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Feasibility of Robot-Assisted Gait Training with an End-Effector Type Device for Various Neurologic Disorders

Choi S, Kim SW, Jeon HR, Lee JS, Kim DY, Lee JW

Robots are being used to assist the recovery of walking ability for patients with neurologic disorders. This study aimed to evaluate the feasibility and functional improvement of training with robot-assisted...
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Status of health and nutritional intake of the elderly in long-term care facilities: focus on Gwangju Metropolitan City

Han G, Yang E

PURPOSE: This study assessed the food intake and nutritional status of the elderly in long-term care facilities in order to provide adequate food services and improve the nutritional status. METHODS: The...
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Subtypes of Sleep Disturbance in Parkinson's Disease Based on the Cross-Culturally Validated Korean Version of Parkinson's Disease Sleep Scale-2

Yang HJ, Kim HJ, Koh SB, Kim JS, Ahn TB, Cheon SM, Cho JW, Kim YJ, Ma HI, Park MY, Baik JS, Lee PH, Chung SJ, Kim JM, Song IU, Kim JY, Sung YH, Kwon DY, Lee JH, Lee JY, Kim JS, Yun JY, Kim HJ, Hong JY, Kim MJ, Youn J, Kim JS, Oh ES, Yoon WT, You S, Kwon KY, Park HE, Lee SY, Kim Y, Kim HT, Kim SJ

BACKGROUND AND PURPOSE: This study aimed to determine the clinimetric properties of the Korean version of Parkinson's Disease Sleep Scale-2 (K-PDSS-2) and whether distinct subtypes of sleep disturbance can be...
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A Cortical Substrate for Square-Wave Jerks in Progressive Supranuclear Palsy

Anagnostou E, Karavasilis E, Potiri I, Constantinides V, Efstathopoulos E, Kapaki E, Potagas C

BACKGROUND AND PURPOSE: Square-wave jerks (SWJs) are the most common saccadic intrusion in progressive supranuclear palsy (PSP), but their genesis is uncertain. We aimed to determine the characteristics of SWJs...
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Full mouth rehabilitation for a Parkinson's diseases patient with chronic periodontitis: a case report

Koh ES, Kim JJ, Baik J, Cha HS, Lee JH

Parkinson's disease is a neurological disorder characterized by tremor, bradykinesia, akinesia, postural instability, and muscular rigidity, which is caused by the depletion of neurotransmitters such as dopamine. Cooperative dental treatment...
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A Study of Korean Literature Review Related to Speech Characteristics and Speech Therapy in Patients with Parkinson Disease

Kang HN, Yoo JY

The purpose of this study was to investigate the speech characteristics and speech therapy of Parkinson disease (PD). This study selected 28 papers published in Korea from 1998 to 2018...
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A Case of Desmoplastic Melanoma in a Patient with Parkinson's Disease

Park S, Song S, Lee S, Kim H, Baek J, Park H, Roh J

No abstract available.
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Exercise and Neuroinflammation in Health and Disease

Seo DY, Heo JW, Ko JR, Kwak HB

Neuroinflammation is a central pathological feature of several acute and chronic brain diseases, including Alzheimer disease (AD), Parkinson disease (PD), amyotrophic lateral sclerosis (ALS), and multiple sclerosis (MS). It induces...
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Pharmacological Treatment in Parkinson's Disease

Lee JJ

Parkinson's disease is one of the most common neurodegenerative disorders world widely. Although curable therapies are practically not available yet, symptomatic managements using anti-Parkinson medications have shown to be quite...
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The Influence of Body Mass Index at Diagnosis on Cognitive Decline in Parkinson's Disease

Yoo HS, Chung SJ, Lee PH, Sohn YH, Kang SY

BACKGROUND AND PURPOSE: Associations between alterations in body mass index (BMI) and cognitive function have been reported in Parkinson's disease (PD). We investigated whether the BMI at a PD diagnosis...
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Combined Assessment of Serum Alpha-Synuclein and Rab35 is a Better Biomarker for Parkinson's Disease

Wang HL, Lu CS, Yeh TH, Shen YM, Weng YH, Huang YZ, Chen RS, Liu YC, Cheng YC, Chang HC, Chen YL, Chen YJ, Lin YW, Hsu CC, Lin HL, Chiu CH, Chiu CC

BACKGROUND AND PURPOSE: It is essential to develop a reliable predictive serum biomarker for Parkinson's disease (PD). The accumulation of alpha-synuclein (αSyn) and up-regulated expression of Rab35 participate in the...
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Backward Gait is Associated with Motor Symptoms and Fear of Falling in Patients with De Novo Parkinson's Disease

Kwon KY, Park S, Lee HM, Park YM, Kim J, Kim J, Koh SB

BACKGROUND AND PURPOSE: Many previous studies have investigated forward gait (FG), backward gait (BG), and dual-task gait (DG) in patients with Parkinson's disease (PD). However, it remains uncertain whether gait...
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Cholesterol Metabolism in the Brain and Its Association with Parkinson's Disease

Jin U, Park SJ, Park SM

Parkinson's disease (PD) is the second most progressive neurodegenerative disorder of the aging population after Alzheimer’s disease (AD). Defects in the lysosomal systems and mitochondria have been suspected to cause...
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Targeting Microglial and Neuronal Toll-like Receptor 2 in Synucleinopathies

Kwon S, Iba M, Masliah E, Kim C

Synucleinopathies are neurodegenerative disorders characterized by the progressive accumulation of α-synuclein (α-syn) in neurons and glia and include Parkinson's disease (PD) and dementia with Lewy bodies (DLB). In this review,...
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Intrafamilial variability and clinical heterogeneity in a family with PLA2G6-associated neurodegeneration

Park JK, Youn J, Cho JW

Phospholipase A2 group VI (PLA2G6)-associated neurodegeneration (PLAN) is an autosomal recessive neurodegenerative disease with a wide clinical spectrum; however, the genotype-phenotype correlation is unknown. Here, we report different phenotypes in...
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Benefits of Levodopa-Carbidopa Intestinal Gel Infusion in Patients with Parkinson's Disease Experiencing Gait Dysfunction Following Subthalamic Deep Brain Stimulation

Kimber TE, Zhuang Y, Thompson P

No abstract available.
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The Impact of Impulsivity on Quality of Life in Early Drug-Naïve Parkinson's Disease Patients

Ryu DW, Kim JS, Yoo SW, Oh YS, Lee KS

OBJECTIVE: Impulse control disorders (ICDs) in Parkinson's disease (PD) are mostly related to dopamine replacement therapy (DRT); however, drug-naïve PD patients have also frequently experienced impulsivity. This phenomenon makes clinicians...
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Oro-Pharyngeal Dysphagia in Parkinson's Disease and Related Movement Disorders

Kwon M, Lee JH

Oro-pharyngeal dysphagia is a common symptom in patients with Parkinson's disease (PD) and related disorders, even in their early stage of diseases. Dysphagia in these patients has been underdiagnosed, probably...
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Modeling α-Synuclein Propagation with Preformed Fibril Injections

Chung HK, Ho HA, Pérez-Acuña D, Lee SJ

The aggregation of α-synuclein (α-syn) has been implicated in the pathogenesis of many neurodegenerative disorders, including Parkinson's disease (PD), dementia with Lewy bodies (DLB), and multiple system atrophy (MSA). Postmortem...
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Urodynamic Mechanisms Underlying Overactive Bladder Symptoms in Patients With Parkinson Disease

Vurture G, Peyronnet , Palma JA, Sussman RD, Malacarne , Feigin A, Palmerola , Rosenblum , Frucht S, Kaufmann H, Nitti VW, Brucker BM

PURPOSE: To assess the urodynamic findings in patients with Parkinson disease (PD) with overactive bladder symptoms. METHODS: We performed a retrospective chart review of all PD patients who were seen in...
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