J Korean Endocr Soc.  2009 Mar;24(1):7-14. 10.3803/jkes.2009.24.1.7.

An Overview and Future Perspective on Endocrine Disruptors

• Lee CW
• Choi KH
• Jeong SW
• Kim HL
• Seo YR

• KMID: 1468489
• DOI: http://doi.org/10.3803/jkes.2009.24.1.7

Abstract

No abstract available.

MeSH Terms

Endocrine Disruptors
Endocrine Disruptors

Figure

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  Fig. 1 Mechanism of estrogen receptor-mediated transcriptional activation induced by estrogen binding to the receptor (ERE: estrogen responsive element, hsp90: heat shock protein 90, RNA Pol II: PNA polymerase II).

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  Fig. 2 Structure of the major known environmental estrogens (A) DES(diethylstilbestrol), (B) 4-Nonylphenol, (C) Bisphenol A, (D) DEHP (diethylhexylphthalate).

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  Fig. 3 Microarray process. Control mRNA and endocrine disruptors treated mRNA were hybridized into cDNA respectively. aRNA were hybridized using cDNA as a template. aRNA were labeled by Cy3 and Cy5. Each sample were mixed and hybridized on the array chip for 16 hours.

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