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Animal Models of Neurodegenerative Diseases

Cho SR

Animal models of human diseases are essentially required to investigate the pathophysiological mechanisms of the diseases, and to test potential therapies for the clinics. However, neurodegenerative diseases including Parkinson's disease...
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Neurodegenerative Disease and Speech Rehabilitation

Yoon JH

Neurodegenerative diseases such as Parkinson's disease and amyotrophic lateral sclerosis may induce impairment of speech motor system. This review discusses the characteristics of dysarthria and symptom management for these conditions....
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Photobiomodulation as a treatment for neurodegenerative disorders: current and future trends

Hong N

Photobiomodulation (PBM) is a rapidly growing as an innovative therapeutic modality for various types of diseases in recent years. Neuronal degeneration is irreversible process and it is proven to be...
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Stem Cell Therapy for Neurodegenerative Diseases

Yee JZ, Oh KW, Kim SH

Neurodegenerative diseases are the hereditary and sporadic conditions which are characterized by progressive neuronal degeneration. Neurodegenerative diseases are emerging as the leading cause of death, disabilities, and a socioeconomic burden...
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Sleep Disorders Associated With Movement Disorders and Dementia

Kim D, Oh E, Lee AY

  • KMID: 2343498
  • J Korean Neurol Assoc.
  • 2013 Nov;31(4):219-225.
Sleep disorders are common, occurring in both healthy elderly people and in association with neurodegenerative diseases, sometimes preceding other clinical manifestations of those diseases. The sleep disorders of neurodegenerative diseases...
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Sleep Disorders in Neurodegenerative Disorders

Seo JG, Park SP, Lee HW

  • KMID: 2334722
  • J Korean Sleep Res Soc.
  • 2014 Jun;11(1):1-4.
Neurodegenerative diseases result from deterioration of neurons which may eventually lead to central nervous system-related dysfunction including sleep disorders. The pathogenesis of these disturbances may be secondary to direct structural...
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Outcomes and Safety Issues Related to Percutaneous Endoscopic Gastrostomy in Neurodegenerative Diseases

Lim YJ

No abstract available.
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The Role of Oxidative Stress in Neurodegenerative Diseases

Kim GH, Kim JE, Rhie SJ, Yoon S

Oxidative stress is induced by an imbalanced redox states, involving either excessive generation of reactive oxygen species (ROS) or dysfunction of the antioxidant system. The brain is one of organs...
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Special issue on neurodegenerative diseases and their therapeutic approaches

Kim J, Mook-Jung

No abstract available.
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Molecular Genetics on the Hereditary Neurodegenerative Disorders caused by Trinucleotide Expansion

Jin DK

  • KMID: 1747711
  • J Korean Pediatr Soc.
  • 1996 Jul;39(7):894-900.
No abstract available.
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Stem Cells in Drug Screening for Neurodegenerative Disease

Kim HJ, Jin CY

Because the average human life span has recently increased, the number of patients who are diagnosed with neurodegenerative diseases has escalated. Recent advances in stem cell research have given us...
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Big data differential analysis of microglial cell responses in neurodegenerative diseases

Tabassum R, Jeong NY, Chung HJ

Microarray technology has become an indispensable tool for monitoring the levels of gene expression in a given organism through organization, analysis, interpretation, and utilization of biological sequences. Importantly, preliminary microarray...
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Potential Role of Sirtuin as a Therapeutic Target for Neurodegenerative Diseases

Han SH

The sirtuins (SIRTs) are protein-modifying enzymes that are distributed ubiquitously in all organisms. SIRT1 is a mammalian homologue of yeast nicotinamide-adenine-dinucleotide-dependent deacetylase silent information regulator 2 (known as Sir2), which...
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Rapid Eye Movement Sleep Behavior Disorder

You S, Jeon SM, Cho YW

Rapid eye movement (REM) sleep behavior disorder (RBD) is a parasomnia characterized by sleep interruption or trauma due to abnormal behaviors that occur during REM sleep. The pathophysiology of RBD...
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A Case of Idiopathic Medulla Oblongata and Upper Cervical Cord Atrophy

Park JH, Lee SS

  • KMID: 2065617
  • J Korean Neurol Assoc.
  • 2006 Oct;24(5):503-506.
Neurodegenerative diseases are featured by progressive cell loss in specific vulnerable neuronal populations of the central nervous system. Spinal cord may undergo atrophic change by degenerative disease. We present a...
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Olfaction and Neurodegenerative Disease

Kim HY

Olfactory dysfunction is an early and common symptom of many neurodegenerative diseases, particularly of Parkinson's disease, Alzheimer's disease, and mild cognitive impairment that heralds progression to dementia. Olfactory impairment is...
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Role of Oxidative Stress in Neurodegenerative Diseases and Ischemic Stroke, and Prospects of Antioxidant Therapies as a New Therapeutic Strategy

Koh SH, Kim SH

  • KMID: 2053699
  • Hanyang Med Rev.
  • 2006 Feb;26(1):33-43.
Roles of oxidative stress have recently been emphasized in the pathogenic mechanisms of neurodegenerative diseases and ischemic stroke. Many recent increasing evidence support that oxidative stress induces neuronal death related...
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Neuronal Autophagy: A Housekeeper or a Fighter in Neuronal Cell Survival?

Lee JA

Neurons have highly dynamic cellular processes for their proper functions such as cell growth, synaptic formation, or synaptic plasticity by regulating protein synthesis and degradation. Therefore, the quality control of...
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Molecular Imaging in Neurodegenerative Diseases

Kim JS, Oh SJ, Moon DH

Neurodegenerative diseases are highly morbid and widespread in the nation with aged population. Since these are progressive and irreversible diseases, early detection and differentiation of the disease are important for...
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Autophagy and Neurodegenerative Diseases

Paek J, Kim B

  • KMID: 1813203
  • J Korean Neurol Assoc.
  • 2009 Aug;27(3):206-214.
Autophagy is a highly regulated cellular mechanism that results in the bulk degradation of long-lived proteins and organelles and which seems to be implicated in a variety of physiological and...
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