaluation of the safety and the usefulness of our "You's bottle" that we have invented for sampling vitreous. METHODS: We performed the vitreous sampling with our collection bottle in... -
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- Identification of Proteome Molecules by Proteomics Using Two-Dimensional Gel Electrophoresis and MALDI-TOF MS
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Song EJ, Lee KJ
- KMID: 2038543
- Korean J Infect Dis.
- 2001 Dec;33(6):470-476.
Genomic technologies have enabled rapid accumulation of information from complex biological systems over the last two decades. The complete DNA sequence is now known for many organism and the informational... -
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- 2DSpotDB: A Database for the Annotated Two-dimensional Polyacrylamide Gel Electrophoresis of Pathogen Proteins
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Kim DW, Yoo WG, Lee MR, Kim YJ, Cho SH, Lee WJ, Ju JW
- KMID: 2053277
- Genomics Inform.
- 2011 Dec;9(4):197-199.
The biological interpretation of two-dimensional (2D) gel electrophoresis experiments is a key step toward understanding the functions of biological systems. We here present a web-based integrated database, called 2DSpotDB, for... -
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- Moyamoya Biomarkers
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Smith ER
- KMID: 2191247
- J Korean Neurosurg Soc.
- 2015 Jun;57(6):415-421.
- doi: 10.3340/jkns.2015.57.6.415
Moyamoya disease (MMD) is an arteriopathy of the intracranial circulation predominantly affecting the branches of the internal carotid arteries. Heterogeneity in presentation, progression and response to therapy has prompted intense... -
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- Bioinformatics Resources of the Korean Bioinformation Center (KOBIC)
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Lee B, Chu IS, Kim N, Lee J, Kim SY, Kim WK, Lee S
- KMID: 1806198
- Genomics Inform.
- 2010 Dec;8(4):165-169.
The Korean Bioinformation Center (KOBIC) is a national bioinformatics research center in Korea. We developed many bioinformatics algorithms and applications to facilitate the biological interpretation of OMICS data. Here we... -
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- Microarray Analysis on Allergic Inflammation
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- KMID: 2234219
- Korean J Asthma Allergy Clin Immunol.
- 2004 Dec;24(4):361-367.
It became possible to see all the expressed genes present in a cell (transcriptome) at once using microarray. We have applied microarray technology to various studies regarding allergic diseases. Although... -
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- Network-Based Protein Biomarker Discovery Platforms
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Kim M, Hwang D
- KMID: 2166534
- Genomics Inform.
- 2016 Mar;14(1):2-11.
- doi: 10.5808/GI.2016.14.1.2
The advances in mass spectrometry-based proteomics technologies have enabled the generation of global proteome data from tissue or body fluid samples collected from a broad spectrum of human diseases. Comparative... -
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- Charting the proteome of Cryptosporidium parvum sporozoites using sequence similarity-based BLAST searching
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Siddiki AM, Wastling J
- KMID: 1726919
- J Vet Sci.
- 2009 Sep;10(3):203-210.
- doi: 10.4142/jvs.2009.10.3.203
Cryptosporidium (C.) spp. are important zoonotic parasites causing widespread diarrhoeal disease in man and animals. The recent release of the complete genome sequences for C. parvum and C. hominis has... -
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- Analysis of the Cell Lysate Proteome of a Korean Mycobacterium tuberculosis Isolate K01 with H37Rv and H37Ra Strains
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Ryu SW, Park SC, Bang MN, Han SS, Park YK, Park SN, Shim YS, Kang S, Bai GH
- KMID: 2055002
- J Bacteriol Virol.
- 2004 Jun;34(2):107-112.
Despite recent economic prosperity, Korea still has high prevalence of tuberculosis. Molecular biologic characterization of Korean Mycobacterium tuberculosis strains might provide a deeper understanding of the forces contributing to the... -
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- Understanding Metabolomics in Biomedical Research
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Kim SJ, Kim SH, Kim JH, Hwang S, Yoo HJ
- KMID: 2169686
- Endocrinol Metab.
- 2016 Mar;31(1):7-16.
- doi: 10.3803/EnM.2016.31.1.7
The term "omics" refers to any type of specific study that provides collective information on a biological system. Representative omics includes genomics, proteomics, and metabolomics, and new omics is constantly... -
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- Implications of Mitochondrial Unfolded Protein Response and Mitokines: A Perspective on Fatty Liver Diseases
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Yi HS
- KMID: 2441677
- Endocrinol Metab.
- 2019 Mar;34(1):39-46.
- doi: 10.3803/EnM.2019.34.1.39
The signaling network of the mitochondrial unfolded protein response (UPR(mt)) and mitohormesis is a retrograde signaling pathway through which mitochondria-to-nucleus communication occurs in organisms. Recently, it has been shown that... -
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- Sporozoite proteome analysis of Cryptosporidium parvum by one-dimensional SDS-PAGE and liquid chromatography tandem mass spectrometry
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Siddiki AM
- KMID: 1705511
- J Vet Sci.
- 2013 Jun;14(2):107-114.
- doi: 10.4142/jvs.2013.14.2.107
Despite the development of new technologies, new challenges still remain for large scale proteomic profiling when dealing with complex biological mixtures. Fractionation prior to liquid chromatography tandem mass spectrometry (LC-MS/MS)... -
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- Possible Roles of LAMMER Kinase Lkh1 in Fission Yeast by Comparative Proteome Analysis
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Cho SJ, Kim YH, Park HM, Shin KS
- KMID: 2312575
- Mycobiology.
- 2010 Jun;38(2):108-112.
To investigate the possible roles of LAMMER kinase homologue, Lkh1, in Schizosaccharomyces pombe, whole proteins were extracted from wild type and lkh1-deletion mutant cells and subjected to polyacrylamide gel electrophoresis.... -
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- hpvPDB: An Online Proteome Reserve for Human Papillomavirus
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Kumar S, Jena L, Daf S, Mohod K, Goyal P, Varma AK
- KMID: 2166515
- Genomics Inform.
- 2013 Dec;11(4):289-291.
- doi: 10.5808/GI.2013.11.4.289
Human papillomavirus (HPV) infection is the leading cause of cancer mortality among women worldwide. The molecular understanding of HPV proteins has significant connotation for understanding their intrusion in the host... -
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- Comparison of Serum Proteome Maps of Children with Kawasaki Disease
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Baek SY, Lee YM, Lee KH, Kim DS
- KMID: 2140982
- Korean J Pediatr.
- 2004 Jan;47(1):81-89.
PURPOSE: Kawasaki disease is a systemic vasculitis observed in children under five years of age and the leading cause of pediatric acquired heart disease, but its pathophysiology is still not... -
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- Genomics and proteomics in stem cell research: the road ahead
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Ahn SM, Simpson R, Lee B
- KMID: 2168892
- Anat Cell Biol.
- 2010 Mar;43(1):1-14.
- doi: 10.5115/acb.2010.43.1.1
Stem cell research has been widely studied over the last few years and has attracted increasing attention from researchers in all fields of medicine due to its potential to treat... -
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- Identification of Leukemia Surface Proteins Using a Proteomic Technique
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Park JI, Kim HI, Lee HW, Kang SY, Jang JH, Park JS, Choi JH, Lim HY, Kim HC
- KMID: 2305214
- Korean J Hematol.
- 2006 Dec;41(4):272-281.
- doi: 10.5045/kjh.2006.41.4.272
BACKGROUND: Numerous cell surface proteins of leukemia cells such as CD33 and CD52 have been identified as diagnostic and therapeutic targets. Thus the profiling of the cell surface proteome and... -
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