Ann Child Neurol.  2019 Dec;27(4):93-104. 10.26815/acn.2019.00220.

Focal Cortical Dysplasia in Pediatric Epilepsy

Affiliations
  • 1Department of Pediatrics, Dankook University Hospital, Dankook University College of Medicine, Cheonan, Korea.
  • 2Department of Pediatrics, Pediatric Clinical Neuroscience Center, Seoul National University Children's Hospital, Seoul National University College of Medicine, Seoul, Korea. pednr@snu.ac.kr

Abstract

Focal cortical dysplasia (FCD) is the most common cause of intractable focal epilepsy in children undergoing epilepsy surgery. In these patients, seizures usually develop in early childhood and are often explosive from their onset. This review summarizes the classification of FCD and provides recent updates, clinical features, and illustrative electrophysiological and neuroimaging findings, which are expected to help physicians better understand FCD. Children with intractable focal epilepsy should receive timely evaluations for epilepsy surgery. Complete resection of the epileptogenic zone and an early surgical intervention lead to favorable surgical outcomes.

Keyword

Malformations of cortical development; Pediatrics; Epilepsy

MeSH Terms

Child
Classification
Epilepsies, Partial
Epilepsy*
Humans
Malformations of Cortical Development*
Neuroimaging
Pediatrics
Seizures
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