J Dent Anesth Pain Med.  2016 Dec;16(4):303-307. 10.17245/jdapm.2016.16.4.303.

Efficacy evaluation of syringe pump developed for continuous drug infusion

• Jung B
• Seo KS
• Kwon SJ
• Lee K
• Hong S
• Seo H
• Kim GY
• Park GM
• Jeong J
• Seo S

• KMID: 2366159
• DOI: http://doi.org/10.17245/jdapm.2016.16.4.303

Abstract

BACKGROUND
In dental intravenous sedation, continuous intravenous infusion of a low-dose drug requires an infusion pump such as a syringe pump. To develop a new syringe pump for clinical use, the functions of the pump must meet certain international standards. Various safety and efficacy tests must be performed on the syringe pump, as stipulated by these standards, and an approval must be received from the approving agency based on such test results.
METHODS
The authors of the present study developed a novel syringe pump and performed efficacy evaluation by testing its infusion speed at 1 and 25 ml/h, and infusion performance testing at 2 and 24 h. Moreover, performance evaluation was conducted by comparing the novel pump to an existing pump with the infusion speed varied from 1 to 5 ml/h.
RESULTS
In the efficacy testing on the newly developed syringe pump, infusion with the infusion speed initially set to 1 ml/h resulted in infusion speeds of 1.00 and 0.99 ml/h in the 2- and 24-h assessment, respectively. Changing the infusion speed setting to 25 ml/h resulted in an infusion speed of 25.09 and 23.92 ml/h in the 2- and 24-h assessment, respectively. These results show no significant differences when compared with other commercially available pumps.
CONCLUSIONS
The efficacy testing of the newly developed syringe pump showed the accuracy to be within tolerance. Based on these findings, we believe that the newly developed syringe pump is suitable for clinical use.

Keyword

Data Accuracy; Flow rate; Infusion pumps

MeSH Terms

Data Accuracy
Infusion Pumps
Infusions, Intravenous
Syringes*

Figure

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  Fig. 1 The newly developed Neo syringe pump (Bionet, Co. Ltd, Seoul, Korea).

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  Fig. 2 Evaluation of accuracy based on infusion by increasing the flow rate from 1 to 5 ml/h in 10-min intervals.

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  Fig. 3 Graph of the IDA-5 measurement of the flow rate of the Neo syringe pump for 2 h after setting the flow rate to 1 ml/h.

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  Fig. 4 Graph of the IDA-5 measurement of the flow rate of the Neo syringe pump for 2 h after setting the flow rate to 25 ml/h.

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  Fig. 5 Graph of the IDA-5 measurement of the flow rate of the Neo syringe pump for 2 h after setting the flow rate to 1 ml/h.

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  Fig. 6 (A) Graph of the IDA-5 measurement of the flow rate of the Neo syringe pump for 24 h after setting the flow rate to 25 ml/h, (B) The long-term accuracy trumpet curve of pump 1 with a flow rate of 25 ml/h.

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  Fig. 7 Infusion speed comparisons among the 3 pumps with the infusion speed increased from 1 ml/h to 5 ml/h in 10-min intervals.

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