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Nitric Oxide Inhibitory Constituents from the Fruits of Amomum tsao-ko

Kim JG, Le TP, Hong HR, Han JS, Ko JH, Lee SH, Lee MK, Hwang BY

Bioactivity-guided fractionation of MeOH extract of the dried fruits of Amomum tsao-ko led to isolation of nine compounds (1 – 9). Their structures were elucidated by spectroscopic methods including extensive...
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Correlation of spontaneous adipocyte generation with osteogenic differentiation of porcine skin-derived stem cells

Bae HK, Jung BD, Lee S, Park CK, Yang BK, Cheong HT

The objective of this study was to examine effects of spontaneous adipocyte generation on osteogenic differentiation of porcine skin-derived stem cells (pSSCs). Correlation between osteogenic differentiation and adipocyte differentiation induced...
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Environmental Endocrine Disruptors and Neurological Disorders

Yang EY, Lee DK, Yang JH

We live in a world where daily exposure to environmental chemicals is inevitable. Many studies point to environmental chemicals a major cause of neurological diseases. Properly intervening in and managing...
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Prevalence and associated factors of intestinal parasitic infections among asymptomatic food handlers working at Haramaya University cafeterias, eastern Ethiopia

Marami D, Hailu K, Tolera M

BACKGROUND: Intestinal parasitic infections are major public health problems worldwide, with high prevalence in low income countries where substandard food hygiene practices are common. Asymptomatic food handlers with poor personal...
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Development and validation of analytical method for the determination of radotinib in human plasma using liquid chromatography-tandem mass spectrometry

Seo HB, Cho S, Yoon YR, Yim DS

This study describes the development of an analytical method to determine radotinib levels in human plasma using high performance liquid chromatography (HPLC) coupled with triple quadrupole tandem mass spectrometry (MS/MS)...
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Effects of Red or Black Ginseng Extract in a Rat Model of Inflammatory Temporomandibular Joint Pain

Lee HJ, Kim YK, Choi JH, Lee JH, Kim HJ, Seong MG, Lee MK

Temporomandibular joint (TMJ) pain is characterized by persistent jaw pain associated with dysfunction and tenderness of the temporomandibular muscles and joints. The aim of this study was to investigate whether...
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Reticulocytosis in screen-printing workers exposed to 2-butoxyethanol and 2-ethoxyethanol

Song SH, Kang SK, Choi WJ, Kwak KM, Lee DH, Kang DY, Lee SH

BACKGROUND: Studies on the hematologic toxicity of ethylene glycol ethers in humans are limited. Therefore, the aim of this study was to examine the association between exposure to solvents (containing...
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Clinical efficacy of photodynamic therapy

Park YK, Park CH

OBJECTIVE: The management of cervical intraepithelial neoplasia (CIN) and early invasive cancer of the uterine cervix is very difficult to approach, especially in case of young woman who wants to...
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Preliminary Experiences of the Combined Midline-Splitting French Door Laminoplasty with Polyether Ether Ketone (PEEK) Plate for Cervical Spondylosis and OPLL

Oh CH, Ji GY, Hur JW, Choi WS, Shin DA, Lee JB

OBJECTIVE: The purpose of this study was to evaluate the safety and efficacy of cervical midline-splitting French-door laminoplasty with a polyether ether ketone (PEEK) plate. The authors retrospectively analyzed the...
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Efficacy and Safety of Sodium Hyaluronate with 1,4-Butanediol Diglycidyl Ether Compared to Sodium Carboxymethylcellulose in Preventing Adhesion Formation after Lumbar Discectomy

Ji GY, Oh CH, Moon BG, Yi S, Han IB, Heo DH, Kim KT, Shin DA, Kim KN

OBJECTIVE: Epidural injection of hyaluronic acid may prevent adhesion formation after spine surgery, but the compounds used to stabilize hyaluronidase could interfere with its anti-adhesion effects. The present study was...
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Development of a LC-MS/MS for Quantification of Venlafaxine in Human Plasma and Application to Bioequivalence Study in healthy Korean Subjects

Kang HK, Kang MA, Kim HJ, Park YS, Kim SH, Kang JS

  • KMID: 2317857
  • Transl Clin Pharmacol.
  • 2014 Jun;22(1):35-42.
A simple, rapid and selective liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS) is developed and validated for quantification of venlafaxine in human plasma with simple liquid-liquid extraction step consisted...
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Dietary pattern classifications with nutrient intake and body composition changes in Korean elderly

Oh C, No JK, Kim HS

  • KMID: 2313729
  • Nutr Res Pract.
  • 2014 Apr;8(2):192-197.
BACKGROUND/OBJECTIVES: The body composition changes in aging increased the risk of metabolic disorder. Recent dietary studies have increasingly focused on the correlations between dietary patterns and chronic diseases to overcome...
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A Randomized, Multi-Center, Single Blind, Active-Controlled, Matched Pairs Clinical Study to Evaluate Prevention of Adhesion Formation and Safety of HyFence in Patients After Endoscopic Sinus Surgery

Chang C, Hong SM, Cho JH, Shim SY, Cho JS, Lee HM

  • KMID: 2278399
  • Clin Exp Otorhinolaryngol.
  • 2014 Mar;7(1):30-35.
OBJECTIVES: Recurrent mucosal disease and anatomic obstruction are commonly cited causes of failed endoscopic sinus surgery (ESS). Hyaluronic acid (HA) has been reported to reduce scarring and to promote wound...
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Exploration of optimum conditions for production of saccharogenic mixed grain beverages and assessment of anti-diabetic activity

Lee JS, Kang YH, Kim KK, Yun YK, Lim JG, Kim TW, Kim DJ, Won SY, Bae MH, Choi HS, Choe M

  • KMID: 2327455
  • J Nutr Health.
  • 2014 Feb;47(1):12-22.
PURPOSE: This study was conducted to establish the production conditions through optimization of the production process of beverages using Aspergillus oryzae CF1001, and to analyze volatile compounds and antidiabetic activity. METHODS:...
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Modified Formalin-Ether Concentration Technique for Diagnosis of Human Strongyloidiasis

Anamnart W, Intapan PM, Maleewong

We compared the efficacy and applicability of a modified formalin-ether concentration technique (M-FECT) to the conventional FECT (C-FECT) and the agar plate culture (APC) method for the detection of Strongyloides...
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A System for Concurrent TMS-fMRI and Evaluation of Imaging Effects

Kim JC, Kyeong S, Lee JD, Park HJ

PURPOSE: The purpose of this study was to setup a concuurent transcranial magnetic stimulation (TMS)-functional MRI (fMRI) system for understanding causality of the functional brain network. MATERIALS AND METHODS: We manufactured...
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Single Nucleotide Deletion Mutation of KCNH2 Gene is Responsible for LQT Syndrome in a 3-Generation Korean Family

Park JK, Oh YS, Choi JH, Yoon SK

Long QT syndrome (LQTS) is characterized by the prolongation of the QT interval in ECG and manifests predisposition to life threatening arrhythmia which often leads to sudden cardiac death. We...
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Genetic Mutation in Korean Patients of Sudden Cardiac Arrest as a Surrogating Marker of Idiopathic Ventricular Arrhythmia

Son MK, Ki CS, Park SJ, Huh J, Kim JS, On YK

Mutation or common intronic variants in cardiac ion channel genes have been suggested to be associated with sudden cardiac death caused by idiopathic ventricular tachyarrhythmia. This study aimed to find...
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Photodynamic Therapy for Barrett's Esophagus and Esophageal Carcinoma

Qumseya BJ, David W, Wolfsen HC

This paper reviews the use of photodynamic therapy (PDT) in patients with Barrett's esophagus and esophageal carcinoma. We describe the history of PDT, mechanics, photosensitizers for PDT in patients with...
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Advance in Photosensitizers and Light Delivery for Photodynamic Therapy

Yoon I, Li JZ, Shim YK

The brief history of photodynamic therapy (PDT) research has been focused on photosensitizers (PSs) and light delivery was introduced recently. The appropriate PSs were developed from the first generation PS...
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