J Korean Neurol Assoc.  2018 Aug;36(3):139-144. 10.17340/jkna.2018.3.1.

Environmental Endocrine Disruptors and Neurological Disorders

• Yang EY
• Lee DK
• Yang JH

• KMID: 2436067
• DOI: http://doi.org/10.17340/jkna.2018.3.1

Abstract

We live in a world where daily exposure to environmental chemicals is inevitable. Many studies point to environmental chemicals a major cause of neurological diseases. Properly intervening in and managing the exposure requires up-to-date information about neurotoxic chemicals that may lead to neurological disorders. The recent literature on the neurotoxic effects of environmental chemicals was reviewed, including both animal and human studies. Parkinson's disease, Alzheimer's disease and autism are closely associated with environmental chemicals such as polychlorinated biphenys (PCBs), dioxins, polybrominated biphenyl ethers (PBDE), and perfluoroalkyls. There is strong evidence linking environmental chemical exposure to neurodevelopmental and neurodegenerative diseases. In particular, it is important to pay close attention to a high risk-age group where the window of exposure is critical to causing neurological disease.

Keyword

Alzheimer disease; Parkinson disease; Neurotoxic chemicals; Endocrine disruptors

MeSH Terms

Alzheimer Disease
Animals
Autistic Disorder
Dioxins
Endocrine Disruptors*
Ether
Ethers
Humans
Nervous System Diseases*
Neurodegenerative Diseases
Parkinson Disease
Dioxins
Endocrine Disruptors
Ether
Ethers